Catalog No.
YHA68201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln71-Asp186
Predicted molecular weight
14.76 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O43482
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CT86, Cancer/testis antigen 86, OIP5, OIP-5, Protein Mis18-beta, Opa-interacting protein 5, MIS18B
The lncRNA OIP5-AS1/miR-181a-5p Axis Promotes TGF-β1-induced Fibrosis in HK2 Cells., PMID:40424490
Downregulation of OIP5-AS1 inhibits apoptosis in myocardial ischemia/reperfusion injury via modulating the MiR-145-5p/ROCK1 axis., PMID:40392837
LncRNA OIP5-AS1 promotes immune evasion in abdominal aortic aneurysm cells by recruiting MDSCs and inhibiting CD8 + T cells through STK24 upregulation., PMID:40384846
LncRNA OIP5-AS1/miR-186-5p/NLRP3 Axis Contributes to Sepsis-Induced Kidney Injury Through Enhancing NLRP3 Inflammasome Activation., PMID:40371556
LncRNA OIP5-AS1 Modulates the Biological Behaviour of Lung Cancer Cells by Regulating the hsa-miR-29b-3p/ZIC5 Axis., PMID:40344305
Exosomal lncRNAs in the Tumor Angiogenesis: As Therapeutic Targets in Cancer Treatment., PMID:40165644
Differential miRNA expression in neural-enriched extracellular vesicles as potential biomarker for frontotemporal dementia and bipolar disorder., PMID:40064379
Exploration of Circadian Clock-Related Genes in the Pathogenesis of Psoriatic Arthritis to Identify Potential Therapeutic Targets From Multi-Omics Insight: A Mendelian Randomization Study., PMID:40062439
Long non-coding RNA OIP5-AS1 protects neurons from ischemia-reperfusion injury and inhibits neuronal apoptosis through TAB-2., PMID:39693936
Spatial Expression of Long Non-Coding RNAs in Human Brains of Alzheimer's Disease., PMID:39554066
GATA1-activated lncRNA OIP5-AS1 and GAS5 promote pyroptosis to exacerbate asthma through regulating miR-136-5p/LIFR axis., PMID:39535503
Lipid Nanoparticle-Mediated Oip5-as1 Delivery Preserves Mitochondrial Function in Myocardial Ischemia/Reperfusion Injury by Inhibiting the p53 Pathway., PMID:39485791
Novel repurposing of sulfasalazine for the treatment of adrenocortical carcinomas, probably through the SLC7A11/xCT-hsa-miR-92a-3p-OIP5-AS1 network pathway., PMID:39424480
Identification of key lncRNAs associated with oxaliplatin resistance in colorectal cancer cells and isolated exosomes: From In-Silico prediction to In-Vitro validation., PMID:39401197
DMRT3-mediated lncRNA OIP5-AS1 promotes the pyroptosis of bronchial epithelial cells by binding with EIF4A3 to enhance YAP mRNA stability., PMID:39287912
In-Silico and In-Vitro Investigation of Key Long Non-coding RNAs Involved in 5-Fluorouracil Resistance in Colorectal Cancer Cells: Analyses Highlighting NEAT1 and MALAT1 as Contributors., PMID:39246994
N6-methyladenosine modification of linc-OIP5 confers paclitaxel resistance in breast cancer through a DDX5-dependent mechanism., PMID:39209141
Engineered targeting OIP5 sensitizes bladder cancer to chemotherapy resistance via TRIP12-PPP1CB-YBX1 axis., PMID:39155295
β-TrCP-Mediated Proteolysis of Mis18β Prevents Mislocalization of CENP-A and Chromosomal Instability., PMID:39135477
OIP5-AS1 enhances the malignant characteristics and resistance to chemotherapy of pancreatic cancer cells by targeting miR-30d-5p/MARCH8., PMID:39050450
Natural products and long noncoding RNA signatures in gallbladder cancer: a review focuses on pathogenesis, diagnosis, and drug resistance., PMID:39028332
OIP5-AS1/miR-455-3p/microfibril-associated protein 2 axis exacerbates the progression of thyroid carcinoma., PMID:38988919
LncRNA OIP5-AS1 Upregulates the Cyclin D2 Levels to Promote Metastasis of Breast Cancer by Targeting miR-150-5p., PMID:38888699
Exploring IDI2-AS1, OIP5-AS1, and LITATS1: Changes in Long Non-coding RNAs Induced by the Poly I:C Stimulation., PMID:38866523
