Catalog No.
RHG16201
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
Basement membrane autoantigen p105, Galectin-3-binding protein, MAC2BP, Mac-2 BP, M2BP, Mac-2-binding protein, Tumor-associated antigen 90K, Lectin galactoside-binding soluble 3-binding protein, LGALS3BP
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q08380
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1662
LGALS3BP antibody-drug conjugate enhances tumor-infiltrating lymphocytes and synergizes with immunotherapy to restrain neuroblastoma growth., PMID:40217513
Secreted LGALS3BP facilitates distant metastasis of breast cancer., PMID:39789641
Galectin-3-Binding Protein Inhibits Extracellular Heparan 6-O-Endosulfatase Sulf-2., PMID:38825040
Anti-LGALS3BP antibody-drug conjugate treatment induces durable and potent antitumor response in a preclinical model of adenoid cystic carcinoma., PMID:37988837
LGALS3BP is a potential target of antibody-drug conjugates in oral squamous cell carcinoma., PMID:37649401
Extracellular LGALS3BP: a potential disease marker and actionable target for antibody-drug conjugate therapy in glioblastoma., PMID:37195369
Visualizing Galectin-3 Binding Protein Expression with ImmunoPET., PMID:37191353
Antibody-mediated blockade for galectin-3 binding protein in tumor secretome abrogates PDAC metastasis., PMID:35858411
Human herpesvirus infections and circulating microvesicles expressing galectin-3 binding protein in patients with systemic lupus erythematosus., PMID:34874835
High-resolution serum proteome trajectories in COVID-19 reveal patient-specific seroconversion., PMID:34232570
SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care., PMID:34099652
Targeting Vesicular LGALS3BP by an Antibody-Drug Conjugate as Novel Therapeutic Strategy for Neuroblastoma., PMID:33076448
Surface-enhanced Raman scattering (SERS)-based immunosystem for ultrasensitive detection of the 90K biomarker., PMID:32875368
Stimulation of Mononuclear Cells Through Toll-Like Receptor 9 Induces Release of Microvesicles Expressing Double-Stranded DNA and Galectin 3-Binding Protein in an Interferon-α-Dependent Manner., PMID:31681284
A Targeted Mass Spectrometry Strategy for Developing Proteomic Biomarkers: A Case Study of Epithelial Ovarian Cancer., PMID:31289117
Secreted Gal-3BP is a novel promising target for non-internalizing Antibody-Drug Conjugates., PMID:30553852
Surfaceome profiling enables isolation of cancer-specific exosomal cargo in liquid biopsies from pancreatic cancer patients., PMID:29045505
Prediction of Response to Sorafenib in Hepatocellular Carcinoma: A Putative Marker Panel by Multiple Reaction Monitoring-Mass Spectrometry (MRM-MS)., PMID:28550167
Humoral markers of active Epstein-Barr virus infection associate with anti-extractable nuclear antigen autoantibodies and plasma galectin-3 binding protein in systemic lupus erythematosus., PMID:27084029
Galectin-3 binding protein links circulating microparticles with electron dense glomerular deposits in lupus nephritis., PMID:25837289
Inhibition of tumor growth and angiogenesis by SP-2, an anti-lectin, galactoside-binding soluble 3 binding protein (LGALS3BP) antibody., PMID:24552775
LGALS3BP, lectin galactoside-binding soluble 3 binding protein, promotes oncogenic cellular events impeded by antibody intervention., PMID:24362527
Circulating autoantibodies to LGALS3BP: a novel biomarker for cancer., PMID:24347795
Immunohistochemical analysis of medullary breast carcinoma autoantigens in different histological types of breast carcinomas., PMID:23181716
Cyclophilin C-associated protein regulation of phagocytic functions via NFAT activation in macrophages., PMID:21435337
Galectin-3-binding protein: a serological and histological assessment in accordance with hepatitis C-related liver fibrosis., PMID:20186066
Regulation of IFN response gene activity during infliximab treatment in rheumatoid arthritis is associated with clinical response to treatment., PMID:20096109
Cyclophilin C-associated protein/Mac-2 binding protein colocalizes with calnexin and regulates the expression of tissue transglutaminase., PMID:20049854
Galectin-3 expression in pouchitis in patients with ulcerative colitis who underwent ileal pouch-anal anastomosis (IPAA)., PMID:19278794
Identification of galectin-3-binding protein as a factor secreted by tumor cells that stimulates interleukin-6 expression in the bone marrow stroma., PMID:18450743
Identification of antigenic epitopes recognized by Mac-2 binding protein-specific cytotoxic T lymphocytes for use in cancer immunotherapy., PMID:15094380
Expression and immunogenicity of a tumor-associated antigen, 90K/Mac-2 binding protein, in lung carcinoma., PMID:12404290
Serum 90K/MAC-2BP glycoprotein in patients with liver cirrhosis and hepatocellular carcinoma: a comparison with alpha-fetoprotein., PMID:11758611
Serum protein 90K/Mac-2BP is an independent predictor of disease severity during hepatitis C virus infection., PMID:10905755
Concentrations of galectin-3 in the sera of normal controls and cancer patients., PMID:10778968
Monoclonal antibodies specific for human tumor-associated antigen 90K/Mac-2 binding protein: tools to examine protein conformation and function., PMID:10771511
Serum 90K/MAC-2BP glycoprotein levels in hepatocellular carcinoma and cirrhosis., PMID:10629637
Characterization of aggregates of hepatitis C virus glycoproteins., PMID:10567640
Mac-2 binding protein is a cell-adhesive protein of the extracellular matrix which self-assembles into ring-like structures and binds beta1 integrins, collagens and fibronectin., PMID:9501082
Identification of the tumor antigen 90K domains recognized by monoclonal antibodies SP2 and L3 and preparation and characterization of novel anti-90K monoclonal antibodies., PMID:9125183
Interactions between galectin-3 and Mac-2-binding protein mediate cell-cell adhesion., PMID:8813152
Elevated serum levels of 90K/MAC-2 BP predict unresponsiveness to alpha-interferon therapy in chronic HCV hepatitis patients., PMID:8878784
The secreted tumor-associated antigen 90K is a potent immune stimulator., PMID:8034587
Cloning and expression of a mouse macrophage cDNA coding for a membrane glycoprotein of the scavenger receptor cysteine-rich domain family., PMID:8119883
CA 549 and SP2: new tumor markers in breast cancer., PMID:2283484
Measurement of a monoclonal-antibody-defined antigen (90K) in the sera of patients with ovarian cancer., PMID:3178164
Antibodies to 90 kilodalton glycoprotein in childhood and adolescent celiac disease: relationship to reticulin antibodies., PMID:3316587
Detection of antigens recognized by a novel monoclonal antibody in tissue and serum from patients with breast cancer., PMID:3516389
Autoantibodies to gliadin-binding 90 kDa glycoprotein in coeliac disease., PMID:3485069
IgM class antibodies to intercellular substance in massive cutaneous hyalinosis: occurrence and relation to antigluten and antihyalin antibodies., PMID:2578104
For research use only. Not for human or drug use.
