Catalog No.
RHB59301
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
EAG channel 1, KCNH1, Voltage-gated potassium channel subunit Kv10.1, h-eag, hEAG1, Ether-a-go-go potassium channel 1, EAG, EAG1, Potassium voltage-gated channel subfamily H member 1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O95259
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1808
A PAS-targeting hERG1 activator reduces arrhythmic events in Jervell and Lange-Nielsen syndrome patient-derived hiPSC-CMs., PMID:39786967
Targeting the hERG1 and β1 integrin complex for cancer treatment., PMID:38372580
Hysteretic hERG channel gating current recorded at physiological temperature., PMID:35396394
A comparison study of superovulation strategies for C57BL/6J and B6D2F1 mice in CRISPR-Cas9 mediated genome editing., PMID:34748725
Harnessing the hERG1/β1 Integrin Complex via a Novel Bispecific Single-chain Antibody: An Effective Strategy against Solid Cancers., PMID:34045227
Expression and purification of a novel single-chain diabody (scDb-hERG1/β1) from Pichia pastoris transformants., PMID:33826963
Destabilization of DNA G-Quadruplexes by Chemical Environment Changes during Tumor Progression Facilitates Transcription., PMID:29286249
Inducing Polyclonal Eag1-Specific Antibodies by Vaccination with a Linear Epitope Immunogen and Its Relation to Breast Tumorigenesis., PMID:28070819
Induction of autoimmune response to the extracellular loop of the HERG channel pore induces QTc prolongation in guinea-pigs., PMID:27296897
hERG1 behaves as biomarker of progression to adenocarcinoma in Barrett's esophagus and can be exploited for a novel endoscopic surveillance., PMID:27517748
In vivo imaging of tumour xenografts with an antibody targeting the potassium channel Kv10.1., PMID:27444284
Guiding TRAIL to cancer cells through Kv10.1 potassium channel overcomes resistance to doxorubicin., PMID:27350552
Hippocampal ether-à-go-go1 potassium channels blockade: effects in the startle reflex and prepulse inhibition., PMID:24284010
Cortactin controls surface expression of the voltage-gated potassium channel K(V)10.1., PMID:23144454
Overexpression of potassium channel ether à go-go in human osteosarcoma., PMID:22248279
Tumor cell-selective apoptosis induction through targeting of K(V)10.1 via bifunctional TRAIL antibody., PMID:21899742
Distal end of carboxyl terminus is not essential for the assembly of rat Eag1 potassium channels., PMID:21646358
Optical methods in the study of protein-protein interactions., PMID:20549938
Voltage-gated potassium channels as therapeutic targets., PMID:19949402
Estrogens and human papilloma virus oncogenes regulate human ether-à-go-go-1 potassium channel expression., PMID:19351862
Eag1: an emerging oncological target., PMID:18339837
Monoclonal antibody blockade of the human Eag1 potassium channel function exerts antitumor activity., PMID:17671204
Ether à go-go potassium channel expression in soft tissue sarcoma patients., PMID:17022811
Overexpression of Eag1 potassium channels in clinical tumours., PMID:17022810
Regulation of an ERG K+ current by Src tyrosine kinase., PMID:11834728
Interaction of the K channel beta subunit, Hyperkinetic, with eag family members., PMID:9497369
For research use only. Not for human or drug use.
