Catalog No.
YHC99001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg375-Asp583
Predicted molecular weight
25.86 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P13637
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ATP1A3, Na(+)/K(+) ATPase alpha-3 subunit, Sodium/potassium-transporting ATPase subunit alpha-3, Na(+)/K(+) ATPase alpha(III) subunit, Sodium pump subunit alpha-3
Integrated transcriptomics and metabolomics unravel the key metabolic pathways involved in the therapeutic mechanism of Salvianic acid A against hepatic fibrosis., PMID:40389097
An in silico analysis of dicofol-induced neurotoxicity mechanisms in humans., PMID:40169113
Subjective cognitive decline in conjunction with cerebrospinal fluid anti-ATP1A3 autoantibodies and a low amyloid β 1-42/1-40 ratio: Report and literature review., PMID:40101839
Mogrol Regulates the Expression of ATPase Na+/K+ Transport Subunit 3, Inhibits Cardiomyocyte Apoptosis, and Plays a Protective Role Against Myocardial Infarction., PMID:40051467
ATP1A3 Variants, Variably Penetrant Short QT Intervals, and Lethal Ventricular Arrhythmias., PMID:40029639
Bridging the gap: investigating the role of phosphorylation at the serine 129 site of α-synuclein in VAPB-PTPIP51 interactions., PMID:39994794
Critical Events in Patients With Alternating Hemiplegia of Childhood: A Cohort Study Subgroup Analysis., PMID:39945148
Progressive central cardiorespiratory rate downregulation and intensifying epilepsy lead to sudden unexpected death in epilepsy in mouse model of the most common human ATP1A3 mutation., PMID:39797721
Neurological and psychiatric characterization of rapid-onset dystonia-parkinsonism over time., PMID:39731885
ATP1A3-Associated Paroxysmal Dystonia., PMID:39712145
Novel mouse model of alternating hemiplegia of childhood exhibits prominent motor and seizure phenotypes., PMID:39603281
ATP1A3 dysfunction causes motor hyperexcitability and afterhyperpolarization loss in a dystonia model., PMID:39533828
Phosphorylated tau in cerebrospinal fluid-derived extracellular vesicles in Alzheimer's disease: a pilot study., PMID:39455624
A case of alternating hemiplegia in 2-month-old children with nystagmus as the first symptom: A case report., PMID:39331927
Epilepsy with eyelid myoclonia in a patient with ATP1A3-related neurologic disorder., PMID:39235869
In vitro study of ATP1A3 p.Ala275Pro mutant causing alternating hemiplegia of childhood and rapid-onset dystonia-parkinsonism., PMID:39145297
Phenotype Distinctions in Mice Deficient in the Neuron-Specific α3 Subunit of Na,K-ATPase: Atp1a3tm1Ling/+ and Atp1a3 +/D801Y., PMID:39111836
Sex-dependent changes in AMPAR expression and Na, K-ATPase activity in the cerebellum and hippocampus of α-Klotho-Hypomorphic mice., PMID:39094831
Navigating the Complexity of Alternating Hemiplegia in Childhood: A Comprehensive Review., PMID:39088707
Na,K-ATPase Expression Can Be Limited Post-Transcriptionally: A Test of the Role of the Beta Subunit, and a Review of Evidence., PMID:39000521
Alternating hemidystonia of childhood: a unique presentation of ATP1A3 treated with trihexyphenidyl., PMID:38839636
Childhood fever and hearing loss associated with CAPOS syndrome., PMID:38821025
ATP1A3 regulates protein synthesis for mitochondrial stability under heat stress., PMID:38804677
Neuronal autosis is Na+/K+-ATPase alpha 3-dependent and involved in hypoxic-ischemic neuronal death., PMID:38796484
ATP1A3 Disease Spectrum Includes Paroxysmal Weakness and Encephalopathy Not Triggered by Fever., PMID:38685976
Concerns about efficacy of deep brain stimulation (DBS) in centromedian-parafascicular thalamic complex for rapid onset dystonia-parkinsonism (DYT12-ATP1A3)., PMID:38685261
Adenylate kinase 4 promotes neuronal energy metabolism and mitophagy in early cerebral ischemia via Parkin/PKM2 pathway., PMID:38670251
Analysis of the sodium pump subunit ATP1A3 in glioma patients: Potential value in prognostic prediction and immunotherapy., PMID:38615384
Clinical and genetic architecture of a large cohort with auditory neuropathy., PMID:38456936
Dopa-responsive dystonia and paroxysmal dystonic attacks associated with ATP1A3 gene variant., PMID:38453474
[Clinical features of CAPOS syndrome caused by maternal ATP1A3 gene variation: a case report]., PMID:38297853
"Alternating" the Diagnosis after 40 Years of Disease: The Thousand Faces of ATP1A3 Mutation., PMID:38247386
Childhood-related neural genotype-phenotype in ATP1A3 mutations: comprehensive analysis., PMID:38243045
Exome sequencing of ATP1A3-negative cases of alternating hemiplegia of childhood reveals SCN2A as a novel causative gene., PMID:38097767
Characteristics of non-sleep related apneas in children with alternating hemiplegia of childhood., PMID:38096596
Alternating hemiplegia of childhood., PMID:38043964
The expanding genetic landscape of myoclonus-dystonia syndrome: YY1 and ATP1A3 are added to the list., PMID:37981540
ATP1A3 related disease manifesting as rapid onset dystonia-parkinsonism with prominent myoclonus and exaggerated startle., PMID:37827923
Cilostazol treats transient heart failure caused by ATP1A3 variant-associated polymicrogyria., PMID:37778966
ATP1A3 as a target for isolating neuron-specific extracellular vesicles from human brain and biofluids., PMID:37713494
Centromedian-parafascicular complex deep brain stimulation improves motor symptoms in rapid onset Dystonia-Parkinsonism (DYT12-ATP1A3)., PMID:37634624
Precision therapy for a medically actionable ATP1A3 variant from a genomic medicine program in an underserved population., PMID:37614148
Whole exome sequencing and clinical investigation of young onset dystonia: What can we learn?, PMID:37607452
Brain structural changes in alternating hemiplegia of childhood using single-case voxel-based morphometry analysis., PMID:37604479
Expanding the Allelic spectrum in ATP1A3-related disorders with 3 novel mutations and clinic features., PMID:37482377
Effect of Oxygen Administration on Paroxysmal Motor Events in Alternating Hemiplegia of Childhood., PMID:37466145
Identification of N1 methyladenosine-related biomarker predicting overall survival outcomes and experimental verification in ovarian cancer., PMID:37435915
Blood neurofilament light chain as a surrogate marker for dystonia., PMID:37422850
Epilepsy with eyelid myoclonia in the setting of de novo pathogenic variant in ATP1A3., PMID:37293976
For research use only. Not for human or drug use.
