Catalog No.
YHK94501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ser193
Predicted molecular weight
23.55 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q6NXG1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
RNA-binding protein 35A, Epithelial splicing regulatory protein 1, ESRP1, RNA-binding motif protein 35A, RBM35A
Systematic analysis of the effects of splicing on the diversity of post-translational modifications in protein isoforms using PTM-POSE., PMID:40513562
Delta-catenin is required for cell proliferation in virus-positive Merkel cell carcinoma cell lines but not in human fibroblasts., PMID:40407323
Esrp1 and Esrp2 regulate the stability of tmc1/2a mRNAs in zebrafish sensory hair cells., PMID:40086870
The role of ESRP1 in solid tumor development through the regulation of CD44 splicing and EMT processes., PMID:40046628
Full-length transcriptome atlas of gallbladder cancer reveals trastuzumab resistance conferred by ERBB2 alternative splicing., PMID:39948369
Splicing diversity enhances the molecular classification of pituitary neuroendocrine tumors., PMID:39934142
A distinct alternative mRNA splicing profile identifies the oncogenic CD44 transcript variant 3 in KMT2A-rearranged pediatric T-cell acute lymphoblastic leukemia cells., PMID:39793727
The splicing machinery is dysregulated and represents a therapeutic vulnerability in breast cancer., PMID:39725737
Epithelial splicing regulatory protein 1 promotes peritoneal dissemination of ovarian cancer by inducing the formation of circular RNAs modulating epithelial plasticity., PMID:39461579
Telomere transcripts act as tumor suppressor and are associated with favorable prognosis in colorectal cancer with low proliferating cell nuclear antigen expression., PMID:39222177
Functional analysis of ESRP1/2 gene variants and CTNND1 isoforms in orofacial cleft pathogenesis., PMID:39179789
Potential impact of epithelial splicing regulatory protein 1 (ESRP1) associated with tumor immunity in pancreatic adenocarcinoma., PMID:39127164
Molecular biological role of epithelial splicing regulatory protein 1 in intrahepatic cholangiocarcinoma., PMID:39037743
ESRP1-mediated biogenesis of circPTPN12 inhibits hepatocellular carcinoma progression by PDLIM2/ NF-κB pathway., PMID:38992675
ACLY alternative splicing correlates with cancer phenotypes., PMID:38815867
CircZFR promotes colorectal cancer progression via stabilizing BCLAF1 and regulating the miR-3127-5p/RTKN2 axis., PMID:38805063
Kinesin KIF3A regulates meiotic progression and spindle assembly in oocyte meiosis., PMID:38587639
Tropomyosin1 isoforms underlie epithelial to mesenchymal plasticity, metastatic dissemination, and resistance to chemotherapy in high-grade serous ovarian cancer., PMID:38365970
HTATIP2 Overexpression was Associated With a Good Prognosis in Gastric Cancer., PMID:38303513
Systematic analysis of the effects of splicing on the diversity of post-translational modifications in protein isoforms using PTM-POSE., PMID:38260432
Hyaluronan delays human amniotic epithelial stem cell senescence by regulating CD44 isoform switch to activate AKT/mTOR signals., PMID:38159379
ESRP1-driven alternative splicing of CLSTN1 inhibits the metastasis of gastric cancer., PMID:38114495
Role of epithelial splicing regulatory protein 1 in cancer progression., PMID:38110955
RNA-binding proteins regulating the CD44 alternative splicing., PMID:38106992
ESRP1 controls biogenesis and function of a large abundant multiexon circRNA., PMID:38015468
Splicing factor ESRP1 derived circ_0068162 promotes the progression of oral squamous cell carcinoma via the miR-186/JAG axis., PMID:37966490
The calcium channel TRPC6 promotes chemotherapy-induced persistence by regulating integrin α6 mRNA splicing., PMID:37910503
Epithelial specific splicing regulator proteins as emerging oncogenes in aggressive prostate cancer., PMID:37752235
Genes with dual proto-oncogene and tumor suppressor gene activities are frequently altered by protein losses in colon cancers., PMID:37429176
LncRNA CCAT2 promotes malignant progression of metastatic gastric cancer through regulating CD44 alternative splicing., PMID:37354353
Downregulated ESRP1/2 promotes lung metastasis of bladder carcinoma through altering FGFR2 splicing and macrophage polarization., PMID:37090731
Matrix stiffness regulates tumor cell intravasation through expression and ESRP1-mediated alternative splicing of MENA., PMID:37027295
Study on differentially expressed genes and participating pathways of ectopic endometrium in adenomyosis patients with different data sets., PMID:37019419
The Role of ESRP1 in the Regulation of PHGDH in Estrogen Receptor-Positive Breast Cancer., PMID:36925195
Characterization of alternative mRNA splicing in cultured cell populations representing progressive stages of human fetal kidney development., PMID:36380228
Alternative splicing downstream of EMT enhances phenotypic plasticity and malignant behavior in colon cancer., PMID:36346211
ESRP1-regulated isoform switching of LRRFIP2 determines metastasis of gastric cancer., PMID:36307405
The global Protein-RNA interaction map of ESRP1 defines a post-transcriptional program that is essential for epithelial cell function., PMID:36238894
Underlying mechanisms of epithelial splicing regulatory proteins in cancer progression., PMID:36163376
A Regulatory Axis between Epithelial Splicing Regulatory Proteins and Estrogen Receptor α Modulates the Alternative Transcriptome of Luminal Breast Cancer., PMID:35887187
Circular RNA circ-TNPO3 inhibits clear cell renal cell carcinoma metastasis by binding to IGF2BP2 and destabilizing SERPINH1 mRNA., PMID:35876041
Presence of spontaneous epithelial-mesenchymal plasticity in esophageal cancer., PMID:35330672
Silencing ESRP1 expression promotes caspase-independent cell death via nuclear translocation of AIF in colon cancer cells., PMID:34986387
RBPMS2, as a novel biomarker for predicting lymph node metastasis, guides therapeutic regimens in gastric cancer., PMID:34981466
Comprehensive Analysis of Alternative Splicing in Gastric Cancer Identifies Epithelial-Mesenchymal Transition Subtypes Associated with Survival., PMID:34903603
Circ_0092367 Inhibits EMT and Gemcitabine Resistance in Pancreatic Cancer via Regulating the miR-1206/ESRP1 Axis., PMID:34828307
CircESRP1 inhibits clear cell renal cell carcinoma progression through the CTCF-mediated positive feedback loop., PMID:34775467
Position Specific Alternative Splicing and Gene Expression Profiles Along the Tonotopic Axis of Chick Cochlea., PMID:34568429
Overexpression of Epithelial Splicing Regulatory Protein 1 in Metastatic Lesions of Serous Ovarian Carcinoma Correlates with Poor Patient Prognosis., PMID:34495766
MiR-337-3p suppresses migration and invasion of breast cancer cells by downregulating ESRP1., PMID:34481218
For research use only. Not for human or drug use.
