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Anti-Human CD53 Antibody (SAA1593)

Catalog #:   RHD33601 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: ELISA
Accession: P19397
Overview

Catalog No.

RHD33601

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

CD53, Tetraspanin-25, Leukocyte surface antigen CD53, Cell surface glycoprotein CD53, Tspan-25, TSPAN25, MOX44

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P19397

Applications

ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA1593

Data Image
References

Inhibition of CD53 Reduces the Formation of ROS-Induced Neutrophil Extracellular Traps and Protects Against Inflammatory Injury in Acute Pancreatitis., PMID:40098997

PARP14 and PARP9/DTX3L regulate interferon-induced ADP-ribosylation., PMID:38834853

Tetraspanin CD53 regulates peripheral blood leucocytes vitality and pathogen infection in turbot (Scophthalmus maximus)., PMID:38296007

Canine Mammary Neoplasia Induces Variations in the Peripheral Blood Levels of CD20, CD45RA, and CD99., PMID:37298173

Unraveling the surface proteomic profile of multiple myeloma to reveal new immunotherapeutic targets and markers of drug resistance., PMID:36311892

Identification of Key Biomarkers and Immune Infiltration in Liver Tissue after Bariatric Surgery., PMID:35789605

Tetraspanin CD53 modulates lymphocyte trafficking but not systemic autoimmunity in Lyn-deficient mice., PMID:34514627

Immunopolymer Lipid Nanoparticles for Delivery of Macromolecules to Antigen-Expressing Cells., PMID:35019618

The regulation and function of CD20: an "enigma" of B-cell biology and targeted therapy., PMID:32482755

Surfaceome interrogation using an RNA-seq approach highlights leukemia initiating cell biomarkers in an LMO2 T cell transgenic model., PMID:30962539

Non-IgE mediated mast cell activation., PMID:29431205

Ibrutinib and idelalisib block immunophenotypic changes associated with the adhesion and activation of CLL cells in the tumor microenvironment., PMID:29164976

Tetraspanin microdomains control localized protein kinase C signaling in B cells., PMID:28487417

Tetraspanins and Transmembrane Adaptor Proteins As Plasma Membrane Organizers-Mast Cell Case., PMID:27243007

The tetraspanin CD53 modulates responses from activating NK cell receptors, promoting LFA-1 activation and dampening NK cell effector functions., PMID:24832104

Tetraspanins: Small transmembrane proteins with big impact on membrane microdomain structures., PMID:19704780

CD63 is not required for production of infectious human immunodeficiency virus type 1 in human macrophages., PMID:18321974

All-trans retinoic acid induces different immunophenotypic changes on human HL60 and NB4 myeloid leukaemias., PMID:17561254

Automation of semen analysis using flow cytometer in comparison with manual methods., PMID:16734137

Phenotypic characterization of regulatory CD4+CD25+ T cells in rats., PMID:14734622

Antigenic profile of human thymus in concurrence with "Clusters of Thymic Epithelial Staining" classification., PMID:12725440

Induction of DNA synthesis by ligation of the CD53 tetraspanin antigen in primary cultures of mesangial cells., PMID:12631118

Apoptosis protection and survival signal by the CD53 tetraspanin antigen., PMID:12606948

Immunophenotypic analysis of human spleen compartments., PMID:12392323

Apoptosis in human sperm: its correlation with semen quality and the presence of leukocytes., PMID:12351546

Transient activation of the c-Jun N-terminal kinase (JNK) activity by ligation of the tetraspan CD53 antigen in different cell types., PMID:11846804

Murine CD9 is the receptor for pregnancy-specific glycoprotein 17., PMID:11805154

Transmembrane-4 superfamily proteins associate with activated protein kinase C (PKC) and link PKC to specific beta(1) integrins., PMID:11325968

Anti-CD81 activates LFA-1 on T cells and promotes T cell-B cell collaboration., PMID:11241287

Targeted inactivation of the tetraspanin CD37 impairs T-cell-dependent B-cell response under suboptimal costimulatory conditions., PMID:10891477

Leukocyte detection in human semen using flow cytometry., PMID:10831564

Increased expression of the tetraspanins CD53 and CD63 on apoptotic human neutrophils., PMID:10733097

A general approach to the generation of monoclonal antibodies against members of the tetraspanin superfamily using recombinant GST fusion proteins., PMID:10556689

Functional expression of transmembrane 4 superfamily molecules on human eosinophils., PMID:10529602

Molecular characterization of U937-dependent T-cell co-stimulation., PMID:10233676

Selective tetraspan-integrin complexes (CD81/alpha4beta1, CD151/alpha3beta1, CD151/alpha6beta1) under conditions disrupting tetraspan interactions., PMID:10229664

Gamma-glutamyl transpeptidase, an ecto-enzyme regulator of intracellular redox potential, is a component of TM4 signal transduction complexes., PMID:9862348

Supramolecular receptor structures in the plasma membrane of lymphocytes revealed by flow cytometric energy transfer, scanning force- and transmission electron-microscopic analyses., PMID:9773884

Phenotypic characterization of human skin mast cells by combined staining with toluidine blue and CD antibodies., PMID:9764855

CD81 (TAPA-1): a molecule involved in signal transduction and cell adhesion in the immune system., PMID:9597125

Functional analysis of four tetraspans, CD9, CD53, CD81, and CD82, suggests a common role in costimulation, cell adhesion, and migration: only CD9 upregulates HB-EGF activity., PMID:9514697

Feline Langerhans cells migrate from skin and vaginal mucosa to regional lymph nodes during experimental contact sensitization with fluorescein isothiocyanate., PMID:34644954

NAG-2, a novel transmembrane-4 superfamily (TM4SF) protein that complexes with integrins and other TM4SF proteins., PMID:9360996

Generation of monoclonal antibodies to integrin-associated proteins. Evidence that alpha3beta1 complexes with EMMPRIN/basigin/OX47/M6., PMID:9360995

Ligation of CD53/OX44, a tetraspan antigen, induces homotypic adhesion mediated by specific cell-cell interactions., PMID:9225004

Anti-CD53 monoclonal antibody induced LFA-1/ICAM-1-dependent and -independent lymphocyte homotypic cell aggregation., PMID:9241532

The tetraspanin superfamily: molecular facilitators., PMID:9194523

Automation of human sperm cell analysis by flow cytometry., PMID:9166234

Supramolecular complexes of MHC class I, MHC class II, CD20, and tetraspan molecules (CD53, CD81, and CD82) at the surface of a B cell line JY., PMID:8816400

Transmembrane-4 superfamily proteins CD81 (TAPA-1), CD82, CD63, and CD53 specifically associated with integrin alpha 4 beta 1 (CD49d/CD29)., PMID:8757325

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1640

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Anti-Human CD53 Antibody (SAA1593) [RHD33601]
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