Catalog No.
RHN06201
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
SgIgSF, Immunoglobulin superfamily member 4, SynCAM, IGSF4A, SYNCAM, TSLC1, Synaptic cell adhesion molecule, IgSF4, Tumor suppressor in lung cancer 1, TSLC-1, CADM1, Spermatogenic immunoglobulin superfamily, Nectin-like protein 2, Cell adhesion molecule 1, NECL2, IGSF4, NECL-2
Concentration
1.74 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9BY67
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1897
Multiple Functions of Cell Adhesion Molecule 1 (CADM1) and Its Role in the Pathogenesis of Cancer and Other Diseases., PMID:40399107
Alternative splicing of CADM1 is associated with endothelial progenitor cell dysfunction in preeclampsia., PMID:39928918
An antibody-drug conjugate for endometrioid carcinoma based on the expression of cell adhesion molecule 1., PMID:39252827
Relief of pain in mice by an antibody with high affinity for cell adhesion molecule 1 on nerves., PMID:39173997
Anti-tumor effect of antibody-drug conjugate targeting cell adhesion molecule 1 on GIST cells representing small intestinal GIST., PMID:39096891
Three candidate SNPs show associations with thyroid-stimulating hormone in euthyroid subjects: Tehran thyroid study., PMID:38932823
Efficient intracellular drug delivery by co-administration of two antibodies against cell adhesion molecule 1., PMID:38782061
Disruption of CADM1-dependent cell-cell adhesion in human oral squamous cell carcinoma cells results in tumor progression, possibly through an increase of MMP-2 and MMP-9 expression., PMID:38030062
Potential Contribution of Cell Adhesion Molecule 1 to the Binding of SARS-CoV-2 Spike Protein to Mouse Nasal Mucosa., PMID:37903481
Concerted Antibody and Antigen Discovery by Differential Whole-cell Phage Display Selections and Multi-omic Target Deconvolution., PMID:37019174
Innate cell markers that predict anti-HIV neutralizing antibody titers in vaccinated macaques., PMID:36167072
Possible Therapeutic Utility of anti-Cell Adhesion Molecule 1 Antibodies for Malignant Pleural Mesothelioma., PMID:35903548
A Fully-Human Antibody Specifically Targeting a Membrane-Bound Fragment of CADM1 Potentiates the T Cell-Mediated Death of Human Small-Cell Lung Cancer Cells., PMID:35805896
Gene methylation of CADM1 and MAL identified as a biomarker of high grade anal intraepithelial neoplasia., PMID:35241698
Trans-homophilic interaction of CADM1 promotes organ infiltration of T-cell lymphoma by adhesion to vascular endothelium., PMID:35213073
A CADM3 variant causes Charcot-Marie-Tooth disease with marked upper limb involvement., PMID:33889941
Differential Contribution of Cadm1-Cadm3 Cell Adhesion Molecules to Peripheral Myelinated Axons., PMID:33397712
Short Disordered Epitope of CRTAM Ig-Like V Domain as a Potential Target for Blocking Antibodies., PMID:33233764
Deficiency in the function of inhibitory interneurons contributes to glutamate-associated central sensitization through GABABR2-SynCAM1 signaling in chronic migraine rats., PMID:32931071
CADM1 enhances intestinal barrier function in a rat model of mild inflammatory bowel disease by inhibiting the STAT3 signaling pathway., PMID:32929607
Development of anti-human CADM1 monoclonal antibodies as a potential therapy for adult T-cell leukemia/lymphoma., PMID:32656636
Cell Adhesion Molecule 1 Contributes to Cell Survival in Crowded Epithelial Monolayers., PMID:32527032
Mortality and risk of progression to adult T cell leukemia/lymphoma in HTLV-1-associated myelopathy/tropical spastic paraparesis., PMID:32393644
Prokaryotic Expression of the Immunoglobulin's Domains of CRTAM to Characterize a Monoclonal Antibody., PMID:32300914
Urinary Cell Adhesion Molecule 1 Is a Novel Biomarker That Links Tubulointerstitial Damage to Glomerular Filtration Rates in Chronic Kidney Disease., PMID:31316980
Molecular Profiling of Ulcerative Colitis Subjects from the TURANDOT Trial Reveals Novel Pharmacodynamic/Efficacy Biomarkers., PMID:30901380
Renal ADAM10 and 17: Their Physiological and Medical Meanings., PMID:30460232
Expression of cell adhesion molecule 1 in gastric neck and base glandular cells: Possible involvement in peritoneal dissemination of signet ring cells., PMID:30312702
Isolation of human monoclonal antibodies that bind to two different antigens and are encoded by germline VH and VL genes., PMID:29944883
Clinicopathological analysis in PTCL-NOS with CADM1 expression., PMID:28940014
Normal intrathecal leukocyte cell number and composition do not decrease the incidence of post-lumbar puncture headache., PMID:28778448
A Unique T-Cell Receptor Amino Acid Sequence Selected by Human T-Cell Lymphotropic Virus Type 1 Tax301-309-Specific Cytotoxic T Cells in HLA-A24:02-Positive Asymptomatic Carriers and Adult T-Cell Leukemia/Lymphoma Patients., PMID:28724766
A novel oncolytic adenovirus targeting Wnt signaling effectively inhibits cancer-stem like cell growth via metastasis, apoptosis and autophagy in HCC models., PMID:28698142
Manifestation of osteoblastic phenotypes in the sarcomatous component of epithelial carcinoma and sarcomatoid carcinoma., PMID:28651491
DNA methylation signatures and coagulation factors in the peripheral blood leucocytes of epithelial ovarian cancer., PMID:28637314
Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1., PMID:28628102
Effects of Viola mandshurica on Atherosclerosis and Hepatic Steatosis in ApoE[Formula: see text] via the AMPK Pathway., PMID:28514904
CADM1 mRNA expression and clinicopathological significance in esophageal squamous cell carcinoma tissue., PMID:28510248
Cell adhesion molecule-1 (CADM1) expressed on adult T-cell leukemia/lymphoma cells is not involved in the interaction with macrophages., PMID:28420814
Negative feedback loop of bone resorption by NFATc1-dependent induction of Cadm1., PMID:28414795
miR-21 enhances cardiac fibrotic remodeling and fibroblast proliferation via CADM1/STAT3 pathway., PMID:28335740
Reaching the limits of prognostication in non-small cell lung cancer: an optimized biomarker panel fails to outperform clinical parameters., PMID:28281552
Secretome analysis to elucidate metalloprotease-dependent ectodomain shedding of glycoproteins during neuronal differentiation., PMID:28084684
Increased blood-brain barrier permeability is associated with dementia and diabetes but not amyloid pathology or APOE genotype., PMID:28061383
MPP2 is a postsynaptic MAGUK scaffold protein that links SynCAM1 cell adhesion molecules to core components of the postsynaptic density., PMID:27756895
Performance of CADM1/MAL-methylation analysis for monitoring of women treated for high-grade CIN., PMID:27430395
Excitatory Synaptic Drive and Feedforward Inhibition in the Hippocampal CA3 Circuit Are Regulated by SynCAM 1., PMID:27413156
New Developments in Mast Cell Biology: Clinical Implications., PMID:27316557
CADM1 regulates the G1/S transition and represses tumorigenicity through the Rb-E2F pathway in hepatocellular carcinoma., PMID:27298105
Effect of Cell Adhesion Molecule 1 Expression on Intracellular Granule Movement in Pancreatic α Cells., PMID:27262873
For research use only. Not for human or drug use.
