Catalog No.
YHG05601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Pro123
Predicted molecular weight
17.20 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q05682
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Caldesmon, CAD, CALD1, CDM
Identification of Selected Genes Associated With the Prediction of Prognosis in Bladder Cancer., PMID:40370233
CALD1 inhibits invasion of human ovarian cancer cells by affecting cytoskeletal structure and the number of focal adhesion., PMID:40104711
Identification of novel biomarkers associated with immune infiltration in major depression disorder and atopic dermatitis., PMID:39953304
Spatial transcriptomics analysis identifies therapeutic targets in diffuse high-grade gliomas., PMID:39530009
Endothelin-1 potentiated constriction in preeclampsia placental veins: Role of ETAR/ETBR/CaV1.2/CALD1., PMID:39476475
Genetically engineered CD276-anchoring biomimetic nanovesicles target senescent escaped tumor cells to overcome chemoresistant and immunosuppressive breast cancer., PMID:39226654
Insight in the (Phospho)proteome of Vascular Smooth Muscle Cells Derived From Patients With Abdominal Aortic Aneurysm Reveals Novel Disease Mechanisms., PMID:39206541
XTP8 Promotes Ovarian Cancer Progression by Activating AKT/AMPK/mTOR Pathway to Regulate EMT., PMID:38717641
CALD1 facilitates epithelial-mesenchymal transition progression in gastric cancer cells by modulating the PI3K-Akt pathway., PMID:38577446
Unraveling the mechanism in l-Caldesmon regulating the osteogenic differentiation of PDLSCs: An innovative perspective., PMID:38513808
The gene expression of CALD1, CDH2, and POSTN in fibroblast are related to idiopathic pulmonary fibrosis., PMID:38370408
Upregulation of CALD1 predicted a poor prognosis for platinum-treated ovarian cancer and revealed it as a potential therapeutic resistance target., PMID:38365611
Explore Key Genes and Mechanisms Involved in Colon Cancer Progression Based on Bioinformatics Analysis., PMID:38294732
Hub biomarkers in ultrasound-guided bladder cancer and osteosarcoma: Myosin light chain kinase and caldesmon., PMID:38050320
MiR-1278 targets CALD1 and suppresses the progression of gastric cancer via the MAPK pathway., PMID:38025524
MYLK and CALD1 as molecular targets in bladder cancer., PMID:38013282
Identification of RECK as a protective prognostic indicator and a tumor suppressor through regulation of the ERK/MAPK signaling pathway in gastric cancer., PMID:37904179
Functional mutation, splice, distribution, and divergence analysis of impactful genes associated with heart failure and other cardiovascular diseases., PMID:37798313
Predictive value of serum proteomic biomarkers for noise-induced hearing loss., PMID:37582891
Glucocorticoid receptor-induced non-muscle caldesmon regulates metastasis in castration-resistant prostate cancer., PMID:37573448
TGM2, HMGA2, FXYD3, and LGALS4 genes as biomarkers in acquired oxaliplatin resistance of human colorectal cancer: A systems biology approach., PMID:37535601
Alterations of the m6A Methylation Induced by TGF-β2 in ARPE-19 Cells., PMID:37525909
Identification of the hub genes associated with prostate cancer tumorigenesis., PMID:37251946
Dual thick and thin filament linked regulation of stretch- and L-NAME-induced tone in young and senescent murine basilar artery., PMID:37057180
METTL14 Promotes Oral Squamous Cell Carcinoma Progression by Regulating the mRNA and m6A Levels of CALD1., PMID:37017680
Predicting Key Genes and Therapeutic Molecular Modelling to Explain the Association between Porphyromonas gingivalis (P. gingivalis) and Alzheimer's Disease (AD)., PMID:36982508
Prognostic Value of EMT Gene Signature in Malignant Mesothelioma., PMID:36901697
Quantitative proteomic analysis of human serum using tandem mass tags to predict cardiovascular risks in patients with psoriasis., PMID:36804462
Immunohistochemical Expression Analysis of Caldesmon Isoforms in Colorectal Carcinoma Reveals Interesting Correlations with Tumor Characteristics., PMID:36768598
Identification of tumor antigens and immune landscapes for bladder urothelial carcinoma mRNA vaccine., PMID:36761744
Single-cell RNA sequencing reveals changes in glioma-associated macrophage polarization and cellular states of malignant gliomas with high AQP4 expression., PMID:36599974
Shared genetic architecture of hernias: A genome-wide association study with multivariable meta-analysis of multiple hernia phenotypes., PMID:36584111
Identification of Hub Genes Associated with Progression and Prognosis of Bladder Cancer by Integrated Bioinformatics Analysis., PMID:36472061
AHSA1 Promotes Proliferation and EMT by Regulating ERK/CALD1 Axis in Hepatocellular Carcinoma., PMID:36230524
Emerging role of caldesmon in cancer: A potential biomarker for colorectal cancer and other cancers., PMID:36187394
Exploration of new therapeutic targets for viral hepatic fibrosis, alcoholic hepatic fibrosis, and non-alcoholic hepatic fibrosis., PMID:36111046
Discovering Gene Signature Shared by Prostate Cancer and Neurodegenerative Diseases Based on the Bioinformatics Approach., PMID:35799671
MIR100HG Regulates CALD1 Gene Expression by Targeting miR-142-5p to Affect the Progression of Bladder Cancer Cells in vitro, as Revealed by Transcriptome Sequencing., PMID:35127818
Identification of key genes associated with esophageal adenocarcinoma based on bioinformatics analysis., PMID:35071405
[Bioinformatics-based identification of the key genes associated with prostate cancer]., PMID:34914287
Cancer-associated stroma reveals prognostic biomarkers and novel insights into the tumour microenvironment of colorectal cancer and colorectal liver metastases., PMID:34874125
Identification of crucial genes involved in pathogenesis of regional weakening of the aortic wall., PMID:34852854
CALD1 promotes the expression of PD-L1 in bladder cancer via the JAK/STAT signaling pathway., PMID:34733993
Quantitative Expression of TYR, CD34, and CALD1 Discriminates Between Canine Oral Malignant Melanomas and Soft Tissue Sarcomas., PMID:34422947
Spatial transcriptomics analysis of uterine gene expression in enhancer of zeste homolog 2 conditional knockout mice†., PMID:34344022
Morphologically malignant nodular fasciitis with CALD1-USP6 fusion., PMID:34213575
Copy number alteration profiling facilitates differential diagnosis between ossifying fibroma and fibrous dysplasia of the jaws., PMID:34188021
Caldesmon ablation in mice causes umbilical herniation and alters contractility of fetal urinary bladder smooth muscle., PMID:34115104
Laryngeal squamous cell carcinoma cell lines show high tolerance for siRNA-mediated CDK1 knockdown., PMID:34094670
Weighted Gene Co-expression Network Analysis Identifies CALD1 as a Biomarker Related to M2 Macrophages Infiltration in Stage III and IV Mismatch Repair-Proficient Colorectal Carcinoma., PMID:33996905