Catalog No.
YHK92301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala245-Leu380
Predicted molecular weight
17.58 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q70SY1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CREB3L2, Cyclic AMP-responsive element-binding protein 3-like protein 2, cAMP-responsive element-binding protein 3-like protein 2, BBF2H7, BBF2 human homolog on chromosome 7
Aberrant phase separation drives membranous organelle remodeling and tumorigenesis., PMID:40273917
Modulation of CREB3L2-ATF4 heterodimerization via proteasome inhibition and HRI activation in Alzheimer's disease pathology., PMID:40164587
Noncanonical UPR factor CREB3L2 drives immune evasion of triple-negative breast cancer through Hedgehog pathway modulation in T cells., PMID:39792663
Gene module reconstruction identifies cellular differentiation processes and the regulatory logic of specialized secretion in zebrafish., PMID:39591963
Post-stroke hippocampal neurogenesis is impaired by microvascular dysfunction and PI3K signaling in cerebral amyloid angiopathy., PMID:39392753
Endoplasmic reticulum exit sites are segregated for secretion based on cargo size., PMID:38991587
Single-cell transcriptome analysis reveals characteristic transcription factors in polydactyly., PMID:38708480
Molecular characterization of transcription factor CREB3L2 and CREB3L3 and their role in melanogenesis in Pacific oysters (Crassostrea gigas)., PMID:38604561
miR-92a-3p regulates ethanol-induced apoptosis in H9c2 cardiomyocytes., PMID:38582327
Novel KMT2B gene mutation in MUC4 positive low-grade fibromyxoid sarcoma., PMID:38347522
Comprehensive next-generation sequencing reveals low-grade fibromyxoid sarcoma of the vulva missed by morphological diagnosis: a case report., PMID:38293297
Gene module reconstruction elucidates cellular differentiation processes and the regulatory logic of specialized secretion., PMID:38234833
Independent activation of CREB3L2 by glucose fills a regulatory gap in mouse β-cells by co-ordinating insulin biosynthesis with secretory granule formation., PMID:38013154
Low-grade Fibromyxoid Sarcoma With Massive Degeneration: A Case of Unusual Gross and Histological Features., PMID:37905642
Regulatory mechanisms of the cAMP-responsive element binding protein 3 (CREB3) family in cancers., PMID:37595431
CREB3L2 Regulates Hemidesmosome Formation during Epithelial Sealing., PMID:37555472
Low-grade fibromyxoid sarcoma of the breast: genetic characterization and immunohistochemical comparison to morphologic mimics., PMID:37392946
Indicators of increased ER stress and UPR in aged D2-mdx and human dystrophic skeletal muscles., PMID:37179835
CREB3L2-ATF4 heterodimerization defines a transcriptional hub of Alzheimer's disease gene expression linked to neuropathology., PMID:36867706
A pilot study on identifying gene signatures as markers for predicting patient response to antiseizure medications., PMID:36658410
Integrating RNA-seq and scRNA-seq to explore the biological significance of NAD + metabolism-related genes in the initial diagnosis and relapse of childhood B-cell acute lymphoblastic leukemia., PMID:36439178
CREB3L1 and CREB3L2 control Golgi remodelling during decidualization of endometrial stromal cells., PMID:36313580
A systemic cell stress signal confers neuronal resilience toward oxidative stress in a Hedgehog-dependent manner., PMID:36260999
Expression analysis and functional characterization of thioredoxin domain-containing protein 11., PMID:36152228
Identification of transcription factors and construction of a novel miRNA regulatory network in primary osteoarthritis by integrated analysis., PMID:34856957
Single-cell analysis reveals androgen receptor regulates the ER-to-Golgi trafficking pathway with CREB3L2 to drive prostate cancer progression., PMID:34611310
Establishment and characterization of NCC-LGFMS1-C1: a novel patient-derived cell line of low-grade fibromyxoid sarcoma., PMID:34535876
CREB3L2 Modulates Nerve Growth Factor-Induced Cell Differentiation., PMID:34421533
Somatic Mutation Profiling of Papillary Thyroid Carcinomas by Whole-exome Sequencing and Its Relationship with Clinical Characteristics., PMID:34104084
Comparative Analysis of CREB3 and CREB3L2 Protein Expression in HEK293 Cells., PMID:33803345
MicroRNA-92b-3p promotes the progression of liver fibrosis by targeting CREB3L2 through the JAK/STAT signaling pathway., PMID:33618248
Transcriptomic-based toxicological investigations of ethanol to human umbilical vein endothelial cells., PMID:33058231
Toxic effects of endoplasmic reticulum stress transducer BBF2H7-derived small peptide fragments on neuronal cells., PMID:33010207
Low-grade fibromyxoid sarcoma in inguinal region: A case report., PMID:32988706
Growth inhibition associated with disruption of the actin cytoskeleton by Latrunculin A in rhabdomyosarcoma cells., PMID:32898143
Sclerosing Epithelioid Fibrosarcoma: A Distinct Sarcoma With Aggressive Features., PMID:32769431
Sclerosing epithelioid fibrosarcoma: cytologic characterization with histologic, immunohistologic, molecular, and clinical correlation of 8 cases., PMID:32624384
Genome-wide identification and comparison of differentially expressed profiles of miRNAs and lncRNAs with associated ceRNA networks in the gonads of Chinese soft-shelled turtle, Pelodiscus sinensis., PMID:32600250
Low-grade fibromyxoid sarcoma: a clinicopathologic and molecular study of 10 genetically confirmed cases., PMID:31949672
Production of BBF2H7-derived small peptide fragments via endoplasmic reticulum stress-dependent regulated intramembrane proteolysis., PMID:31914686
Recurrent Fusions Between YAP1 and KMT2A in Morphologically Distinct Neoplasms Within the Spectrum of Low-grade Fibromyxoid Sarcoma and Sclerosing Epithelioid Fibrosarcoma., PMID:31913156
Clinical and molecular characterization of primary sclerosing epithelioid fibrosarcoma of bone and review of the literature., PMID:31675134
Promotion of Axon Growth by the Secreted End of a Transcription Factor., PMID:31597097
Pituitary cell translation and secretory capacities are enhanced cell autonomously by the transcription factor Creb3l2., PMID:31481663
Decreased Activity of the Ghrhr and Gh Promoters Causes Dominantly Inherited GH Deficiency in Humanized GH1 Mouse Models., PMID:31436800
CREB3 Transcription Factors: ER-Golgi Stress Transducers as Hubs for Cellular Homeostasis., PMID:31334233
Low-grade fibromyxoid sarcoma of the extremities: a clinicopathologic study of 24 cases and review of the literature., PMID:30509048
Site-1 protease function is essential for the generation of antibody secreting cells and reprogramming for secretory activity., PMID:30254311
Clear Cell Odontogenic Carcinoma: Occurrence of EWSR1-CREB1 as Alternative Fusion Gene to EWSR1-ATF1., PMID:30047065
Site-1 protease deficiency causes human skeletal dysplasia due to defective inter-organelle protein trafficking., PMID:30046013
For research use only. Not for human or drug use.
