Catalog No.
RHE84603
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Alpaca
Isotype
VHH-8His-Cys-tag
Clonality
Monoclonal
Target
GPC3, MXR7, GTR2-2, Glypican-3, Intestinal protein OCI-5, OCI5
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Purified by Nickel column.
Accession
P51654
Applications
ELISA, Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
HN3
Generation of Site-Specifically Labeled Affinity Reagents via Use of a Self-Labeling Single Domain Antibody., PMID:39965119
Site-Specifically Conjugated Single-Domain Antibody Successfully Identifies Glypican-3-Expressing Liver Cancer by Immuno-PET., PMID:36997331
Human VH-based chimeric antigen receptor T cells targeting glypican 3 eliminate tumors in preclinical models of HCC., PMID:36691969
Surface Engineering of HEK293 Cell-Derived Extracellular Vesicles for Improved Pharmacokinetic Profile and Targeted Delivery of IL-12 for the Treatment of Hepatocellular Carcinoma., PMID:36660339
Nanobody-based CAR T cells targeting intracellular tumor antigens., PMID:36411612
GPC3-Unc5 receptor complex structure and role in cell migration., PMID:36240740
Production and characterization of GPC3-N protein and its nanobody., PMID:35436616
A novel PD-L1-targeted shark VNAR single-domain-based CAR-T cell strategy for treating breast cancer and liver cancer., PMID:35317524
Generation of Dual functional Nanobody-Nanoluciferase Fusion and its potential in Bioluminescence Enzyme Immunoassay for trace Glypican-3 in Serum., PMID:35250176
GPC3-targeted immunoPET imaging of hepatocellular carcinomas., PMID:35147737
Identification of nanobodies against hepatocellular carcinoma marker glypican-3., PMID:33453658
Preparation and Characterization of Anti-GPC3 Nanobody Against Hepatocellular Carcinoma., PMID:32280214
Engineered Anti-GPC3 Immunotoxin, HN3-ABD-T20, Produces Regression in Mouse Liver Cancer Xenografts Through Prolonged Serum Retention., PMID:31520528
A GPC3-targeting Bispecific Antibody, GPC3-S-Fab, with Potent Cytotoxicity., PMID:30059039
Immunotoxin targeting glypican-3 regresses liver cancer via dual inhibition of Wnt signalling and protein synthesis., PMID:25758784
Development of T cells redirected to glypican-3 for the treatment of hepatocellular carcinoma., PMID:25320357
Therapeutically targeting glypican-3 via a conformation-specific single-domain antibody in hepatocellular carcinoma., PMID:23471984
Generation and characterization of non-competitive furin-inhibiting nanobodies., PMID:22920187
For research use only. Not for human or drug use.
