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Anti-Human IFNAR2 Antibody (SAA1733)

Catalog #:   RHE59001 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: ELISA
Accession: P48551
Overview

Catalog No.

RHE59001

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

Interferon alpha binding protein, Interferon alpha/beta receptor 2, IFNAR2, IFN-alpha binding protein, IFN-R-2, IFNABR, IFNARB, Type I interferon receptor 2, IFN-alpha/beta receptor 2

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P48551

Applications

ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA1733

Data Image
References

Intestinal mucosal transcriptomic responses of Asian seabass (Lates calcarifer) vaccinated with an oral hydrogel-encapsulated multivalent Vibrio antigen following Vibrio spp. infection., PMID:40252617

Type I interferon autoantibody footprints reveal neutralizing mechanisms and allow inhibitory decoy design., PMID:40111224

A sensitive assay for measuring whole-blood responses to type I IFNs., PMID:39312669

Structural basis for the recognition of IFNAR1 by the humanized therapeutic monoclonal antibody QX006N for the treatment of systemic lupus erythematosus., PMID:38649079

Rickettsia rickettsii virulence determinants RARP2 and RapL mitigate IFN-β signaling in primary human dermal microvascular endothelial cells., PMID:38445878

Differential expression of Type I interferon and inflammatory genes in SARS-CoV-2-infected patients treated with monoclonal antibodies., PMID:37904704

Severity of SARS-CoV-2 infection in children with inborn errors of immunity (primary immunodeficiencies): a systematic review., PMID:37559153

A natural goldmine of binding proteins and soluble receptors simplified their translation to blockbuster drugs, all in one decade., PMID:36875111

Rubella Virus Triggers Type I Interferon Antiviral Response in Cultured Human Neural Cells: Involvement in the Control of Viral Gene Expression and Infectious Progeny Production., PMID:36077193

Defining resistance and tolerance traits in Covid-19: towards a stratified medicine approach., PMID:35686910

Implicating effector genes at COVID-19 GWAS loci using promoter-focused Capture-C in disease-relevant immune cell types., PMID:35659055

Inflammasome activation in infected macrophages drives COVID-19 pathology., PMID:35483404

Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever live attenuated vaccine., PMID:33544838

Role of Host Immune and Inflammatory Responses in COVID-19 Cases with Underlying Primary Immunodeficiency: A Review., PMID:33337932

Lactobacillus rhamnosus GG alleviates β-conglycinin-induced allergy by regulating the T cell receptor signaling pathway., PMID:33185639

Acute activation of bronchopulmonary vagal nociceptors by type I interferons., PMID:32924209

Anifrolumab in systemic lupus erythematosus: current knowledge and future considerations., PMID:32237942

Identification of Interferon Receptor IFNAR2 As a Novel HCV Entry Factor by Using Chemical Probes., PMID:31972076

Trial of Anifrolumab in Active Systemic Lupus Erythematosus., PMID:31851795

Genetic Diversity of Collaborative Cross Mice Controls Viral Replication, Clinical Severity, and Brain Pathology Induced by Zika Virus Infection, Independently of Oas1b., PMID:31694939

Anti-interferon-α receptor 1 antibodies attenuate inflammation and organ injury following hemorrhagic shock., PMID:31009444

CRISPR/Cas9 knockout of USP18 enhances type I IFN responsiveness and restricts HIV-1 infection in macrophages., PMID:29437254

Type-I interferon signalling through IFNAR1 plays a deleterious role in the outcome after stroke., PMID:28647375

Soybean-derived Bowman-Birk Inhibitor (BBI) Inhibits HIV Replication in Macrophages., PMID:27734899

Decreased soluble IFN-β receptor (sIFNAR2) in multiple sclerosis patients: A potential serum diagnostic biomarker., PMID:27613121

Interferon Beta: From Molecular Level to Therapeutic Effects., PMID:27572132

The bovine endometrial epithelial cells promote the differentiation of trophoblast stem-like cells to binucleate trophoblast cells., PMID:27473847

Endothelial progenitor dysfunction associates with a type I interferon signature in primary antiphospholipid syndrome., PMID:27432357

Renal microRNA- and RNA-profiles in progressive chronic kidney disease., PMID:26707063

Development of Th17-Associated Interstitial Kidney Inflammation in Lupus-Prone Mice Lacking the Gene Encoding STAT-1., PMID:26636548

Cytokine Activation by Antibody Fragments Targeted to Cytokine-Receptor Signaling Complexes., PMID:26546677

Virus Multiplicity of Infection Affects Type I Interferon Subtype Induction Profiles and Interferon-Stimulated Genes., PMID:26355085

Structural basis of the broadly neutralizing anti-interferon-α antibody rontalizumab., PMID:26099203

A fully human monoclonal antibody with novel binding epitope and excellent neutralizing activity to multiple human IFN-α subtypes: A candidate therapy for systemic lupus erythematosus., PMID:26048268

TNF-α Induced by Hepatitis C Virus via TLR7 and TLR8 in Hepatocytes Supports Interferon Signaling via an Autocrine Mechanism., PMID:26023919

Structural Insights into the Neutralization Properties of the Fully Human, Anti-interferon Monoclonal Antibody Sifalimumab., PMID:25925951

Molecular basis for antagonistic activity of anifrolumab, an anti-interferon-α receptor 1 antibody., PMID:25606664

Development of an in vitro model for the analysis of bovine endometrium using simple techniques., PMID:25496024

Cumulus cell-expressed type I interferons induce cumulus expansion in mice., PMID:25429090

Production and characterization of thirteen human type-I interferon-α subtypes., PMID:25149396

Single-nucleotide polymorphism associations in common with immune responses to measles and rubella vaccines., PMID:25139337

Critical role of interferon-α constitutively produced in human hepatocytes in response to RNA virus infection., PMID:24587086

High efficiency cell-specific targeting of cytokine activity., PMID:24398568

Luteolin sensitizes the antiproliferative effect of interferon α/β by activation of Janus kinase/signal transducer and activator of transcription pathway signaling through protein kinase A-mediated inhibition of protein tyrosine phosphatase SHP-2 in cancer cells., PMID:24333668

Kinetic analysis of cytokine-mediated receptor assembly using engineered FC heterodimers., PMID:23703950

Expression of IFNAR2 mRNA in peripheral blood mononuclear cells of patients with HCV infection., PMID:22870788

Hepatitis B Virus Genotype B and High Expression of Interferon Alpha Receptor β Subunit are Associated With Better Response to Pegylated Interferon Alpha 2a in Chinese Patients With Chronic Hepatitis B Infection., PMID:22783345

Structural insights into a human anti-IFN antibody exerting therapeutic potential for systemic lupus erythematosus., PMID:22307521

LPS regulates SOCS2 transcription in a type I interferon dependent autocrine-paracrine loop., PMID:22291912

Interleukin-22: implications for liver ischemia-reperfusion injury., PMID:22262131

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1640

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For research use only. Not for human or drug use.

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Anti-Human IFNAR2 Antibody (SAA1733) [RHE59001]
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