Catalog No.
RHA30901
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
TNFRSF10C, DCR1, TNF-related apoptosis-inducing ligand receptor 3, TRAILR3, DcR1, Decoy receptor 1, CD263, TRAIL receptor without an intracellular domain, Antagonist decoy receptor for TRAIL/Apo-2L, Decoy TRAIL receptor without death domain, Tumor necrosis factor receptor superfamily member 10C, LIT, Lymphocyte inhibitor of TRAIL, TRAIL-R3, TRID, TRAIL receptor 3
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
O14798
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1500
TRAIL regulatory receptors constrain human hepatic stellate cell apoptosis., PMID:28717244
Resveratrol sensitized leukemia stem cell-like KG-1a cells to cytokine-induced killer cells-mediated cytolysis through NKG2D ligands and TRAIL receptors., PMID:22406996
High TRAIL-R3 expression on leukemic blasts is associated with poor outcome and induces apoptosis-resistance which can be overcome by targeting TRAIL-R2., PMID:21281967
TRAIL receptor signalling and modulation: Are we on the right TRAIL?, PMID:19117685
TRAIL stimulates proliferation of vascular smooth muscle cells via activation of NF-kappaB and induction of insulin-like growth factor-1 receptor., PMID:18178561
Apoptotic phenotype alters the capacity of tumor necrosis factor-related apoptosis-inducing ligand to induce human vascular endothelial activation., PMID:17940338
The death receptor DR5 is involved in TRAIL-mediated human osteoclast apoptosis., PMID:17558561
Apoptosis resistance in ulcerative colitis: high expression of decoy receptors by lamina propria T cells., PMID:16856205
Expression of TRAIL and TRAIL receptors in normal and malignant tissues., PMID:15987601
Compartmentalization of TNF receptor 1 signaling: internalized TNF receptosomes as death signaling vesicles., PMID:15357952
Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs., PMID:15105837
The role of osteoprotegerin and tumor necrosis factor-related apoptosis-inducing ligand in human microvascular endothelial cell survival., PMID:15064358
Regulation of tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) and TRAIL receptor expression in human neutrophils., PMID:15027904
TNF-related apoptosis-inducing ligand is involved in neutropenia of systemic lupus erythematosus., PMID:15001474
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) and TNF-alpha promote the NF-kappaB-dependent maturation of normal and leukemic myeloid cells., PMID:12885939
Preparation and characterization of a set of monoclonal antibodies to TRAIL and TRAIL receptors DR4, DR5, DcR1, and DcR2., PMID:12831538
TRAIL induces death of human oligodendrocytes isolated from adult brain., PMID:12390973
Lack of tumor necrosis factor-related apoptosis-inducing ligand but presence of its receptors in the human brain., PMID:11844843
NO-mesalamine protects colonic epithelial cells against apoptotic damage induced by proinflammatory cytokines., PMID:11518677
Rel/NF-kappaB transcription factors protect against tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by up-regulating the TRAIL decoy receptor DcR1., PMID:11350953
TRAIL-induced apoptosis of thyroid cancer cells: potential for therapeutic intervention., PMID:10918593
Production of recombinant TRAIL and TRAIL receptor: Fc chimeric proteins., PMID:10914028
Functional analysis of TRAIL receptors using monoclonal antibodies., PMID:10072501
Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL., PMID:9603945
Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family., PMID:9314565
For research use only. Not for human or drug use.
