Catalog No.
YHK93001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser115-Lys175
Predicted molecular weight
19.58 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9P032
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4, Hormone-regulated proliferation-associated protein of 20 kDa, NDUFAF4, HRPAP20, C6orf66
Scent of COVID-19: Whole-Genome Sequencing Analysis Reveals the Role of ACE2, IFI44, and NDUFAF4 in Long-Lasting Olfactory Dysfunction., PMID:39859996
Identification of mitophagy-related genes and analysis of immune infiltration in the astrocytes based on machine learning in the pathogenesis of major depressive disorder., PMID:39284527
Unravelling the role of NDUFAF4 in Colon Cancer: Insights from multi-omics analysis., PMID:39244022
Multiomics analysis identifies oxidative phosphorylation as a cancer vulnerability arising from myristoylation inhibition., PMID:38715059
A genetic variant in gene NDUFAF4 confers the risk of non-small cell lung cancer by perturbing hsa-miR-215 binding., PMID:37787384
The host cellular protein Ndufaf4 interacts with the vesicular stomatitis virus M protein and affects viral propagation., PMID:33635491
Complex I deficiency, due to NDUFAF4 mutations, causes severe mitochondrial dysfunction and is associated to early death and dysmorphia., PMID:32949790
Induction of the mitochondrial NDUFA4L2 protein by HIF-1a regulates heart regeneration by promoting the survival of cardiac stem cell., PMID:29953852
NDUFAF4 variants are associated with Leigh syndrome and cause a specific mitochondrial complex I assembly defect., PMID:28853723
Defective Expression of the Mitochondrial-tRNA Modifying Enzyme GTPBP3 Triggers AMPK-Mediated Adaptive Responses Involving Complex I Assembly Factors, Uncoupling Protein 2, and the Mitochondrial Pyruvate Carrier., PMID:26642043
Replacement of the C6ORF66 assembly factor (NDUFAF4) restores complex I activity in patient cells., PMID:23670274
Early complex I assembly defects result in rapid turnover of the ND1 subunit., PMID:22653752
Defective mitochondrial translation differently affects the live cell dynamics of complex I subunits., PMID:21978538
Mutations in NDUFAF3 (C3ORF60), encoding an NDUFAF4 (C6ORF66)-interacting complex I assembly protein, cause fatal neonatal mitochondrial disease., PMID:19463981
C6ORF66 is an assembly factor of mitochondrial complex I., PMID:18179882
Oligonucleotide microarray analysis of estrogen receptor alpha-positive postmenopausal breast carcinomas: identification of HRPAP20 and TIMELESS as outstanding candidate markers to predict the response to tamoxifen., PMID:17909269
HRPAP20: a novel calmodulin-binding protein that increases breast cancer cell invasion., PMID:17001319
For research use only. Not for human or drug use.
