Catalog No.
YHF38901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-His142
Predicted molecular weight
18.88 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P60983
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Glia maturation factor beta, GMFB, GMF-beta
Extracellular GMFB activates the non-canonical FAS-FAF1 pathway to induce lysosomal dysfunction in early diabetic retinopathy., PMID:40490177
Glial maturation factor-β deficiency prevents oestrogen deficiency-induced bone loss by remodelling the actin network to suppress adipogenesis of bone marrow mesenchymal stem cells., PMID:39543090
SUMOylation of GMFB regulates its stability and function in retinal pigment epithelial cells under hyperglycemia., PMID:38657921
GMFB/AKT/TGF-β3 in Müller cells mediated early retinal degeneration in a streptozotocin-induced rat diabetes model., PMID:37904673
G9a Inhibition Promotes Neuroprotection through GMFB Regulation in Alzheimer's Disease., PMID:37307824
Glia maturation factor beta deficiency protects against diabetic osteoporosis by suppressing osteoclast hyperactivity., PMID:37121966
Highly-expressed circ_0129657 inhibits proliferation as well as promotes apoptosis and inflammation in HBMECs after oxygen-glucose deprivation via miR-194-5p/GMFB axis., PMID:37073559
Expression of GMFB in High-Grade Cervical Intraepithelial Neoplasia and Its Role in Cervical Cancer., PMID:36238479
Candidate biomarkers in brown adipose tissue for post-mortem diagnosis of fatal hypothermia., PMID:36175800
Glia Maturation Factor-β Supports Liver Regeneration by Remodeling Actin Network to Enhance STAT3 Proliferative Signals., PMID:35953024
Glia maturation factor-β induces ferroptosis by impairing chaperone-mediated autophagic degradation of ACSL4 in early diabetic retinopathy., PMID:35325805
Glia Maturation Factor Beta as a Novel Biomarker and Therapeutic Target for Hepatocellular Carcinoma., PMID:34796110
MicroRNA-5195-3p alleviates high glucose‑induced injury in human ARPE-19 cells by targeting GMFB., PMID:34793551
A proteomic view on the differential phenotype of Schwann cells derived from mouse sensory and motor nerves., PMID:32857427
Analysis of the Clinical Diagnostic Value of GMFB in Cerebral Infarction., PMID:32039676
Brain-Derived Glia Maturation Factor β Participates in Lung Injury Induced by Acute Cerebral Ischemia by Increasing ROS in Endothelial Cells., PMID:30191459
Glia maturation factor beta is required for reactive gliosis after traumatic brain injury in zebrafish., PMID:29655639
Quantitative Proteomic Analysis of the Hippocampus of Rats with GCR-Induced Spatial Memory Impairment., PMID:29206597
Actin network disassembly powers dissemination of Listeria monocytogenes., PMID:24155331
The expression of glia maturation factors and the effect of glia maturation factor-γ on angiogenic sprouting in zebrafish., PMID:23333559
Identification of glia maturation factor beta as an independent prognostic predictor for serous ovarian cancer., PMID:20547056
Heterozygous deletion at 14q22.1-q22.3 including the BMP4 gene in a patient with psychomotor retardation, congenital corneal opacity and feet polysyndactyly., PMID:18925664
Proteome analysis of human substantia nigra in Parkinson's disease., PMID:18275612
Glia maturation factor-beta is produced by thymoma and may promote intratumoral T-cell differentiation., PMID:16115230
Expression of glia maturation factor beta after cryogenic brain injury., PMID:15661366
Sensitive immunoassays for human and rat GMFB and GMFG, tissue distribution and age-related changes., PMID:14980447
[Functional angiogenesis induction in epigastric islet flap rat model after genetic modification of fibroblasts]., PMID:14518341
Structure and promoter activity of the human glia maturation factor-gamma gene: a TATA-less, GC-rich and bidirectional promoter., PMID:12591611
Platelet-derived growth factor-AA-mediated functional angiogenesis in the rat epigastric island flap after genetic modification of fibroblasts is ischemia dependent., PMID:11935129
Expression of glia maturation factor during retinal development in the rat., PMID:11687281
Identification and isolation of a full-length clone of mouse GMFB (Gmfb), a putative intracellular kinase regulator, differentially expressed in telencephalon., PMID:11435704
[Review of the research of glia maturation factor and cloning of human and rat glia maturation factor-gamma (GMFG) cDNA]., PMID:11400321
Cloning of a rat glia maturation factor-gamma (rGMFG) cDNA and expression of its mRNA and protein in rat organs., PMID:10731725
Genetically modified fibroblasts induce angiogenesis in the rat epigastric island flap., PMID:9860229
Immunoglobulin heavy-chain allotypes play a role in the clinical history of celiac disease., PMID:1789993
Gm allotyping to determine the origin of red cell antibodies in recipients of solid organ transplants., PMID:3604171
Gm allotyping to determine the origin of the anti-D causing hemolytic anemia in a kidney transplant recipient., PMID:3111092
Genetic factors in Graves' ophthalmopathy., PMID:3113776
Quantification of IgG subclasses in sera of normal adults and healthy children between 4 and 12 years of age., PMID:54236
For research use only. Not for human or drug use.
