Catalog No.
YMK99001
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Gly43-Gly175
Predicted molecular weight
43.09 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P35230
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Pancreatitis-associated protein 1, REG-3-beta, Reg III-beta, Regenerating islet-derived protein III-beta, Reg3b, Pap1, Regenerating islet-derived protein 3-beta, Pap
2'-Fucosyllactose Modulates the Intestinal Immune Response to Gut Microbiota and Buffers Experimental Colitis in Mice: An Integrating Investigation of Colonic Proteomics and Gut Microbiota Analysis., PMID:40501496
Effects of the regenerating gene family on DSS-induced ulcerative colitis in a mouse model., PMID:40300333
Oral tributyrin treatment affects short-chain fatty acid transport, mucosal health, and microbiome in a mouse model of inflammatory diarrhea., PMID:39870330
Neuroinflammation signatures in dorsal root ganglia following chronic constriction injury., PMID:38813203
IL-22-dependent responses and their role during Citrobacter rodentium infection., PMID:38557196
Lactobacillus rhamnosus Probio-M9 alleviates OVA-sensitized food allergy through modulating gut microbiota and its metabolism., PMID:37982421
Bacillus subtilis pretreatment alleviates ethanol-induced acute liver injury by regulating the Gut-liver axis in mice., PMID:36907542
Global Transcriptomics of Congenital Hepatic Fibrosis in Autosomal Recessive Polycystic Kidney Disease using PCK rats., PMID:36711494
Dysregulated hepatic lipid metabolism and gut microbiota associated with early-stage NAFLD in ASPP2-deficiency mice., PMID:36466835
Changes in gut microbiome correlate with intestinal barrier dysfunction and inflammation following a 3-day ethanol exposure in aged mice., PMID:36150609
Role and mechanism of REG2 depletion in insulin secretion augmented by glutathione peroxidase-1 overproduction., PMID:36063729
Milk Fat Globule Membrane Attenuates Acute Colitis and Secondary Liver Injury by Improving the Mucus Barrier and Regulating the Gut Microbiota., PMID:35799795
Age and sex effects across the blood proteome after ionizing radiation exposure can bias biomarker screening and risk assessment., PMID:35487913
A short framework-III (mini-M-2) conotoxin from the venom of a vermivorous species, Conus archon, inhibits human neuronal nicotinic acetylcholine receptors., PMID:35307452
Psychological stress disrupts intestinal epithelial cell function and mucosal integrity through microbe and host-directed processes., PMID:35184677
Oxidized phospholipids cause changes in jejunum mucus that induce dysbiosis and systemic inflammation., PMID:34808192
Spared Nerve Injury Causes Sexually Dimorphic Mechanical Allodynia and Differential Gene Expression in Spinal Cords and Dorsal Root Ganglia in Rats., PMID:34331199
REG3A/REG3B promotes acinar to ductal metaplasia through binding to EXTL3 and activating the RAS-RAF-MEK-ERK signaling pathway., PMID:34099862
Molecular toxicological alterations in the mouse hearts induced by sub-chronic thiazolidinedione drugs administration., PMID:33969534
Helicobacter pylori-Induced Rev-erbα Fosters Gastric Bacteria Colonization by Impairing Host Innate and Adaptive Defense., PMID:33676046
Oral administration of PEGylated TLR7 ligand ameliorates alcohol-associated liver disease via the induction of IL-22., PMID:33443222
Microbiota-derived short chain fatty acid promotion of Amphiregulin expression by dendritic cells is regulated by GPR43 and Blimp-1., PMID:32958255
Distinct Effects of Milk-Derived and Fermented Dairy Protein on Gut Microbiota and Cardiometabolic Markers in Diet-Induced Obese Mice., PMID:32886125
Fructose stimulated de novo lipogenesis is promoted by inflammation., PMID:32839596
Intestinal microbiota transplantation reveals the role of microbiota in dietary regulation of RegIIIβ and RegIIIγ expression in mouse intestine., PMID:32560820
Reg3α and Reg3β Expressions Followed by JAK2/STAT3 Activation Play a Pivotal Role in the Acceleration of Liver Hypertrophy in a Rat ALPPS Model., PMID:32517345
HIP/PAP protects against bleomycin-induced lung injury and inflammation and subsequent fibrosis in mice., PMID:32352211
The effect of antibiotic cocktails on host immune status is dynamic and does not always correspond to changes in gut microbiota., PMID:32303819
Intestinal enteroids recapitulate the effects of short-chain fatty acids on the intestinal epithelium., PMID:32240190
Gut Microbiota-Derived Propionate Regulates the Expression of Reg3 Mucosal Lectins and Ameliorates Experimental Colitis in Mice., PMID:32227170
Lactobacillus reuteri 5454 and Bifidobacterium animalis ssp. lactis 5764 improve colitis while differentially impacting dendritic cells maturation and antimicrobial responses., PMID:32210304
Pancreatitis-associated protein-1 suppresses apoptosis in cerulein-stimulated pancreatic acinar cells in response to nuclear factor-kappa B activation., PMID:32084646
Regenerating islet-derived protein (Reg)3β plays a crucial role in attenuation of ileitis and colitis in mice., PMID:32072024
Melatonin controls microbiota in colitis by goblet cell differentiation and antimicrobial peptide production through Toll-like receptor 4 signalling., PMID:32042047
Retinoid acid induced 16 deficiency aggravates colitis and colitis-associated tumorigenesis in mice., PMID:31862898
Gastrointestinal (non-systemic) antibiotic rifaximin differentially affects chronic stress-induced changes in colon microbiome and gut permeability without effect on behavior., PMID:31821847
Nerve Injury-Induced Neuronal PAP-I Maintains Neuropathic Pain by Activating Spinal Microglia., PMID:31744864
Hepatocarcinoma-intestine-pancreas/pancreatitis-associated protein (HIP/PAP) confers protection against hepatic fibrosis through downregulation of transforming growth factor β receptor II., PMID:31641222
A20 in dendritic cells restrains intestinal anti-bacterial peptide expression and preserves commensal homeostasis., PMID:31295268
Wheat Germ Supplementation Increases Lactobacillaceae and Promotes an Anti-inflammatory Gut Milieu in C57BL/6 Mice Fed a High-Fat, High-Sucrose Diet., PMID:31162575
METTL14 is essential for β-cell survival and insulin secretion., PMID:31029827
Glutathione peroxidase-1 inhibits transcription of regenerating islet-derived protein-2 in pancreatic islets., PMID:30703484
Dimorphic autoantigenic and protective effects of Reg2 peptide in the treatment of diabetic β-cell loss., PMID:30690849
MiR-125b-2 Knockout in Testis Is Associated with Targeting to the PAP Gene, Mitochondrial Copy Number, and Impaired Sperm Quality., PMID:30609807
Lactobacillus salivarius reverse antibiotic-induced lung defense impairment in a ventilator model., PMID:30103798
Lipid malabsorption from altered hormonal signaling changes early gut microbial responses., PMID:29953253
Lactobacillus plantarum reverse diabetes-induced Fmo3 and ICAM expression in mice through enteric dysbiosis-related c-Jun NH2-terminal kinase pathways., PMID:29851956
Reg proteins direct accumulation of functionally distinct macrophage subsets after myocardial infarction., PMID:29850784
The Role of Intestinal C-type Regenerating Islet Derived-3 Lectins for Nonalcoholic Steatohepatitis., PMID:29619418
Reg3β is associated with cardiac inflammation and provides prognostic information in patients with acute coronary syndrome., PMID:29544958
For research use only. Not for human or drug use.
