Catalog No.
RHE77601
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
hASH1, ASH1, Achaete-scute homolog 1, BHLHA46, ASH-1, ASCL1, Class A basic helix-loop-helix protein 46, HASH1, bHLHa46
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P50553
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1643
FOXA2 promotes metastatic competence in small cell lung cancer., PMID:40419484
Molecular subtyping dictates therapeutic response to anti-PD-L1 immunotherapy in ES-SCLC., PMID:40402312
The Potential of Single-Transcription Factor Gene Expression by RT-qPCR for Subtyping Small Cell Lung Cancer., PMID:39941061
Dual onsets of small cell lung cancer with contrasting neuroendocrine features and immune microenvironments: A case report., PMID:39919549
Assessment of targets of antibody drug conjugates in SCLC., PMID:39748112
Relationship between the expressions of DLL3, ASC1, TTF-1 and Ki-67: First steps of precision medicine at SCLC., PMID:39392394
A Newly Developed Anti-L1CAM Monoclonal Antibody Targets Small Cell Lung Carcinoma Cells., PMID:39201435
Extensive-stage small-cell lung cancer in patients receiving atezolizumab plus carboplatin-etoposide: stratification of outcome based on a composite score that combines gene expression profiling and immune characterization of microenvironment., PMID:38955418
DLL3-guided therapies in small-cell lung cancer: from antibody-drug conjugate to precision immunotherapy and radioimmunotherapy., PMID:38730427
Neuroendocrine and squamous cell phenotypes of NUT carcinoma are potential diagnostic pitfalls that discriminating it from mimickers, such as small cell and squamous cell carcinoma., PMID:38326851
Pathologic diagnosis of lung cancer - recent developments., PMID:37975321
Identification of Lineage-specific Transcriptional Factor-defined Molecular Subtypes in Small Cell Bladder Cancer., PMID:37380560
Whole-Section Landscape Analysis of Molecular Subtypes in Curatively Resected Small Cell Lung Cancer: Clinicopathologic Features and Prognostic Significance., PMID:37054974
Identification of inflamed-phenotype of small cell lung cancer leading to the efficacy of anti-PD-L1 antibody and chemotherapy., PMID:37037178
NDR1 activates CD47 transcription by increasing protein stability and nuclear location of ASCL1 to enhance cancer stem cell properties and evasion of phagocytosis in small cell lung cancer., PMID:36224405
Immune Checkpoint Blockade Outcome in Small-Cell Lung Cancer and Its Relationship With Retinoblastoma Mutation Status and Function., PMID:36044718
Identification of Genes Predicting Poor Response of Trastuzumab in Human Epidermal Growth Factor Receptor 2 Positive Breast Cancer., PMID:35935587
A single factor elicits multilineage reprogramming of astrocytes in the adult mouse striatum., PMID:35254903
Molecular subtypes of small cell lung cancer transformed from adenocarcinoma after EGFR tyrosine kinase inhibitor treatment., PMID:35004251
Initiation of Otx2 expression in the developing mouse retina requires a unique enhancer and either Ascl1 or Neurog2 activity., PMID:34143204
Targeting netrin-3 in small cell lung cancer and neuroblastoma., PMID:33719214
Regulation of CEACAM5 and Therapeutic Efficacy of an Anti-CEACAM5-SN38 Antibody-drug Conjugate in Neuroendocrine Prostate Cancer., PMID:33199493
SCLC-CellMiner: A Resource for Small Cell Lung Cancer Cell Line Genomics and Pharmacology Based on Genomic Signatures., PMID:33086069
Molecular characterization of bovine amniotic fluid derived stem cells with an underlying focus on their comparative neuronal potential at different passages., PMID:31778790
Single-Cell RNA Sequencing of hESC-Derived 3D Retinal Organoids Reveals Novel Genes Regulating RPC Commitment in Early Human Retinogenesis., PMID:31543471
Autophagic death of neural stem cells mediates chronic stress-induced decline of adult hippocampal neurogenesis and cognitive deficits., PMID:31234698
Analysis of DLL3 and ASCL1 in Surgically Resected Small Cell Lung Cancer (HOT1702)., PMID:31068386
Notch pathway in small-cell lung cancer: from preclinical evidence to therapeutic challenges., PMID:30968324
Induction of human pluripotent stem cells into kidney tissues by synthetic mRNAs encoding transcription factors., PMID:30696889
Transdifferentiation effects and related mechanisms of nerve growth factor and internal limiting membrane on Müller cells., PMID:30578789
Transcriptomic and Protein Analysis of Small-cell Bladder Cancer (SCBC) Identifies Prognostic Biomarkers and DLL3 as a Relevant Therapeutic Target., PMID:30327311
Unravelling the biology of SCLC: implications for therapy., PMID:28534531
Partial Reprogramming of Pluripotent Stem Cell-Derived Cardiomyocytes into Neurons., PMID:28327614
Transfer of three transcription factors via a lentiviral vector ameliorates spatial learning and memory impairment in a mouse model of Alzheimer's disease., PMID:27102892
hASH1 is a specific immunohistochemical marker for lung neuroendocrine tumors., PMID:26596584
Primary Cilia on Horizontal Basal Cells Regulate Regeneration of the Olfactory Epithelium., PMID:26446227
NOTCH, ASCL1, p53 and RB alterations define an alternative pathway driving neuroendocrine and small cell lung carcinomas., PMID:26340530
Ascl1 controls the number and distribution of astrocytes and oligodendrocytes in the gray matter and white matter of the spinal cord., PMID:25249462
Lineage-reprogramming of pericyte-derived cells of the adult human brain into induced neurons., PMID:24893711
Analysis of DNA methylation reveals a partial reprogramming of the Müller glia genome during retina regeneration., PMID:24248357
Direct conversion of adipocyte progenitors into functional neurons., PMID:24182316
Targets in small cell lung cancer., PMID:24091017
Histone methyltransferase Ash1l suppresses interleukin-6 production and inflammatory autoimmune diseases by inducing the ubiquitin-editing enzyme A20., PMID:24012418
Induction of retinal ganglion-like cells from fibroblasts by adenoviral gene delivery., PMID:23856066
Prdm13 mediates the balance of inhibitory and excitatory neurons in somatosensory circuits., PMID:23639443
Loss of Gsx1 and Gsx2 function rescues distinct phenotypes in Dlx1/2 mutants., PMID:23042297
Human achaete-scute homolog-1 expression in neuroendocrine breast carcinoma., PMID:22422124
Uncx regulates proliferation of neural progenitor cells and neuronal survival in the olfactory epithelium., PMID:20692344
Thymosin beta4 improves functional neurological outcome in a rat model of embolic stroke., PMID:20627173
Neurog2 controls the leading edge of neurogenesis in the mammalian retina., PMID:20144606
For research use only. Not for human or drug use.
