Catalog No.
YHA66001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly121-Ser242
Predicted molecular weight
15.64 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O43390
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Heterogeneous nuclear ribonucleoprotein R, hnRNP R, HNRNPR, HNRPR
METTL3-dependent m6A modification of GHR mRNA regulates mitochondrial function through mitochondrial biogenesis during myoblast differentiation., PMID:40344709
HnRNPR promotes non-small cell lung cancer progression by protecting XB130 mRNA from XRN1- and DIS3L2-mediated degradation., PMID:40268079
An evolutionarily conserved tryptophan cage promotes folding of the extended RNA recognition motif in the hnRNPR-like protein family., PMID:40247750
hnRNP R promotes O-GlcNAcylation of eIF4G and facilitates axonal protein synthesis., PMID:39198412
Integrative Proteomics-Metabolomics of In Vitro Degeneration of Cardiovascular Cell Lines., PMID:39110328
A model-free and distribution-free multi-omics integration approach for detecting novel lung adenocarcinoma genes., PMID:39097651
Sporadic Amyotrophic Lateral Sclerosis Skeletal Muscle Transcriptome Analysis: A Comprehensive Examination of Differentially Expressed Genes., PMID:38540795
HnRNPR-mediated UPF3B mRNA splicing drives hepatocellular carcinoma metastasis., PMID:38402949
HNRNPA2B1 and HNRNPR stabilize ASCL1 in an m6A-dependent manner to promote neuroblastoma progression., PMID:38331110
JUN-induced super-enhancer RNA forms R-loop to promote nasopharyngeal carcinoma metastasis., PMID:37479693
Cytosolic Ptbp2 modulates axon growth in motoneurons through axonal localization and translation of Hnrnpr., PMID:37438340
HnRNPR strongly represses splicing of a critical exon associated with spinal muscular atrophy through binding to an exonic AU-rich element., PMID:37225410
Pan-cancer analysis of the oncogenic role of HNRNPR in human tumors., PMID:37077028
Therapeutic reduction of GGGGCC repeat RNA levels by hnRNPA3 suppresses neurodegeneration in Drosophila models of C9orf72-linked ALS/FTD., PMID:36611007
Single-Cell Transcriptome Analysis Reveals Paraspeckles Expression in Osteosarcoma Tissues., PMID:36507075
High expression of HNRNPR in ESCA combined with 18F-FDG PET/CT metabolic parameters are novel biomarkers for preoperative diagnosis of ESCA., PMID:36195940
The hnRNPK/A1/R/U Complex Regulates Gene Transcription and Translation and is a Favorable Prognostic Biomarker for Human Colorectal Adenocarcinoma., PMID:35875075
hnRNP R negatively regulates transcription by modulating the association of P-TEFb with 7SK and BRD4., PMID:35856391
Loss of full-length hnRNP R isoform impairs DNA damage response in motoneurons by inhibiting Yb1 recruitment to chromatin., PMID:34850154
RNA-binding protein hnRNPR reduces neuronal cholesterol levels by binding to and suppressing HMGCR., PMID:34258925
Rare deleterious mutations of HNRNP genes result in shared neurodevelopmental disorders., PMID:33874999
HnRNPR-CCNB1/CENPF axis contributes to gastric cancer proliferation and metastasis., PMID:31527303
BDNF elevates the axonal levels of hnRNPs Q and R in cultured rat cortical neurons., PMID:31202892
HNRNPR Variants that Impair Homeobox Gene Expression Drive Developmental Disorders in Humans., PMID:31079900
Heterogeneous nuclear ribonucleoproteins R and Q accumulate in pathological inclusions in FTLD-FUS., PMID:30755280
CCAR-1 affects hemidesmosome biogenesis by regulating unc-52/perlecan alternative splicing in the C. elegans epidermis., PMID:29748380
Identification of Key Candidate Proteins and Pathways Associated with Temozolomide Resistance in Glioblastoma Based on Subcellular Proteomics and Bioinformatical Analysis., PMID:29687002
HNRNPR Regulates the Expression of Classical and Nonclassical MHC Class I Proteins., PMID:27194785
Identification of allelic expression imbalance genes in human hepatocellular carcinoma through massively parallel DNA and RNA sequencing., PMID:27000824
Epigenetic modifications of splicing factor genes in myelodysplastic syndromes and acute myeloid leukemia., PMID:25220401
Shutdown of achaete-scute homolog-1 expression by heterogeneous nuclear ribonucleoprotein (hnRNP)-A2/B1 in hypoxia., PMID:25124043
Interaction of survival of motor neuron (SMN) and HuD proteins with mRNA cpg15 rescues motor neuron axonal deficits., PMID:21652774
Versatility of MicroRNA biogenesis., PMID:21572999
Landscape of the SOX2 protein-protein interactome., PMID:21280222
Regulation of post-translational protein arginine methylation during HeLa cell cycle., PMID:20541591
The heterogeneous nuclear ribonucleoprotein-R is necessary for axonal beta-actin mRNA translocation in spinal motor neurons., PMID:20167579
Changed profile of splicing regulator genes expression in response to exercise., PMID:19902070
Identification of a heterogeneous nuclear ribonucleoprotein-recognition region in the HIV Rev protein., PMID:19808671
HRP-2, the Caenorhabditis elegans homolog of mammalian heterogeneous nuclear ribonucleoproteins Q and R, is an alternative splicing factor that binds to UCUAUC splicing regulatory elements., PMID:19706616
Heterogeneous nuclear ribonucleoprotein R enhances transcription from the naturally configured c-fos promoter in vitro., PMID:19581295
The expression pattern of heterogeneous nuclear ribonucleoprotein R in rat retina., PMID:19015982
hnRNP-R regulates the PMA-induced c-fos expression in retinal cells., PMID:18197392
ASPIC: a web resource for alternative splicing prediction and transcript isoforms characterization., PMID:16845044
Cloning and expression of a novel isoform of heterogeneous nuclear ribonucleoprotein-R., PMID:15858414
Autoantibodies to heterogeneous nuclear ribonucleoproteins., PMID:15804702
Axonal defects in mouse models of motoneuron disease., PMID:14704958
Specific interaction of Smn, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: a role for Smn in RNA processing in motor axons?, PMID:11773003
Two-hybrid cloning identifies an RNA-binding protein, GRY-RBP, as a component of apobec-1 editosome., PMID:11352648
Identification of STKA-dependent genes in Dictyostelium discoideum., PMID:11100898
A novel heterogeneous nuclear ribonucleoprotein-like protein interacts with NS1 of the minute virus of mice., PMID:9847309
For research use only. Not for human or drug use.