[H3K27 acetylation promotes lncRNA OIP5-AS1 transcription and induces apoptosis of nasal epithelial cells in allergic rhinitis through up-regulation of TLR4]., PMID:38790098
lncRNA Oip5-as1 inhibits excessive mitochondrial fission in myocardial ischemia/reperfusion injury by modulating DRP1 phosphorylation., PMID:38745296
Knockdown of CENPM activates cGAS-STING pathway to inhibit ovarian cancer by promoting pyroptosis., PMID:38693472
Hepatitis B virus X protein promotes tumor glycolysis by downregulating lncRNA OIP5-AS1/HKDC1 in HCC., PMID:38636768
Stoichiometry of long noncoding RNA interactions with other RNAs: Insights from OIP5-AS1., PMID:38576135
YTHDC1 promotes the malignant progression of gastric cancer by promoting ROD1 translocation to the nucleus., PMID:38573528
Mitotic Spindle Positioning (MISP) Facilitates Colorectal Cancer Progression by Forming a Complex with Opa Interacting Protein 5 (OIP5) and Activating the JAK2-STAT3 Signaling Pathway., PMID:38474305
Synergistic effects of tetramethylpyrazine and astragaloside IV on spinal cord injury via alteration of astrocyte A1/A2 polarization through the Sirt1-NF-κB pathway., PMID:38461631
lncRNA OIP5-AS1 promotes mitophagy to alleviate osteoarthritis by upregulating PPAR-γ to activate the AMPK/Akt/mTOR pathway., PMID:38441253
Nanoparticles transfected with plasmid-encoded lncRNA-OIP5-AS1 inhibit renal ischemia-reperfusion injury in mice via the miR-410-3p/Nrf2 axis., PMID:38419565
Integrated analysis and validation of ferroptosis-related genes and immune infiltration in acute myocardial infarction., PMID:38402377
Identification and validation of a copper homeostasis-related gene signature for the predicting prognosis of breast cancer patients via integrated bioinformatics analysis., PMID:38326441
The Clinical Significance and the Potential Regulatory Mechanism of the LncRNA OIP5-AS1 in Paediatric Severe Community-Acquired Pneumonia Blood Through the MiR-150-5p/PDCD4 Axis., PMID:38294019
Activating transcription factor 3 is a new biomarker correlation with renal clear cell carcinoma progression., PMID:38248871
Downregulation of PTPRT elevates the expression of survivin and promotes the proliferation, migration, and invasion of lung adenocarcinoma., PMID:38216925
Differential expressions and potential clinical values of lncRNAs in the plasma exosomes of rheumatoid arthritis., PMID:38194746
Identification of a lncRNA/circRNA-miRNA-mRNA ceRNA Network in Alzheimer's Disease., PMID:38176923
OIP5-AS1/CD147/TRPM7 axis promotes gastric cancer metastasis by regulating apoptosis related PI3K-Akt signaling., PMID:38156103
LncRNA OIP5-AS1 Targets the miR-140-5p/UBR5 Cascade to Promote the Development of Gastric Cancer., PMID:38112962
Exosomal OIP5-AS1 attenuates cerebral ischemia-reperfusion injury by negatively regulating TXNIP protein stability and inhibiting neuronal pyroptosis., PMID:38103409
Engineering redirected NF-κB/OIP5 expression programs to enhance tumor responses to chemotherapy in bladder cancer., PMID:37993335
Down-regulation of OIP5-AS1 inhibits obesity-induced myocardial pyroptosis and miR-22/NLRP3 inflammasome axis., PMID:37904706
N6-methyladenosine modification of OIP5-AS1 promotes glycolysis, tumorigenesis, and metastasis of gastric cancer by inhibiting Trim21-mediated hnRNPA1 ubiquitination and degradation., PMID:37897508
The role of OIP5 in the carcinogenesis and progression of ovarian cancer., PMID:37660035
Identification of Hub Genes and Upstream Regulatory Factors Based on Cell Adhesion in Triple-negative Breast Cancer by Integrated Bioinformatical Analysis., PMID:37351977
lncRNA OIP5-AS1 attenuates the osteoarthritis progression in IL-1β-stimulated chondrocytes., PMID:37333451
For research use only. Not for human or drug use.
