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Anti-Human SPINK1 Antibody (SAA1736)

Catalog #:   RHB89301 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: ELISA
Accession: P00995
Overview

Catalog No.

RHB89301

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

TATI, Serine protease inhibitor Kazal-type 1, PSTI, Pancreatic secretory trypsin inhibitor, Tumor-associated trypsin inhibitor, SPINK1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P00995

Applications

ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA1736

Data Image
References

SPINK1-induced tumor plasticity provides a therapeutic window for chemotherapy in hepatocellular carcinoma., PMID:38030644

Serine Protease Inhibitor Kazal Type 1, A Potential Biomarker for the Early Detection, Targeting, and Prediction of Response to Immune Checkpoint Blockade Therapies in Hepatocellular Carcinoma., PMID:35924241

The Clinical Utility of Soluble Serum Biomarkers in Autoimmune Pancreatitis: A Systematic Review., PMID:35884816

SPINK1 as a plasma marker for tumor hypoxia and a therapeutic target for radiosensitization., PMID:34747365

A mouse testis serine protease, TESP1, as the potential SPINK3 receptor protein on mouse sperm acrosome., PMID:34524424

Targeting an autocrine IL-6-SPINK1 signaling axis to suppress metastatic spread in ovarian clear cell carcinoma., PMID:32929152

Tumor-associated trypsin inhibitor (TATI) and tumor-associated trypsin-2 (TAT-2) predict outcomes in gastric cancer., PMID:32124669

PRSS contributes to cetuximab resistance in colorectal cancer., PMID:31911942

Pseudogene Associated Recurrent Gene Fusion in Prostate Cancer., PMID:31446281

Inflammation and pancreatic cancer: An updated review., PMID:30588953

Screening of biomarkers for liver adenoma in low-dose-rate γ-ray-irradiated mice., PMID:29424599

The Diagnostic Role of SPINK1 in Differentiating Hepatocellular Carcinoma From Nonmalignant Lesions., PMID:27028242

Biomarker development, from bench to bedside., PMID:26287282

Prostate adenocarcinomas aberrantly expressing p63 are molecularly distinct from usual-type prostatic adenocarcinomas., PMID:25216229

Novel RNA hybridization method for the in situ detection of ETV1, ETV4, and ETV5 gene fusions in prostate cancer., PMID:25203299

[New biomarkers in prostate cancer]., PMID:24246875

Pancreatic secretory trypsin inhibitor causes autocrine-mediated migration and invasion in bladder cancer and phosphorylates the EGF receptor, Akt2 and Akt3, and ERK1 and ERK2., PMID:23698120

The clinical picture of juvenile parotitis in a prospective setup., PMID:22924783

Validation and comparison of tumor-associated trypsin inhibitor (TATI) immunoassays., PMID:22507084

Role of the inflammatory protein serine protease inhibitor Kazal in preventing cytolytic granule granzyme A-mediated apoptosis., PMID:22043941

Combined genomic and phenotype screening reveals secretory factor SPINK1 as an invasion and survival factor associated with patient prognosis in breast cancer., PMID:21656687

Therapeutic targeting of SPINK1-positive prostate cancer., PMID:21368222

Interference with the 19S proteasomal regulatory complex subunit PSMD4 on the sperm surface inhibits sperm-zona pellucida penetration during porcine fertilization., PMID:20526895

Exclusive expression of a membrane-bound Spink3-interacting serine protease-like protein TESPL in mouse testis., PMID:20512923

Autoantibodies against the exocrine pancreas in autoimmune pancreatitis: gene and protein expression profiling and immunoassays identify pancreatic enzymes as a major target of the inflammatory process., PMID:20407433

Expression and localization of acrosin inhibitor in boar reproductive tract., PMID:19813026

Analysis of humoral immune response in experimental autoimmune pancreatitis in mice., PMID:19812526

Pancreatic secretory trypsin inhibitor is a major motogenic and protective factor in human breast milk., PMID:19147803

Concomitant autoimmune and genetic pancreatitis leads to severe inflammatory conditions., PMID:18442214

Inhibition of a novel sperm gelatinase in prawn sperm by the male reproduction-related Kazal-type peptidase inhibitor., PMID:18324674

Autocrine induction of invasion and metastasis by tumor-associated trypsin inhibitor in human colon cancer cells., PMID:18317448

Human pancreatic secretory trypsin inhibitor stabilizes intestinal mucosa against noxious agents., PMID:17982125

Epitope topology and removal of mouse acrosomal plasma membrane by P12-targeted immunoaggregation., PMID:16934746

Identification of a novel autoantibody against pancreatic secretory trypsin inhibitor in patients with autoimmune pancreatitis., PMID:16804408

Preoperative serum hCGbeta as a prognostic marker in primary fallopian tube carcinoma., PMID:16340249

Trypsin-2 degrades human type II collagen and is expressed and activated in mesenchymally transformed rheumatoid arthritis synovitis tissue., PMID:16192646

High tissue expression of tumour-associated trypsin inhibitor (TATI) associates with a more favourable prognosis in gastric cancer., PMID:15810949

Identification of genes up-regulated in urothelial tumors: the 67-kd laminin receptor and tumor-associated trypsin inhibitor., PMID:12875970

Functional analysis of Toxoplasma gondii protease inhibitor 1., PMID:12228242

[Usefulness of selected circulating biochemical markers in diagnosis and monitoring of endometriosis]., PMID:10390920

Monitor peptide (rat pancreatic secretory trypsin inhibitor) directly stimulates the proliferation of the nontransformed intestinal epithelial cell line, IEC-6., PMID:9693203

Characterization of engineered hepatitis C virus NS3 protease inhibitors affinity selected from human pancreatic secretory trypsin inhibitor and minibody repertoires., PMID:9311825

Distribution and expression of pancreatic secretory trypsin inhibitor and its possible role in epithelial restitution., PMID:8774127

Pancreatic secretory trypsin inhibitor in human Brunner's glands., PMID:7719422

Modeling of protein loops by simulated annealing., PMID:8401234

Optimization of a time-resolved immunofluorometric assay for tumor-associated trypsin inhibitor (TATI) using the streptavidin-biotin system., PMID:8486933

Quantification of pancreatic secretory trypsin inhibitor in colonic carcinoma and normal adjacent colonic mucosa., PMID:1479031

Evaluation of CEA, CA 19-9, CA-50, CA-195, and TATI with special reference to pancreatic disorders., PMID:1791319

Tumor-associated trypsin inhibitor in induced and acquired immunodeficiency. Studies on transplanted and HIV-infected patients., PMID:1780693

Tumor-associated trypsin inhibitor as a possible marker in male infertility., PMID:1780692

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1640

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For research use only. Not for human or drug use.

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Anti-Human SPINK1 Antibody (SAA1736) [RHB89301]
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