Catalog No.
RHF78201
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
TNF alpha-induced protein 6, TNF-stimulated gene 6 protein, Tumor necrosis factor alpha-induced protein 6, Hyaluronate-binding protein, TSG6, Tumor necrosis factor-inducible gene 6 protein, TNFAIP6, TSG-6
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P98066
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1977
Stress-induced pro-inflammatory glioblastoma stem cells secrete TNFAIP6 to enhance tumor growth and induce suppressive macrophages., PMID:40403724
Adipose-derived mesenchymal stromal cells alleviate intestinal fibrosis: The role of tumor necrosis factor-stimulated gene 6 protein., PMID:39024752
Deciphering the Action of Neuraminidase in Glioblastoma Models., PMID:37511403
Evaluation of a gene signature related to thrombotic manifestations in antiphospholipid syndrome., PMID:37035297
An update on the role of tumor necrosis factor alpha stimulating gene-6 in inflammatory diseases., PMID:36379130
Tumor necrosis factor-alpha stimulated gene-6: A biomarker reflecting disease activity in rheumatoid arthritis., PMID:35353944
Kynurenic Acid Analog Attenuates the Production of Tumor Necrosis Factor-α, Calgranulins (S100A 8/9 and S100A 12), and the Secretion of HNP1-3 and Stimulates the Production of Tumor Necrosis Factor-Stimulated Gene-6 in Whole Blood Cultures of Patients With Rheumatoid Arthritis., PMID:33897688
Transcriptomics Study to Determine the Molecular Mechanism by which sIL-13Rα2-Fc Inhibits Caudal Intervertebral Disc Degeneration in Rats., PMID:32855969
Exosomes derived from TSG-6 modified mesenchymal stromal cells attenuate scar formation during wound healing., PMID:32800897
Encapsulated three-dimensional bioprinted structure seeded with urothelial cells: a new construction technique for tissue-engineered urinary tract patch., PMID:31977553
Human induced pluripotent stem cell-derived mesenchymal stem cells promote healing via TNF-α-stimulated gene-6 in inflammatory bowel disease models., PMID:31558705
Early gestational mesenchymal stem cell secretome attenuates experimental bronchopulmonary dysplasia in part via exosome-associated factor TSG-6., PMID:29941022
Emerging Roles of Tumor Necrosis Factor-Stimulated Gene-6 in the Pathophysiology and Treatment of Atherosclerosis., PMID:29401724
Mesenchymal Stromal Cells Inhibit Inflammatory Lymphangiogenesis in the Cornea by Suppressing Macrophage in a TSG-6-Dependent Manner., PMID:29301108
Early cellular interactions and immune transcriptome profiles in human factor VIII-exposed hemophilia A mice., PMID:29285874
Therapeutic effects of adipose-derived stem cells-based microtissues on erectile dysfunction in streptozotocin-induced diabetic rats., PMID:27345005
Tumor Necrosis Factor-stimulated Gene 6 (TSG-6)-mediated Interactions with the Inter-α-inhibitor Heavy Chain 5 Facilitate Tumor Growth Factor β1 (TGFβ1)-dependent Fibroblast to Myofibroblast Differentiation., PMID:27143355
Response to Infliximab in Crohn's Disease: Genetic Analysis Supporting Expression Profile., PMID:26339133
Tumor necrosis factor-inducible gene 6 promotes liver regeneration in mice with acute liver injury., PMID:25890163
Systematic implantation of dedifferentiated fat cells ameliorated monoclonal antibody 1-22-3-induced glomerulonephritis by immunosuppression with increases in TNF-stimulated gene 6., PMID:25889917
Cumulus cell-expressed type I interferons induce cumulus expansion in mice., PMID:25429090
Disrupted hyaluronan binding protein 1 (HABP1) expression: one of the key mediator for ovarian dysfunction in polycystic ovary rat., PMID:25300617
Modulation of tumor necrosis factor-stimulated gene-6 (TSG-6) expression in human endometrium., PMID:24213015
Cytokine and gene transcription profiles of immune responses elicited by HIV lipopeptide vaccine in HIV-negative volunteers., PMID:23759749
Irreversible heavy chain transfer to hyaluronan oligosaccharides by tumor necrosis factor-stimulated gene-6., PMID:23166324
Mesenchymal stem cells attenuate peritoneal injury through secretion of TSG-6., PMID:22912904
Hyaluronan and hyaluronan binding proteins are normal components of mouse pancreatic islets and are differentially expressed by islet endocrine cell types., PMID:22821669
Identification of developmental competence-related genes in mature porcine oocytes., PMID:21774025
Hyaluronan, TSG-6, and inter-α-inhibitor in periprosthetic breast capsules: reduced levels of free hyaluronan and TSG-6 expression in contracted capsules., PMID:21239672
TSG-6 inhibits osteoclast activity via an autocrine mechanism and is functionally synergistic with osteoprotegerin., PMID:21162099
Predictive value of epithelial gene expression profiles for response to infliximab in Crohn's disease., PMID:20848504
Hyaluronan orchestrates transforming growth factor-beta1-dependent maintenance of myofibroblast phenotype., PMID:19193641
Airway smooth muscle cells synthesize hyaluronan cable structures independent of inter-alpha-inhibitor heavy chain attachment., PMID:19075022
Synthesis of tumor necrosis factor alpha-induced protein 6 in porcine preovulatory follicles: a study with A38 antibody., PMID:18256330
Characterization of hyaluronan cable structure and function in renal proximal tubular epithelial cells., PMID:16900089
Overexpression of hyaluronan synthase 2 alters hyaluronan distribution and function in proximal tubular epithelial cells., PMID:16687630
Expression of tumor necrosis factor-alpha stimulated gene-6 mRNA in cultured human uterine cervical fibroblasts., PMID:16026405
Up-regulation of cyclooxygenase-2 expression by TSG-6 protein in macrophage cell line., PMID:15809059
TSG-6 modulates the interaction between hyaluronan and cell surface CD44., PMID:15060082
Disrupted function of tumor necrosis factor-alpha-stimulated gene 6 blocks cumulus cell-oocyte complex expansion., PMID:12959984
Role of tumour necrosis factor stimulated gene 6 (TSG-6) in the coupling of inter-alpha-trypsin inhibitor to hyaluronan in human follicular fluid., PMID:12622693
Reduced susceptibility to collagen-induced arthritis in DBA/1J mice expressing the TSG-6 transgene., PMID:12355494
Cartilage-specific constitutive expression of TSG-6 protein (product of tumor necrosis factor alpha-stimulated gene 6) provides a chondroprotective, but not antiinflammatory, effect in antigen-induced arthritis., PMID:12209527
Hyaluronan binding properties of a CD44 chimera containing the link module of TSG-6., PMID:12011075
Up-regulation and differential expression of the hyaluronan-binding protein TSG-6 in cartilage and synovium in rheumatoid arthritis and osteoarthritis., PMID:11178946
Amelioration of collagen-induced arthritis in DBA/1J mice by recombinant TSG-6, a tumor necrosis factor/interleukin-1-inducible protein., PMID:11145024
For research use only. Not for human or drug use.
