Catalog No.
YHK96101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro238-Leu327
Predicted molecular weight
22.62 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q5HYK3
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial, COQ5, Ubiquinone biosynthesis methyltransferase COQ5
Genomic insights into chlorine resistance of a Mycobacterium sp. strain isolated from treated wastewater effluent., PMID:40381280
Genetic Markers of Postmortem Brain Iron., PMID:39918201
Modelling the human coenzyme Q deficiency in Drosophila melanogaster., PMID:39864756
In vitro construction of the COQ metabolon unveils the molecular determinants of coenzyme Q biosynthesis., PMID:38425362
Congenital coenzyme Q5-linked pathology: causal genetic association, core phenotype, and molecular mechanism., PMID:37599337
Levels of Coenzyme Q10 and Several COQ Proteins in Human Astrocytoma Tissues Are Inversely Correlated with Malignancy., PMID:35204836
Mitochondrial autophagy and cell survival is regulated by the circadian Clock gene in cardiac myocytes during ischemic stress., PMID:34085589
ADCK4 Deficiency Destabilizes the Coenzyme Q Complex, Which Is Rescued by 2,4-Dihydroxybenzoic Acid Treatment., PMID:32381600
Characterization of human mitochondrial PDSS and COQ proteins and their roles in maintaining coenzyme Q10 levels and each other's stability., PMID:32194061
The kynurenine pathway is essential for rhodoquinone biosynthesis in Caenorhabditis elegans., PMID:31177094
Mitochondrial dysfunction in fibroblasts of Multiple System Atrophy., PMID:30254015
Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis., PMID:30228311
Suppression of respiratory growth defect of mutant deficient in mitochondrial phospholipase A1 by overexpression of genes involved in coenzyme Q synthesis in Saccharomyces cerevisiae., PMID:29804512
Multi-omics Reveal Specific Targets of the RNA-Binding Protein Puf3p and Its Orchestration of Mitochondrial Biogenesis., PMID:29248374
Multi-omic Mitoprotease Profiling Defines a Role for Oct1p in Coenzyme Q Production., PMID:29220658
A novel inborn error of the coenzyme Q10 biosynthesis pathway: cerebellar ataxia and static encephalomyopathy due to COQ5 C-methyltransferase deficiency., PMID:29044765
Disruption of the human COQ5-containing protein complex is associated with diminished coenzyme Q10 levels under two different conditions of mitochondrial energy deficiency., PMID:27155576
AarF Domain Containing Kinase 3 (ADCK3) Mutant Cells Display Signs of Oxidative Stress, Defects in Mitochondrial Homeostasis and Lysosomal Accumulation., PMID:26866375
The quantitative changes in the yeast Hsp70 and Hsp90 interactomes upon DNA damage., PMID:26217697
Biosynthesis of coenzyme Q in eukaryotes., PMID:26183239
Yeast Coq9 controls deamination of coenzyme Q intermediates that derive from para-aminobenzoic acid., PMID:26008578
Molecular characterization of the human COQ5 C-methyltransferase in coenzyme Q10 biosynthesis., PMID:25152161
Crystal structures and catalytic mechanism of the C-methyltransferase Coq5 provide insights into a key step of the yeast coenzyme Q synthesis pathway., PMID:25084328
Genome-wide linkage analysis and association study identifies loci for polydactyly in chickens., PMID:24752238
Coenzyme Q supplementation or over-expression of the yeast Coq8 putative kinase stabilizes multi-subunit Coq polypeptide complexes in yeast coq null mutants., PMID:24406904
Detection of suppressed maturation of the human COQ5 protein in the mitochondria following mitochondrial uncoupling by an antibody recognizing both precursor and mature forms of COQ5., PMID:23354120
Pericellular pH homeostasis is a primary function of the Warburg effect: inversion of metabolic systems to control lactate steady state in tumor cells., PMID:22320183
Involvement of a broccoli COQ5 methyltransferase in the production of volatile selenium compounds., PMID:19656903
Hydroxylation of demethoxy-Q6 constitutes a control point in yeast coenzyme Q6 biosynthesis., PMID:19002377
Yeast Coq5 C-methyltransferase is required for stability of other polypeptides involved in coenzyme Q biosynthesis., PMID:14701817
Caenorhabditis elegans ubiquinone biosynthesis genes., PMID:14695939
The yeast gene COQ5 is differentially regulated by Mig1p, Rtg3p and Hap2p., PMID:12393187
The regulation of COQ5 gene expression by energy source., PMID:12069115
Characterization of the COQ5 gene from Saccharomyces cerevisiae. Evidence for a C-methyltransferase in ubiquinone biosynthesis., PMID:9083049
The COQ5 gene encodes a yeast mitochondrial protein necessary for ubiquinone biosynthesis and the assembly of the respiratory chain., PMID:9083048
For research use only. Not for human or drug use.
