Catalog No.
RHN02001
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
C14orf27, EGFR5, C-type lectin domain family 14 member A, Epidermal growth factor receptor 5, CLEC14A, EGFR-5
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q86T13
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1855
Type-H endothelial cell protein Clec14a orchestrates osteoblast activity during trabecular bone formation and patterning., PMID:39394430
Pharmacokinetic evaluation of radiolabeled intraocular anti-CLEC14a antibody in preclinical animal species and application in humans., PMID:36129122
CAR T cells targeting tumor endothelial marker CLEC14A inhibit tumor growth., PMID:33004686
TEM8/ANTXR1-specific CAR T cells mediate toxicity in vivo., PMID:31622431
Inhibition of VEGF-dependent angiogenesis and tumor angiogenesis by an optimized antibody targeting CLEC14a., PMID:29316206
CLEC14a-HSP70-1A interaction regulates HSP70-1A-induced angiogenesis., PMID:28878328
Expression of a novel endothelial marker, C-type lectin 14A, in epithelial ovarian cancer and its prognostic significance., PMID:27567920
Blocking CLEC14A-MMRN2 binding inhibits sprouting angiogenesis and tumour growth., PMID:25745997
Human antibodies targeting the C-type lectin-like domain of the tumor endothelial cell marker clec14a regulate angiogenic properties in vitro., PMID:23644659
Identification and angiogenic role of the novel tumor endothelial marker CLEC14A., PMID:21706054
For research use only. Not for human or drug use.
