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Anti-Human VAMP2 Antibody (SAA1655)

Catalog #:   RHF56701 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: ELISA
Accession: P63027
Overview

Catalog No.

RHF56701

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

SYB2, Vesicle-associated membrane protein 2, Synaptobrevin-2, VAMP2, VAMP-2

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P63027

Applications

ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA1655

Data Image
References

Biofluid biomarker changes following treatment with sabirnetug (ACU193) in INTERCEPT-AD, a phase 1 trial in early Alzheimer's disease., PMID:39955261

Neutralization mechanism of human monoclonal antibodies against type B botulinum neurotoxin., PMID:39239735

Single-extracellular vesicle (EV) analyses validate the use of L1 Cell Adhesion Molecule (L1CAM) as a reliable biomarker of neuron-derived EVs., PMID:38868956

Evaluation of cerebrospinal fluid levels of synaptic vesicle protein, VAMP-2, across the sporadic Alzheimer's disease continuum., PMID:37898760

Separation of Single Core and Multicore Lytic Granules by Subcellular Fractionation and Immunoisolation., PMID:37106182

Biological and Immunological Characterization of a Functional L-HN Derivative of Botulinum Neurotoxin Serotype F., PMID:36977091

Localization of SNARE proteins in the brain and corpus allatum of Bombyx mori., PMID:36129568

Effects of Cyclosporine A and Adalimumab on the expression profiles histaminergic system-associated genes and microRNAs regulating these genes in HaCaT cells., PMID:35899934

Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets., PMID:35666870

Collagen IV-β1-Integrin Influences INS-1 Cell Insulin Secretion via Enhanced SNARE Protein Expression., PMID:35573663

Synuclein Regulates Synaptic Vesicle Clustering and Docking at a Vertebrate Synapse., PMID:34901020

Insulin-activated store-operated Ca2+ entry via Orai1 induces podocyte actin remodeling and causes proteinuria., PMID:34764278

Bemisia tabaci Vesicle-Associated Membrane Protein 2 Interacts with Begomoviruses and Plays a Role in Virus Acquisition., PMID:34359870

VAMPs sensitive to tetanus toxin are required for cortical granule exocytosis in mouse oocytes., PMID:34023392

Cross-linking mass spectrometry uncovers protein interactions and functional assemblies in synaptic vesicle membranes., PMID:33558502

Potential Protection Against Type 2 Diabetes in Obesity Through Lower CD36 Expression and Improved Exocytosis in β-Cells., PMID:32198214

Antibodies raised against aldehyde-fixed antigens improve sensitivity for postembedding electron microscopy., PMID:30703389

Nanobodies reveal an extra-synaptic population of SNAP-25 and Syntaxin 1A in hippocampal neurons., PMID:30466346

Synaptotagmin oligomerization is essential for calcium control of regulated exocytosis., PMID:30038018

In Situ Proximity Ligation Assay Reveals Co-Localization of Alpha-Synuclein and SNARE Proteins in Murine Primary Neurons., PMID:29623065

The in vitro detection of botulinum neurotoxin-cleaved endogenous VAMP is epitope-dependent., PMID:29373835

Proximity Ligation Assay to Study the GLUT4 Membrane Trafficking Machinery., PMID:29218528

Subdiffractional tracking of internalized molecules reveals heterogeneous motion states of synaptic vesicles., PMID:27810917

Increased Levels of Extracellular Microvesicle Markers and Decreased Levels of Endocytic/Exocytic Proteins in the Alzheimer's Disease Brain., PMID:27636840

VAMP2 is implicated in the secretion of antibodies by human plasma cells and can be replaced by other synaptobrevins., PMID:27616736

In vitro potency determination of botulinum neurotoxin B based on its receptor-binding and proteolytic characteristics., PMID:27032463

Characterization of VAMP2 in Schistosoma japonicum and the Evaluation of Protective Efficacy Induced by Recombinant SjVAMP2 in Mice., PMID:26641090

Use of Monoclonal Antibodies in the Sensitive Detection and Neutralization of Botulinum Neurotoxin Serotype B., PMID:26633496

Postsynaptic VAMP/Synaptobrevin Facilitates Differential Vesicle Trafficking of GluA1 and GluA2 AMPA Receptor Subunits., PMID:26488171

Development of human-like scFv-Fc antibodies neutralizing Botulinum toxin serotype B., PMID:26381852

Astrocyte VAMP3 vesicles undergo Ca2+ -independent cycling and modulate glutamate transporter trafficking., PMID:25864578

Functional characterization of botulinum neurotoxin serotype H as a hybrid of known serotypes F and A (BoNT F/A)., PMID:25731972

Identification of synaptosomal proteins binding to monomeric and oligomeric α-synuclein., PMID:25659148

Mice with experimental antiphospholipid syndrome display hippocampal dysfunction and a reduction of dendritic complexity in hippocampal CA1 neurones., PMID:25201289

Distribution of SNAP25, VAMP1 and VAMP2 in mature and developing deep cerebellar nuclei after estrogen administration., PMID:24534378

Unique substrate recognition mechanism of the botulinum neurotoxin D light chain., PMID:23963459

Vesicle size determines unitary exocytic properties and their sensitivity to sphingosine., PMID:23791846

Expression of synaptogyrin-1 in T1R2-expressing type II taste cells and type III taste cells of rat circumvallate taste buds., PMID:23636420

Single-axonal organelle analysis method reveals new protein-motor associations., PMID:23421679

Peptide hormone release monitored from single vesicles in "membrane lawns" of differentiated male pituitary cells: SNAREs and fusion pore widening., PMID:23372020

Forward transport of proteins in the plasma membrane of migrating cerebellar granule cells., PMID:23213239

Increased synaptophysin is involved in inflammation-induced heat hyperalgesia mediated by cyclin-dependent kinase 5 in rats., PMID:23056393

Amyotrophic lateral sclerosis-immunoglobulins selectively interact with neuromuscular junctions expressing P/Q-type calcium channels., PMID:21883225

Functional characterization of the essential tail anchor of the herpes simplex virus type 1 nuclear egress protein pUL34., PMID:21832006

Expression, localization, and functional role for synaptotagmins in pancreatic acinar cells., PMID:21636530

Glucose-dependent changes in SNARE protein levels in pancreatic β-cells., PMID:21285315

A label-free biosensor assay for botulinum neurotoxin B in food and human serum., PMID:21134347

The association of dynamin with synaptophysin regulates quantal size and duration of exocytotic events in chromaffin cells., PMID:20702699

[Conditional cell targeting and reversible synapse silencing to study neural circuits]., PMID:20297730

Stimulation of GLUT4 (glucose transporter isoform 4) storage vesicle formation by sphingolipid depletion., PMID:20085539

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1640

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For research use only. Not for human or drug use.

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Anti-Human VAMP2 Antibody (SAA1655) [RHF56701]
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