Catalog No.
YMK98501
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Ser34-Lys202
Predicted molecular weight
21.65 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9CZQ6
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Retinoic acid early-inducible protein 1-epsilon, RAE-1-epsilon, Raet1e
Elucidating genetic and molecular basis of altered higher-order brain structure-function coupling in major depressive disorder., PMID:38971483
Characterisation of RAET1E/ULBP4 exon 4 and 3' untranslated region genetic architecture reveals further diversity and allelic polymorphism., PMID:38575368
β-catenin attenuation leads to up-regulation of activating NKG2D ligands and tumor regression in BrafV600E-driven thyroid cancer cells., PMID:37483610
A novel risk score based on immune-related genes for hepatocellular carcinoma as a reliable prognostic biomarker and correlated with immune infiltration., PMID:36353638
Immunoprognostic model of lung adenocarcinoma and screening of sensitive drugs., PMID:35504892
Identification of Immune Cells and Key Genes associated with Alzheimer's Disease., PMID:34975305
Stress Signal ULBP4, an NKG2D Ligand, Is Upregulated in Multiple Sclerosis and Shapes CD8+ T-Cell Behaviors., PMID:34873031
The whole profiling and competing endogenous RNA network analyses of noncoding RNAs in adipose-derived stem cells from diabetic, old, and young patients., PMID:34051854
The NKG2D ligand ULBP4 is not expressed by human monocytes., PMID:33556116
Transcriptomic analysis of micropapillary high grade T1 urothelial bladder cancer., PMID:33208770
Constitutive expression of ULBP-4 on monocytes regulates NK cell NKG2D expression., PMID:31097432
Raet1e Polymorphisms Are Associated with Increased Risk of Developing Premature Coronary Artery Disease and with Some Cardiometabolic Parameters: The GEA Mexican Study., PMID:30662365
Blockade of NKG2D/NKG2D ligand interaction attenuated cardiac remodelling after myocardial infarction., PMID:30307485
Cutting an NKG2D Ligand Short: Cellular Processing of the Peculiar Human NKG2D Ligand ULBP4., PMID:29651291
Hydroxychloroquine sensitizes chronic myeloid leukemia cells to Vγ9Vδ2 T cell-mediated lysis independent of autophagy., PMID:28339029
Decreased expression of the NKG2D ligand ULBP4 may be an indicator of poor prognosis in patients with nasopharyngeal carcinoma., PMID:28159927
NKG2D Signaling: The Immune Subversive Side of HDAC3., PMID:28089218
RAE-1 expression is induced during experimental autoimmune encephalomyelitis and is correlated with microglia cell proliferation., PMID:27444966
V-akt murine thymoma viral oncogene homolog 3 (AKT3) contributes to poor disease outcome in humans and mice with pneumococcal meningitis., PMID:27193124
Increasing polymorphism of the RAET1E/ULBP4 gene in humans., PMID:26814419
[An immunological approach to acute myeloid leukaemia]., PMID:26776165
Characterization of 5' promoter and exon 1-3 polymorphism of the RAET1E gene., PMID:26519211
NKG2D Receptor and Its Ligands in Host Defense., PMID:26041808
Exome analysis reveals differentially mutated gene signatures of stage, grade and subtype in breast cancers., PMID:25803781
MICA/B and ULBP1 NKG2D ligands are independent predictors of good prognosis in cervical cancer., PMID:25510288
Immunohistochemical validation and expression profiling of NKG2D ligands in a wide spectrum of human epithelial neoplasms., PMID:25473094
Further polymorphism of the RAET1E/ULBP4 gene in humans., PMID:24849594
CD4(+) NKG2D(+) T cells induce NKG2D down-regulation in natural killer cells in CD86-RAE-1ε transgenic mice., PMID:24708417
Cancer exosomes and NKG2D receptor-ligand interactions: impairing NKG2D-mediated cytotoxicity and anti-tumour immune surveillance., PMID:24602822
Effects on tumor development and metastatic dissemination by the NKG2D lymphocyte receptor expressed on cancer cells., PMID:24141776
TLR and NKG2D signaling pathways mediate CS-induced pulmonary pathologies., PMID:24130907
Genetics of common forms of heart disease: a long and winding road., PMID:24115066
Altered expression of Raet1e, a major histocompatibility complex class 1-like molecule, underlies the atherosclerosis modifier locus Ath11 10b., PMID:23948654
RAET1/ULBP alleles and haplotypes among Kolla South American Indians., PMID:23416094
RAE-1 ligands for the NKG2D receptor are regulated by E2F transcription factors, which control cell cycle entry., PMID:23166357
The genotype of RAET1L (ULBP6), a ligand for human NKG2D (KLRK1), markedly influences the clinical outcome of allogeneic stem cell transplantation., PMID:23025544
Three novel allelic variants of the RAET1E/ULBP4 gene in humans., PMID:22845659
Ras activation induces expression of Raet1 family NK receptor ligands., PMID:22798674
Cervical cancer cell lines expressing NKG2D-ligands are able to down-modulate the NKG2D receptor on NKL cells with functional implications., PMID:22316211
ULBP4/RAET1E is highly polymorphic in the Old World monkey., PMID:21553130
Linkage disequilibrium of polymorphic RAET1 genes in Thais., PMID:20522206
Murine trophoblast cells induce NK cell interferon-gamma production through KLRK1., PMID:20484740
Post-translational modification of the NKG2D ligand RAET1G leads to cell surface expression of a glycosylphosphatidylinositol-linked isoform., PMID:20304922
Chronic cigarette smoke exposure primes NK cell activation in a mouse model of chronic obstructive pulmonary disease., PMID:20228194
Single nucleotide polymorphism analysis of the NKG2D ligand cluster on the long arm of chromosome 6: Extensive polymorphisms and evidence of diversity between human populations., PMID:20219610
ULBP2 and RAET1E NKG2D ligands are independent predictors of poor prognosis in ovarian cancer patients., PMID:20054857
Polymorphisms of NKG2D ligands: diverse RAET1/ULBP genes in northeastern Thais., PMID:19688209
The NKG2D ligand ULBP4 binds to TCRgamma9/delta2 and induces cytotoxicity to tumor cells through both TCRgammadelta and NKG2D., PMID:19436053
Sustained CTL activation by murine pulmonary epithelial cells promotes the development of COPD-like disease., PMID:19197141
NKG2D-RAE-1 receptor-ligand variation does not account for the NK cell defect in nonobese diabetic mice., PMID:18981127
For research use only. Not for human or drug use.
