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Recombinant Human CEP131 Protein, N-His

Catalog #:   YHK92901 Specific References (48) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: Q9UPN4
Protein length: Arg750-Ala1020
Overview

Catalog No.

YHK92901

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Arg750-Ala1020

Predicted molecular weight

34.68 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

Q9UPN4

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

AZI1, Pre-acrosome localization protein 1, Centrosomal protein of 131 kDa, KIAA1118, CEP131, 5-azacytidine-induced protein 1

Data Image
  • SDS-PAGE
    SDS PAGE for Recombinant Human CEP131 protein
References

CEP162: A critical regulator of ciliary transition zone assembly and its implications in ciliopathies., PMID:40270641

A polarized multicomponent foundation upholds ciliary central microtubules., PMID:39165107

Novel CDKL5 targets identified in human iPSC-derived neurons., PMID:39136782

The Unkempt RNA binding protein reveals a local translation program in centriole overduplication., PMID:39131325

Cep131-Cep162 and Cby-Fam92 complexes cooperatively maintain Cep290 at the basal body and contribute to ciliogenesis initiation., PMID:38442096

The centrosomal protein 131 participates in the regulation of mitochondrial apoptosis., PMID:38102401

O-GlcNAcylation Regulates Centrosome Behavior and Cell Polarity to Reduce Pulmonary Fibrosis and Maintain the Epithelial Phenotype., PMID:37963851

Loss of ATG4B and ATG4A results in two-stage cell cycle defects in pancreatic ductal adenocarcinoma cells., PMID:37701987

Study on the pathogenesis of MiR-6324 regulating diarrheal irritable bowel syndrome and bioinformatics analysis., PMID:36873998

Hepatic ARID3A facilitates liver cancer malignancy by cooperating with CEP131 to regulate an embryonic stem cell-like gene signature., PMID:36008383

Trisomy 21 increases microtubules and disrupts centriolar satellite localization., PMID:35476505

The SON RNA splicing factor is required for intracellular trafficking structures that promote centriole assembly and ciliogenesis., PMID:34406792

Proteomic Signature of Host Response to SARS-CoV-2 Infection in the Nasopharynx., PMID:34400346

USP9X Is Required to Maintain Cell Survival in Response to High-LET Radiation., PMID:34277417

The long non-coding RNA MEG3 plays critical roles in the pathogenesis of cholesterol gallstone., PMID:33665015

Fibrogranular materials function as organizers to ensure the fidelity of multiciliary assembly., PMID:33627667

CEP131 Abrogates CHK1 Inhibitor-Induced Replication Defects and Is Associated with Unfavorable Outcome in Neuroblastoma., PMID:33014050

CEP131 knockdown inhibits cell proliferation by inhibiting the ERK and AKT signaling pathways in non-small cell lung cancer., PMID:32218865

SNX17 Recruits USP9X to Antagonize MIB1-Mediated Ubiquitination and Degradation of PCM1 during Serum-Starvation-Induced Ciliogenesis., PMID:31671755

Zika virus increases mind bomb 1 levels, causing degradation of pericentriolar material 1 (PCM1) and dispersion of PCM1-containing granules from the centrosome., PMID:31666336

Cep131 overexpression promotes centrosome amplification and colon cancer progression by regulating Plk4 stability., PMID:31358734

Enhanced anticancer effects of a methylation inhibitor by inhibiting a novel DNMT1 target, CEP 131, in cervical cancer., PMID:31068247

Polo-like kinase 4 maintains centriolar satellite integrity by phosphorylation of centrosomal protein 131 (CEP131)., PMID:30804208

Atoh1 Controls Primary Cilia Formation to Allow for SHH-Triggered Granule Neuron Progenitor Proliferation., PMID:30695697

RNA-mediated gene fusion in mammalian cells., PMID:30538195

Human nuclear RNAi-defective 2 (NRDE2) is an essential RNA splicing factor., PMID:30538148

Coding mutations in NUS1 contribute to Parkinson's disease., PMID:30348779

Phosphoproteomic screening identifies physiological substrates of the CDKL5 kinase., PMID:30266825

Osmotic Stress Blocks Mobility and Dynamic Regulation of Centriolar Satellites., PMID:29932434

Structural centrosome aberrations sensitize polarized epithelia to basal cell extrusion., PMID:29899122

Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation., PMID:28878392

CEP131 indicates poor prognosis and promotes cell proliferation and migration in hepatocellular carcinoma., PMID:28694105

USP9X regulates centrosome duplication and promotes breast carcinogenesis., PMID:28361952

p38- and MK2-dependent signalling promotes stress-induced centriolar satellite remodelling via 14-3-3-dependent sequestration of CEP131/AZI1., PMID:26616734

Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication., PMID:26297806

Mapping of a blood pressure QTL on chromosome 17 in American Indians of the strong heart family study., PMID:25387527

The centriolar satellite protein AZI1 interacts with BBS4 and regulates ciliary trafficking of the BBSome., PMID:24550735

Acute versus chronic loss of mammalian Azi1/Cep131 results in distinct ciliary phenotypes., PMID:24415959

The AmAZI1ng roles of centriolar satellites during development., PMID:24385938

Cilia born out of shock and stress., PMID:24185901

A new cellular stress response that triggers centriolar satellite reorganization and ciliogenesis., PMID:24121310

Regulation of CEP131 gene expression by SP1., PMID:23137637

The centriolar satellite protein Cep131 is important for genome stability., PMID:22797915

Expression and distribution of genes encoding for polyamine-metabolizing enzymes in the different zones of male and female mouse kidneys., PMID:22562773

Dilatory is a Drosophila protein related to AZI1 (CEP131) that is located at the ciliary base and required for cilium formation., PMID:21750193

Cep70 and Cep131 contribute to ciliogenesis in zebrafish embryos., PMID:19254375

Genomic organization of the mouse AZ1 gene that encodes the protein localized to preacrosomes of spermatids., PMID:9070930

Isolation of a novel cDNA that encodes a protein localized to the pre-acrosome region of spermatids., PMID:8529672

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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Recombinant Human CEP131 Protein, N-His [YHK92901]
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