Catalog No.
YHK92701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
His2-Glu86
Predicted molecular weight
21.01 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8WWG9
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Minimum potassium ion channel-related peptide 3, Potassium voltage-gated channel subfamily E member 4, KCNE4, Potassium channel subunit beta MiRP3, MinK-related peptide 3
A missense mutation in the KCNE4 gene is not predictive of equine anhidrosis., PMID:39953936
The Expression, Purification, Spectroscopic Characterization, and Membrane Topology Classification of KCNE4 from Recombinant E. coli., PMID:39780724
Molecular mapping of KCNE4-dependent regulation of Kv1.3., PMID:39466181
KCNE4 is a crucial host factor for Orf virus infection by mediating viral entry., PMID:39118175
Crucial role for sensory nerves and Na/H exchanger inhibition in dapagliflozin- and empagliflozin-induced arterial relaxation., PMID:39056245
Prognostic value and potential regulatory relationship of miR-200c-5p in colorectal cancer., PMID:39016041
KCNE4-dependent modulation of Kv1.3 pharmacology., PMID:38880360
Vitamin D Receptor Deficiency Upregulates Pulmonary Artery Kv7 Channel Activity., PMID:37569725
Potassium voltage‑gated channel subfamily E member 4 facilitates the malignant progression of colon cancer by enhancing EGF containing fibulin extracellular matrix protein 2 expression., PMID:37456174
The Phosphorylation of Kv1.3: A Modulatory Mechanism for a Multifunctional Ion Channel., PMID:37345053
The novel KV7 channel activator URO-K10 exerts enhanced pulmonary vascular effects independent of the KCNE4 regulatory subunit., PMID:37295249
KCNE4 expression is correlated with the pathological characteristics of colorectal cancer patients and associated with the radioresistance of cancer cells., PMID:36459833
[Association study between the KCNE family gene polymorphisms of potassium channel gene and the susceptibility of atrial fibrillation]., PMID:36229204
Marked oestrous cycle-dependent regulation of rat arterial KV 7.4 channels driven by GPER1., PMID:36085551
Induction of potassium channel regulator KCNE4 in a submandibular lymph node metastasis model., PMID:35915077
Heterogeneous repolarization creates ventricular tachycardia circuits in healed myocardial infarction scar., PMID:35149693
AEBP1 Is One of the Epithelial-Mesenchymal Transition Regulatory Genes in Colon Adenocarcinoma., PMID:34938806
Integrated molecular analysis identifies a conserved pericyte gene signature in zebrafish., PMID:34751773
KCNE4-dependent functional consequences of Kv1.3-related leukocyte physiology., PMID:34272451
Calmodulin-dependent KCNE4 dimerization controls membrane targeting., PMID:34234241
Genomic Association of Chronic Idiopathic Anhidrosis to a Potassium Channel Subunit in a Large Animal Model., PMID:34081968
Molecular expression and functional features of Kv7 channels in human prostate smooth muscle., PMID:33420748
Reduced Graphene Oxides Modulate the Expression of Cell Receptors and Voltage-Dependent Ion Channel Genes of Glioblastoma Multiforme., PMID:33419226
Development of an Immune Infiltration-Related Eight-Gene Prognostic Signature in Colorectal Cancer Microenvironment., PMID:32908876
Uncovered Contribution of Kv7 Channels to Pulmonary Vascular Tone in Pulmonary Arterial Hypertension., PMID:32829658
Functional Consequences of the Variable Stoichiometry of the Kv1.3-KCNE4 Complex., PMID:32370164
Characterization and functional roles of KCNQ-encoded voltage-gated potassium (Kv7) channels in human corpus cavernosum smooth muscle., PMID:31919767
Triple-Colocalization Approach to Assess Traffic Patterns and Their Modulation., PMID:31432482
Targeting cholecystokinin-2 receptor for pancreatic cancer chemoprevention., PMID:31313401
The calmodulin-binding tetraleucine motif of KCNE4 is responsible for association with Kv1.3., PMID:30969795
Kcne4 deletion sex dependently inhibits the RISK pathway response and exacerbates hepatic ischemia-reperfusion injury in mice., PMID:30758982
[mRNA genomics change and significance of important ion channel proteins in patients with atrial fibrillation]., PMID:30392277
Kcne4 deletion sex-specifically predisposes to cardiac arrhythmia via testosterone-dependent impairment of RISK/SAFE pathway induction in aged mice., PMID:29844497
[Association of KCNE1 and KCNE4 gene polymorphisms with atrial fibrillation among Uygur and Han Chinese populations in Xinjiang]., PMID:28981946
β Subunits Control the Effects of Human Kv4.3 Potassium Channel Phosphorylation., PMID:28919864
Regulation of human cardiac potassium channels by full-length KCNE3 and KCNE4., PMID:27922120
The C-terminal domain of Kv1.3 regulates functional interactions with the KCNE4 subunit., PMID:27802162
Ion channels expression and function are strongly modified in solid tumors and vascular malformations., PMID:27716384
Kcne4 Deletion Sex-Dependently Alters Vascular Reactivity., PMID:27710966
KCNE4 and KCNE5: K(+) channel regulation and cardiac arrhythmogenesis., PMID:27484720
Novel exon 1 protein-coding regions N-terminally extend human KCNE3 and KCNE4., PMID:27162025
Fundamental role for the KCNE4 ancillary subunit in Kv7.4 regulation of arterial tone., PMID:26503181
Kcne4 deletion sex- and age-specifically impairs cardiac repolarization in mice., PMID:26399785
Auxiliary KCNE subunits modulate both homotetrameric Kv2.1 and heterotetrameric Kv2.1/Kv6.4 channels., PMID:26242757
The JNK1/JNK3 interactome--contributions by the JNK3 unique N-terminus and JNK common docking site residues., PMID:25301550
KCNQ and KCNE potassium channel subunit expression in bovine retinal pigment epithelium., PMID:24416770
[Association of single nucleotide polymorphism of KCNE1 and KCNE4 gene with atrial fibrillation in Xinjiang Uygur and Han population]., PMID:24370217
[Effect of additional disease (comorbidity) on association of allergic rhinitis with KCNE4 gene rs12621643 variant]., PMID:23866632
Molecular determinants of co- and post-translational N-glycosylation of type I transmembrane peptides., PMID:23718681
Intracellular trafficking of the KV1.3 potassium channel is regulated by the prodomain of a matrix metalloprotease., PMID:23300077
For research use only. Not for human or drug use.
