Catalog No.
YHC94901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp26-Arg232
Predicted molecular weight
25.90 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P12814
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Alpha-actinin cytoskeletal isoform, Non-muscle alpha-actinin-1, Alpha-actinin-1, ACTN1, F-actin cross-linking protein
A Genetic Perspective to Reveal the Impact of Mitochondrial Dysfunction-related Genes on Diabetic Kidney Disease: A Multi-omics Study., PMID:40464186
Differential Genes Analysis and Validation of Disulfideptosis in Rat Myocardial Ischemia-Reperfusion Injury Model., PMID:40323799
Identifying therapeutic target genes for diabetic retinopathy using systematic druggable genome-wide Mendelian randomization., PMID:40301928
Plasma Proteomics of the Fontan Circulation Reveal Signatures of Oxidative Stress and Cell Death., PMID:40235440
F-box only protein 25-mediated α-actinin 1 upregulation drives ovarian cancer progression via ERK1/2 signaling in tumor cells and macrophage M2 polarization., PMID:40117808
From inflammation to remodelling: A novel BASP1+ monocyte subset as a catalyst for acute aortic dissection., PMID:40057028
Structural and functional insights into α-actinin isoforms and their implications in cardiovascular disease., PMID:39918740
α-Actinin-1 deficiency in megakaryocytes causes low platelet count, platelet dysfunction, and mitochondrial impairment., PMID:39813624
4D-DIA Proteomics Uncovers New Insights into Host Salivary Response Following SARS-CoV-2 Omicron Infection., PMID:39803891
IL-33, a neutrophil extracellular trap-related gene involved in the progression of diabetic kidney disease., PMID:39797951
Circulating large extracellular vesicles as diagnostic biomarkers of indeterminate thyroid nodules: multi-platform omics analysis., PMID:39787026
ACTN1 promotes cell invasion, migration, and EMT in thyroid cancer and is associated with immune infiltration., PMID:39738470
Gene-expression profile analysis to disclose diagnostics and therapeutics biomarkers for thyroid carcinoma., PMID:39454454
Validation of a blood biomarker panel for machine learning-based radiation biodosimetry in juvenile and adult C57BL/6 mice., PMID:39396080
Exploring CD26-/lo subpopulations of lymphocytes in asthma phenotype and severity: A novel CD4+ T cell subset expressing archetypical granulocyte proteins., PMID:39319599
Functional Insights in PLS3-Mediated Osteogenic Regulation., PMID:39273077
Live-cell imaging and CLEM reveal the existence of ACTN4-dependent ruffle-edge lamellipodia acting as a novel mode of cell migration., PMID:39222868
Chemical shift assignments of the α-actinin C-terminal EF-hand domain bound to a cytosolic C0 domain of GluN1 (residues 841-865) from the NMDA receptor., PMID:39207574
Identification of molecular targets and small drug candidates for Huntington's disease via bioinformatics and a network-based screening approach., PMID:39153206
Identification of key genes involved in collagen hydrogel-induced chondrogenic differentiation of mesenchymal stem cells through transcriptome analysis: the role of m6A modification., PMID:39073623
Biomarkers for Radiation Biodosimetry and Correlation with Hematopoietic Injury in a Humanized Mouse Model., PMID:39034036
Loss of SIL1 Affects Actin Dynamics and Leads to Abnormal Neural Migration., PMID:38850350
ACTN1 promotes malignant progression in cutaneous squamous cell carcinoma by downregulating the p53 signaling pathway., PMID:38835108
Molecular mechanism analysis of nontuberculous mycobacteria infection in patients with cystic fibrosis., PMID:38700285
ACTN1-related thrombocytopenia: Homozygosity for an ACTN1 variant results in a more severe phenotype., PMID:38594875
Machine learning identifies novel coagulation genes as diagnostic and immunological biomarkers in ischemic stroke., PMID:38575196
miR-129-5p inhibits anchorage-independent growth through silencing of ACTN1 and the ELK4/c-FOS axis in HPV-transformed keratinocytes., PMID:38566572
Deciphering the omicron variant: integrated omics analysis reveals critical biomarkers and pathophysiological pathways., PMID:38424541
Transcriptome Data Revealed the circRNA-miRNA-mRNA Regulatory Network during the Proliferation and Differentiation of Myoblasts in Shitou Goose., PMID:38396545
Identification of EMT-associated prognostic features among grade II/III gliomas., PMID:38307919
Actinin-4 controls survival signaling in B cells by limiting the lateral mobility of B-cell antigen receptors., PMID:38299456
Metabotropic glutamate receptor 5 promotes blood-brain barrier recovery after traumatic brain injury., PMID:38224942
LLGL2 Inhibits Ovarian Cancer Metastasis by Regulating Cytoskeleton Remodeling via ACTN1., PMID:38136424
ACTN1 promotes HNSCC tumorigenesis and cisplatin resistance by enhancing MYH9-dependent degradation of GSK-3β and integrin β1-mediated phosphorylation of FAK., PMID:38057867
Colostrum Features of Active and Recovered COVID-19 Patients Revealed Using Next-Generation Proteomics Technique, SWATH-MS., PMID:37628421
Systematical analysis of underlying markers associated with Marfan syndrome via integrated bioinformatics and machine learning strategies., PMID:37449753
The value of ACTN1 in the diagnosis of cutaneous squamous cell carcinoma: A continuation study., PMID:37113080
Liquid biopsy-based protein biomarkers for risk prediction, early diagnosis, and prognostication of cholangiocarcinoma., PMID:36868481
ACTN1 interacts with ITGA5 to promote cell proliferation, invasion and epithelial-mesenchymal transformation in head and neck squamous cell carcinoma., PMID:36742137
Allogenic Adipose-Derived Stem Cells in Diabetic Foot Ulcer Treatment: Clinical Effectiveness, Safety, Survival in the Wound Site, and Proteomic Impact., PMID:36674989
Microcystin-LR exposure interfered maintenance of colonic microenvironmental homeostasis in rat., PMID:36657700
Machine learning approach for quantitative biodosimetry of partial-body or total-body radiation exposures by combining radiation-responsive biomarkers., PMID:36653416
An epithelial-mesenchymal transition-related prognostic model for colorectal cancer based on weighted gene co-expression network analysis., PMID:36510452
Scalable Generation of Nanovesicles from Human-Induced Pluripotent Stem Cells for Cardiac Repair., PMID:36430812
Relevant proteins for the monitoring of engraftment phases after allogeneic hematopoietic stem cell transplantation., PMID:36403426
Computer-Aided Imaging Analysis of Probe-Based Confocal Laser Endomicroscopy With Molecular Labeling and Gene Expression Identifies Markers of Response to Biological Therapy in IBD Patients: The Endo-Omics Study., PMID:36378498
Genetic Polymorphisms Associated with Prothrombin Time and Activated Partial Thromboplastin Time in Chinese Healthy Population., PMID:36292752
CGF-HLC-I repaired the bone defect repair of the rabbits mandible through tight junction pathway., PMID:36204467
Atomic force microscopy identifies the alteration of rheological properties of the cardiac fibroblasts in idiopathic restrictive cardiomyopathy., PMID:36174041
Bioinformatics analysis identification of AKT3 and RAC1 as key genes in postmenopausal osteoporosis., PMID:36168425
For research use only. Not for human or drug use.
