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Anti-Human CD97/ADGRE5 Antibody (SAA1566)

Catalog #:   RHE61901 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: ELISA, FCM
Accession: P48960
Overview

Catalog No.

RHE61901

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

ADGRE5, Adhesion G protein-coupled receptor E5, Leukocyte antigen CD97, CD97

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P48960

Applications

ELISA, FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

SAA1566

Data Image
References

CD97 maintains tumorigenicity of glioblastoma stem cells via mTORC2 signaling and is targeted by CAR Th9 cells., PMID:39637858

Modulation of GPR133 (ADGRD1) signaling by its intracellular interaction partner extended synaptotagmin 1., PMID:38758649

sBioSITe enables sensitive identification of the cell surface proteome through direct enrichment of biotinylated peptides., PMID:38053024

Dynamic encounters with red blood cells trigger splenic marginal zone B cell retention and function., PMID:38049580

The expression profile and tumorigenic mechanisms of CD97 (ADGRE5) in glioblastoma render it a targetable vulnerability., PMID:37938973

Dynamic Glycoprotein Hyposialylation Promotes Chemotherapy Evasion and Metastatic Seeding of Quiescent Circulating Tumor Cell Clusters in Breast Cancer., PMID:37272843

Targeting pediatric leukemia-propagating cells with anti-CD200 antibody therapy., PMID:34470052

Author Correction: G Protein-Coupling of Adhesion GPCRs ADGRE2/EMR2 and ADGRE5/CD97, and Activation of G Protein Signalling by an Anti-EMR2 Antibody., PMID:32184438

G Protein-Coupling of Adhesion GPCRs ADGRE2/EMR2 and ADGRE5/CD97, and Activation of G Protein Signalling by an Anti-EMR2 Antibody., PMID:31969668

Ibrutinib and idelalisib block immunophenotypic changes associated with the adhesion and activation of CLL cells in the tumor microenvironment., PMID:29164976

Detection of minimal residual disease in childhood B-acute lymphoblastic leukemia by 4-color flowcytometry., PMID:28324281

Membrane proteome analysis of glioblastoma cell invasion., PMID:25853691

Expression of B-cell-associated genes in peripheral blood mononuclear cells of patients with symptomatic pulmonary embolism., PMID:25411767

Triggering of the dsRNA sensors TLR3, MDA5, and RIG-I induces CD55 expression in synovial fibroblasts., PMID:22590509

F4/80 and the related adhesion-GPCRs., PMID:21952799

[Human CD96 gene cloning, expression and identification]., PMID:21764703

The cell surface proteome of human mesenchymal stromal cells., PMID:21637820

CD97 antibody depletes granulocytes in mice under conditions of acute inflammation via a Fc receptor-dependent mechanism., PMID:21169517

Oncoproteomic analysis reveals co-upregulation of RELA and STAT5 in carboplatin resistant ovarian carcinoma., PMID:20585448

Role of CD97 isoforms in gastric carcinoma., PMID:20428763

Decay-accelerating factor 1 (Daf1) deficiency exacerbates xenobiotic-induced autoimmunity., PMID:20408894

Deletion of either CD55 or CD97 ameliorates arthritis in mouse models., PMID:20131275

CD97 in leukocyte trafficking., PMID:21618832

Therapeutic antibody targeting of CD97 in experimental arthritis: the role of antigen expression, shedding, and internalization on the pharmacokinetics of anti-CD97 monoclonal antibody 1B2., PMID:19717518

Differential expression of CD97 on human lymphocyte subsets and limited effect of CD97 antibodies on allogeneic T-cell stimulation., PMID:19428565

Analysis of CD97 expression and manipulation: antibody treatment but not gene targeting curtails granulocyte migration., PMID:18941248

Differential role of CD97 in interleukin-8-induced and granulocyte-colony stimulating factor-induced hematopoietic stem and progenitor cell mobilization., PMID:18326527

CD97 neutralisation increases resistance to collagen-induced arthritis in mice., PMID:17007638

Costimulation via CD55 on human CD4+ T cells mediated by CD97., PMID:16818763

Decay-accelerating factor (CD55): a versatile acting molecule in human malignancies., PMID:16784816

Rapid leukocyte activation following intraarticular bleeding., PMID:16514634

Diversity of CD97 in smooth muscle cells., PMID:16408199

Dedicated pinhole SPECT of intestinal neutrophil recruitment in a mouse model of dextran sulfate sodium-induced colitis., PMID:15750169

Intact-protein-based high-resolution three-dimensional quantitative analysis system for proteome profiling of biological fluids., PMID:15703445

Identification of the epidermal growth factor-TM7 receptor EMR2 and its ligand dermatan sulfate in rheumatoid synovial tissue., PMID:15693006

Expression of the largest CD97 and EMR2 isoforms on leukocytes facilitates a specific interaction with chondroitin sulfate on B cells., PMID:15498814

N-glycosylation of CD97 within the EGF domains is crucial for epitope accessibility in normal and malignant cells as well as CD55 ligand binding., PMID:15386373

The epidermal growth factor-seven transmembrane (EGF-TM7) receptor CD97 is required for neutrophil migration and host defense., PMID:14707087

The epidermal growth factor-like domains of the human EMR2 receptor mediate cell attachment through chondroitin sulfate glycosaminoglycans., PMID:12829604

Enhanced expression of the complement regulatory protein CD55 predicts a poor prognosis in colorectal cancer patients., PMID:12811528

The human EGF-TM7 family member EMR2 is a heterodimeric receptor expressed on myeloid cells., PMID:11994511

CD97-decay-accelerating factor interaction is not involved in leukocyte adhesion to endothelial cells., PMID:11884941

Tissue distribution of the human CD97 EGF-TM7 receptor., PMID:11380941

Flt-1, vascular endothelial growth factor receptor 1, is a novel cell surface marker for the lineage of monocyte-macrophages in humans., PMID:11157498

Human EMR2, a novel EGF-TM7 molecule on chromosome 19p13.1, is closely related to CD97., PMID:10903844

Molecular cloning and characterization of mouse CD97., PMID:10744645

Decay accelerating factor (CD55): a target for cancer vaccines?, PMID:10344729

Expression of the activation antigen CD97 and its ligand CD55 in rheumatoid synovial tissue., PMID:10211878

Activation of peripheral blood T cells by interaction and migration through endothelium: role of lymphocyte function antigen-1/intercellular adhesion molecule-1 and interleukin-15., PMID:9920837

Phenotypic characterization of human skin mast cells by combined staining with toluidine blue and CD antibodies., PMID:9764855

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1640

Contact Information

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For research use only. Not for human or drug use.

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Anti-Human CD97/ADGRE5 Antibody (SAA1566) [RHE61901]
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