Catalog No.
RHJ80701
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
APEL, Apelin, APJ endogenous ligand, APLN
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9ULZ1
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1754
Perspective on Renal Involvement in Antiphospholipid Syndrome: Implications for Diagnosis, Pathogenesis, and Treatment., PMID:40429322
Anti-phospholipid antibodies nephropathy is associated with an increased risk of kidney failure: a systematic literature review and meta-analysis., PMID:39449994
Efforts to Better Characterize "Antiphospholipid Antibody Nephropathy" for the 2023 ACR/EULAR Antiphospholipid Syndrome Classification Criteria: Renal Pathology Subcommittee Report., PMID:37399462
Immunosuppression use in primary antiphospholipid antibody-positive patients: Descriptive analysis of the AntiPhospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking (APS ACTION) Clinical Database and Repository ("Registry")., PMID:36206383
Apelin Promotes Endothelial Progenitor Cell Angiogenesis in Rheumatoid Arthritis Disease via the miR-525-5p/Angiopoietin-1 Pathway., PMID:34659230
Apelin/APJ signaling activates autophagy to promote human lung adenocarcinoma cell migration., PMID:34186050
The Role of Apelin and Apelin Receptor Expression in Migration and Invasiveness of Colon Cancer Cells., PMID:33419808
A woman with systemic lupus erythematosus, multiple pregnancy complications, and cerebral infarction who was only positive for phosphatidylserine-dependent antiprothrombin antibodies., PMID:33269657
Apelin/APJ signaling suppresses the pressure ulcer formation in cutaneous ischemia-reperfusion injury mouse model., PMID:31992828
Anti-beta-2-glycoprotein I domain 1 identifies antiphospholipid antibodies-related injuries in patients with concomitant lupus nephritis., PMID:31974856
Targeting APLN/APLNR Improves Antiangiogenic Efficiency and Blunts Proinvasive Side Effects of VEGFA/VEGFR2 Blockade in Glioblastoma., PMID:30718358
Early Renin-angiotensin System Blockade Improved Short-term and Longterm Renal Outcomes in Systemic Lupus Erythematosus Patients with Antiphospholipid-associated Nephropathy., PMID:29449503
Apelin: A putative novel predictive biomarker for bevacizumab response in colorectal cancer., PMID:28487489
Apelin-36 Modulates Blood Glucose and Body Weight Independently of Canonical APJ Receptor Signaling., PMID:27994053
Beta2-glycoprotein I Expression in Lupus Nephritis Patients with Antiphospholipid-associated Nephropathy., PMID:27633824
Apelin as a marker for monitoring the tumor vessel normalization window during antiangiogenic therapy., PMID:26475217
Histological antiphospholipid-associated nephropathy versus lupus nephritis in patients with systemic lupus erythematosus: an observational cross-sectional study with longitudinal follow-up., PMID:25927214
Apelin in epiretinal membranes of patients with proliferative diabetic retinopathy., PMID:25324682
Mechanisms involved in dual vasopressin/apelin neuron dysfunction during aging., PMID:24505289
Laser-induced choroidal neovascularization in mice attenuated by deficiency in the apelin-APJ system., PMID:23722395
Apelin serum levels in non-diabetic ankylosing spondylitis patients undergoing TNF-α antagonist therapy., PMID:23484462
Apelin in epiretinal fibrovascular membranes of patients with retinopathy of prematurity and the changes after intravitreal bevacizumab., PMID:23296045
Involvement of the apelin receptor APJ in Fas-induced liver injury., PMID:23121371
[Pathological role of apelin in angiogenic eye disease]., PMID:21804324
Emerging role of apelin as a therapeutic target in cancer: a patent review., PMID:21612576
Apelin-transgenic mice exhibit a resistance against diet-induced obesity by increasing vascular mass and mitochondrial biogenesis in skeletal muscle., PMID:21609753
Effects of apelin and vascular endothelial growth factor on central retinal vein occlusion in monkey eyes intravitreally injected with bevacizumab: a preliminary study., PMID:21552499
Nephropathy associated with antiphospholipid antibodies in patients with systemic lupus erythematosus., PMID:21486929
Vitreous and plasma concentrations of apelin and vascular endothelial growth factor after intravitreal bevacizumab in eyes with proliferative diabetic retinopathy., PMID:20890241
Apelin mediates the induction of profibrogenic genes in human hepatic stellate cells., PMID:20843995
Apelin in plasma and vitreous and in fibrovascular retinal membranes of patients with proliferative diabetic retinopathy., PMID:20220056
Involvement of a Stat3 binding site in inflammation-induced enteric apelin expression., PMID:18818315
A putative role for apelin in the etiology of obesity., PMID:18275845
Requirement of apelin-apelin receptor system for oxidative stress-linked atherosclerosis., PMID:17884970
Apelin stimulates myosin light chain phosphorylation in vascular smooth muscle cells., PMID:16556853
The endogenous peptide apelin potently improves cardiac contractility and reduces cardiac loading in vivo., PMID:15621035
Functional dissociation of apelin receptor signaling and endocytosis: implications for the effects of apelin on arterial blood pressure., PMID:15341513
Apelin, a potent diuretic neuropeptide counteracting vasopressin actions through inhibition of vasopressin neuron activity and vasopressin release., PMID:15231996
Dehydration-induced cross-regulation of apelin and vasopressin immunoreactivity levels in magnocellular hypothalamic neurons., PMID:15166125
Immunocytochemical localization of the endogenous vasoactive peptide apelin to human vascular and endocardial endothelial cells., PMID:15003827
Physiological role of a novel neuropeptide, apelin, and its receptor in the rat brain., PMID:11359874
Molecular properties of apelin: tissue distribution and receptor binding., PMID:11336787
Expression and coreceptor function of APJ for primate immunodeficiency viruses., PMID:11040134
For research use only. Not for human or drug use.
