Catalog No.
YMN00101
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Ser21-Glu129
Predicted molecular weight
39.92 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
A8C1R4
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
G9D3 protein, Timd2
TIM2 modulates retinal iron levels and is involved in blood-retinal barrier breakdown., PMID:33065090
Targeting Myeloid-Derived Suppressor Cells Is a Novel Strategy for Anti-Psoriasis Therapy., PMID:32684837
Development of Timd2 as a reporter gene for MRI., PMID:25981669
The impact of the TIM gene family on tumor immunity and immunosuppression., PMID:24336162
T-cell immunoglobulin and mucin domain 2 (TIM-2) is a target of ADAM10-mediated ectodomain shedding., PMID:24164679
Neuroimmune semaphorin 4A as a drug and drug target for asthma., PMID:23994348
Tim-2 up-regulation and galectin-9-Tim-3 pathway activation in Th2-biased response in Schistosoma japonicum infection in mice., PMID:22469568
Iron uptake mediated by binding of H-ferritin to the TIM-2 receptor in mouse cells., PMID:21886823
Expression of neuroimmune semaphorins 4A and 4D and their receptors in the lung is enhanced by allergen and vascular endothelial growth factor., PMID:21595947
Anti-T cell immunoglobulin and mucin domain-2 monoclonal antibody exacerbates collagen-induced arthritis by stimulating B cells., PMID:21426565
TIM2 gene deletion results in susceptibility to cisplatin-induced kidney toxicity., PMID:20702592
Searching for novel intercellular signal-transducing molecules in the kidney and their clinical application., PMID:20652349
Tim-3-Galectin-9 pathway involves the suppression induced by CD4+CD25+ regulatory T cells., PMID:19362679
Tim-2 is the receptor for H-ferritin on oligodendrocytes., PMID:19014383
[Enhancing effect of matrine on the tumor-inhibition by TIM2 gene-modified hepatocarcinoma H22 cells in mice]., PMID:18788626
TIM gene family and their role in atopic diseases., PMID:18727494
[Effects of matrine on oncogenicity of H22 cells modified by TIM2 gene in vivo]., PMID:18720871
T-cell Ig and mucin domain-containing protein (Tim)-2 regulates murine allergic conjunctivitis during the effector phase., PMID:17532058
Tim2 is expressed in mouse fetal hepatocytes and regulates their differentiation., PMID:17465005
Tim protein structures reveal a unique face for ligand binding., PMID:17376389
Structures of T Cell immunoglobulin mucin receptors 1 and 2 reveal mechanisms for regulation of immune responses by the TIM receptor family., PMID:17363299
Epitope-dependent effect of anti-murine TIM-1 monoclonal antibodies on T cell activity and lung immune responses., PMID:17277130
Antibodies to T-cell Ig and mucin domain-containing proteins (Tim)-1 and -3 suppress the induction and progression of murine allergic conjunctivitis., PMID:17174273
Cutting edge: inhibition of T cell activation by TIM-2., PMID:17015678
Gene expression profile of the infective murine model for biliary atresia., PMID:16328331
TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosis., PMID:16203866
Regulation of T cell dependent immune responses by TIM family members., PMID:16147532
The cysteine-rich domain of the secreted proprotein convertases PC5A and PACE4 functions as a cell surface anchor and interacts with tissue inhibitors of metalloproteinases., PMID:16135528
Tim-2 regulates T helper type 2 responses and autoimmunity., PMID:16043519
The TIM gene family regulates autoimmune and allergic diseases., PMID:16002337
Immune semaphorins: a new area of semaphorin research., PMID:12893810
The TIM gene family: emerging roles in immunity and disease., PMID:12776205
Semaphorins in interactions between T cells and antigen-presenting cells., PMID:12563299
Class IV semaphorin Sema4A enhances T-cell activation and interacts with Tim-2., PMID:12374982
Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family., PMID:11725301
For research use only. Not for human or drug use.
