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Anti-Human AQP4/Aquaporin-4 Antibody (SAA1755)

Catalog #:   RHF09601 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: ELISA
Accession: P55087
Overview

Catalog No.

RHF09601

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

WCH4, Aquaporin-4, Mercurial-insensitive water channel, AQP-4, MIWC, AQP4

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P55087

Applications

ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA1755

Data Image
References

Emerging Role of Targeted Monoclonal Antibodies in Neuromyelitis Optica Spectrum Disorders., PMID:40506618

Relapsing anti-aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder diagnosed double positive for anti-myelin oligodendrocyte glycoprotein antibody., PMID:40506104

Oligodendroglia in Neuromyelitis Optica Spectrum Disorder., PMID:40500507

The impact of autoimmune comorbidities on the onset attack recovery in adults with AQP4-NMOSD and MOGAD., PMID:40495001

Factors for Rituximab Refractoriness in AQP4-IgG+ NMOSD: A Cohort Study., PMID:40492601

Rituximab as First-Line Compared to Escalation Immunotherapy Is Associated With Lower Disability Accumulation in Aquaporin-4-IgG-Positive Neuromyelitis Optica Spectrum Disorder: A Multicenter Cohort Study From Germany and the United Kingdom., PMID:40492480

Dual BLyS/APRIL targeted therapy with telitacicept in rituximab-refractory SLE-associated neuromyelitis optica spectrum disorder: a case report., PMID:40491913

Neuromyelitis optica in a young male patient: a case report and literature review., PMID:40486546

Comorbidities Are Associated With Unfavorable Outcome in Aquaporin-4 Antibody Positive Neuromyelitis Optica Spectrum Disorders and Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease: Exploratory Study From the CROCTINO Cohort., PMID:40485599

Tumefactive demyelination as the first presentation of MOG ab-associated disease., PMID:40479755

A Differential Proteomic Analysis on Patient Sera with Neuromyelitis Spectrum Disorders (NMOSD) and Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD) Suggested Shared and Distinct Disease Mechanisms., PMID:40464632

Translational insights from EAE models : decoding MOGAD pathogenesis and therapeutic innovation., PMID:40463369

Nausea, Vertical Gaze Palsy, and Excessive Sleep: An Unusual Presentation of Pediatric AQP4-Antibody Positive Neuromyelitis Optica Spectrum Disorder., PMID:40456289

From checkboxes to emojis: a novel approach to patient-reported outcomes in multiple sclerosis., PMID:40447786

Long-Term Effectiveness and Safety of Rituximab in Neuromyelitis Optica Spectrum Disorder: A 5-Year Observational Study., PMID:40442445

The role of IL-39 in autoimmune diseases: From general to immunopathogenesis., PMID:40440970

Early neuromyelitis optica antibody-induced molecular changes in aquaporin 4 and associated proteins at astrocyte endfeet in murine brain tissues., PMID:40436483

A Case Report of Neuromyelitis Optica Spectrum Disorder in a Young Patient With Systemic Lupus Erythematosus., PMID:40432657

AQP-4 autoantibodies as potential early diagnostic biomarkers for NEC., PMID:40424658

Anti-IL-6R antibody treatment changes microglial phenotype in AQP4 peptide-immunized mice, leading to suppression of myelitis severity., PMID:40403514

Aggressive and Refractory Attack of AQP4-IgG-Positive Neuromyelitis Optica Spectrum Disorder Treated With Ravulizumab: A Case Report., PMID:40400837

Fluctuations in serum aquaporin-4 antibody titers: the clinical significance in neuromyelitis optica spectrum disorder., PMID:40380029

Intravenous immunoglobulin for the acute treatment of refractory optic neuritis in Japan., PMID:40377800

Detrimental Roles of Innate Immune cells in Neuromyelitis Optica Spectrum Disorder: Pathogenesis and Therapeutic Targeting., PMID:40377013

Reply to Letter: Real-World Clinical Experience With Serum MOG and AQP4 Antibody Testing by Live Versus Fixed Cell-Based Assay., PMID:40368601

Letter to: Real-World Clinical Experience With Serum MOG and AQP4 Antibody Testing by Live Versus Fixed Cell-Based Assay., PMID:40368592

Anti-IL-6 receptor antibody suppresses onset of paralytic symptoms in AQP4 peptide-immunized mice without lowering bone strength or mineral density., PMID:40359583

Seronegative Autoimmune Encephalomyelitis with Area Postrema Symptoms., PMID:40336575

CD4-Positive T-Cell Responses to MOG Peptides in MOG Antibody-Associated Disease., PMID:40332104

Clinical Features and Factors Associated With Outcome in Late Adult-Onset Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease., PMID:40324120

Discontinuation of Immunotherapy in Patients With Relapsing Myelitis Without AQP4/MOG Antibodies., PMID:40317881

Worse recovery from acute attacks and faster disability accumulation highlights the unmet need for improved treatment in patients with late-onset neuromyelitis optica spectrum disorders (COPTER-LO study)., PMID:40292288

Assessing fall risk in multiple sclerosis using patient-reported outcomes and wearable gait metrics., PMID:40292035

Advances in the treatment of neuromyelitis optic spectrum disorder., PMID:40291752

Clinical characteristics and outcome of double-AQP4/MOG-seronegative and not MS-associated monophasic and relapsing demyelinating transverse myelitis: A monocenter study., PMID:40288332

The association between information processing speed and clinical features in people with multiple sclerosis and neuromyelitis optica: a comparative study., PMID:40278979

Immune-related biomarkers in the neuromyelitis optica spectrum disorder; pathogenesis and therapeutic approaches., PMID:40274184

Very late-onset neuromyelitis optica, a report of two cases., PMID:40245981

Progression independent of relapse activity and relapse-associated worsening in seronegative NMOSD: an international cohort study., PMID:40227344

Comparison of clinical features of aquaporin-4 positive neuromyelitis optica spectrum disorder (NMOSD), myelin oligodendrocyte glycoprotein associated disorder (MOGAD), and double seronegative NMOSD - A single center experience., PMID:40220551

Effectiveness of satralizumab in a real-world clinical setting in Japan: Interleukin-6 receptor inhibition in neuromyelitis optica spectrum disorder: A six-month interim analysis of a multicenter medical chart review., PMID:40203604

Epidemiology of aquaporin-4 seropositive neuromyelitis optica spectrum disorder in the Alicante health area, Spain: A population-based study., PMID:40203603

Intractable Vomiting and Hiccups: An Atypical Presentation of Neuromyelitis Optica Spectrum Disorder., PMID:40200627

Telitacicept: A New Therapy for the Treatment of Optic Neuromyelitis Spectrum Disease Associated with Other Autoimmune Disorders., PMID:40196354

Satralizumab after inebilizumab treatment in a patient with recurrent neuromyelitis optica spectrum disorder: A case report., PMID:40193676

Ethnic and racial differences in MOG antibodies findings in seronegative NMOSD patients: Insights from Buenos Aires, Argentina., PMID:40188628

Concomitant Sjögren's disease in patients with NMOSD: impacts on neurologic disease severity and recurrence., PMID:40188346

Comparison of the clinical and laboratory characteristics of neuromyelitis optica spectrum disorder with or without cerebrospinal fluid oligoclonal bands: a cohort with 36-month follow-up., PMID:40160821

Comparison of vision-related quality of life in NMOSD and MOGAD., PMID:40157039

The immunological processes behind aquaporin 4-antibody seropositive neuromyelitis optica spectrum disorders., PMID:40154151

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1640

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Anti-Human AQP4/Aquaporin-4 Antibody (SAA1755) [RHF09601]
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