Catalog No.
RHB62801
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
WNT1-inducible-signaling pathway protein 1, WISP-1, Wnt-1-induced secreted protein, CCN4, WISP1, CCN family member 4
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O95388
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1975
The interplay of cancer-associated fibroblasts and apoptotic cancer cells suppresses lung cancer cell growth through WISP-1-integrin ανβ3-STAT1 signaling pathway., PMID:39966869
Cone-rod homeobox transcriptionally activates TCF7 to promote the proliferation of retinal pigment epithelial and retinoblastoma cells in vitro., PMID:39559312
The IL-33-ST2 axis plays a vital role in endometriosis via promoting epithelial-mesenchymal transition by phosphorylating β-catenin., PMID:38858740
Engineering c-Met-CAR NK-92 cells as a promising therapeutic candidate for lung adenocarcinoma., PMID:36640859
Evaluation of the Effects of CCN4 on Pancreatic Beta Cell Proliferation., PMID:36370351
Optimal CCN4 Immunofluorescence for Tissue Microarray., PMID:36370340
A WISP1 antibody inhibits MRTF signaling to prevent the progression of established liver fibrosis., PMID:35987202
Combined genomic and proteomic approaches reveal DNA binding sites and interaction partners of TBX2 in the developing lung., PMID:33731112
WISP1 Protects Against Chondrocyte Senescence and Apoptosis by Regulating αvβ3 and PI3K/Akt Pathway in Osteoarthritis., PMID:33646053
Mechanical Ventilation with Moderate Tidal Volume Exacerbates Extrapulmonary Sepsis-Induced Lung Injury via IL33-WISP1 Signaling Pathway., PMID:33394970
Scl-Ab reverts pro-osteoclastogenic signalling and resorption in estrogen deficient osteocytes., PMID:33148174
WNT1-inducible-signaling pathway protein 1 regulates the development of kidney fibrosis through the TGF-β1 pathway., PMID:32896021
Circ_KATNAL1 regulates prostate cancer cell growth and invasiveness through the miR-145-3p/WISP1 pathway., PMID:31800303
Multi-platform Affinity Proteomics Identify Proteins Linked to Metastasis and Immune Suppression in Ovarian Cancer Plasma., PMID:31737572
WNT1-inducible signaling protein-1 mediates TGF-β1-induced renal fibrosis in tubular epithelial cells and unilateral ureteral obstruction mouse models via autophagy., PMID:31512238
WISP1 mediates lung injury following hepatic ischemia reperfusion dependent on TLR4 in mice., PMID:30522479
Mechanical ventilation enhances extrapulmonary sepsis-induced lung injury: role of WISP1-αvβ5 integrin pathway in TLR4-mediated inflammation and injury., PMID:30445996
Mechanism of fibrogenesis in submandibular glands in patients with IgG4-RD., PMID:30251185
Osteoblast-secreted WISP-1 promotes adherence of prostate cancer cells to bone via the VCAM-1/integrin α4β1 system., PMID:29627497
WISP1 mediates IL-6-dependent proliferation in primary human lung fibroblasts., PMID:26867691
WISP1 mediates hepatic warm ischemia reperfusion injury via TLR4 signaling in mice., PMID:26821752
Blockade of CCN4 attenuates CCl4-induced liver fibrosis., PMID:26170860
A functional analysis of Wnt inducible signalling pathway protein -1 (WISP-1/CCN4)., PMID:25657057
WISP-1 contributes to fractionated irradiation-induced radioresistance in esophageal carcinoma cell lines and mice., PMID:24728101
Apoptosis signal-regulating kinase 1 is involved in WISP-1-promoted cell motility in human oral squamous cell carcinoma cells., PMID:24205072
WISP1/CCN4: a potential target for inhibiting prostate cancer growth and spread to bone., PMID:23977121
A role for WNT1-inducible signaling protein-1 in airway remodeling in a rat asthma model., PMID:23845395
CCN4 regulates vascular smooth muscle cell migration and proliferation., PMID:23807044
CCN4 induces IL-6 production through αvβ5 receptor, PI3K, Akt, and NF-κB singling pathway in human synovial fibroblasts., PMID:23343403
Role of β-catenin-regulated CCN matricellular proteins in epithelial repair after inflammatory lung injury., PMID:23316072
CCN4 induces vascular cell adhesion molecule-1 expression in human synovial fibroblasts and promotes monocyte adhesion., PMID:23313051
A quantitative systems approach to identify paracrine mechanisms that locally suppress immune response to Interleukin-12 in the B16 melanoma model., PMID:22777646
WNT1-inducible signaling pathway protein 1 contributes to ventilator-induced lung injury., PMID:22700866
Discovery of nonsteroidal anti-inflammatory drug and anticancer drug enhancing reprogramming and induced pluripotent stem cell generation., PMID:21898684
Clinical significance of Wnt-induced secreted protein-1 (WISP-1/CCN4) in esophageal squamous cell carcinoma., PMID:21498727
WISP-1 increases MMP-2 expression and cell motility in human chondrosarcoma cells., PMID:21453685
WISP-1/CCN4 regulates osteogenesis by enhancing BMP-2 activity., PMID:20684029
The potential functional interaction of biglycan and WISP-1 in controlling differentiation and proliferation of osteogenic cells., PMID:18701807
A comparative study of the expression of Wnt-1, WISP-1, survivin and cyclin-D1 in colorectal carcinoma., PMID:16041507
Overexpression of WISP-1 down-regulated motility and invasion of lung cancer cells through inhibition of Rac activation., PMID:12529380
For research use only. Not for human or drug use.
