Catalog No.
YHB71401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser282-Ser339
Predicted molecular weight
19.11 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O95674
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Phosphatidate cytidylyltransferase 2, CDP-diglyceride pyrophosphorylase 2, CDS2, CDP-DG synthase 2, CDP-diacylglycerol synthase 2, CDP-DAG synthase 2, CDP-diglyceride synthase 2, CDS 2, CTP:phosphatidate cytidylyltransferase 2
Nr-CWS regulates METTL3-mediated m6A modification of CDS2 mRNA in vascular endothelial cells and has prognostic significance., PMID:39424634
Transcription Factor GmERF105 Negatively Regulates Salt Stress Tolerance in Arabidopsis thaliana., PMID:37631217
ASL mRNA-LNP Therapeutic for the Treatment of Argininosuccinic Aciduria Enables Survival Benefit in a Mouse Model., PMID:37371829
Hepatic CDP-diacylglycerol synthase 2 deficiency causes mitochondrial dysfunction and promotes rapid progression of NASH and fibrosis., PMID:36546079
Comparative chloroplast genomes and phylogenetic relationships of Aglaonema modestum and five variegated cultivars of Aglaonema., PMID:36054201
Cytidinediphosphate diacylglycerol synthase-Mediated phosphatidic acid metabolism is crucial for early embryonic development of Arabidopsis., PMID:35877676
Metabolic routing maintains the unique fatty acid composition of phosphoinositides., PMID:35712788
Chicken CDS2 isoforms presented distinct spatio-temporal expression pattern and regulated by insulin in a breed-specific manner., PMID:35504066
A novel RNA pol II CTD interaction site on the mRNA capping enzyme is essential for its allosteric activation., PMID:33684220
Phospholipid dynamics in ex vivo lung cancer and normal lung explants., PMID:33408336
Mutation screening of the UBE3A gene in Chinese Han population with autism., PMID:33308194
Ecotopic over-expression of PoCHS from Paeonia ostii altered the fatty acids composition and content in Arabidopsis thaliana., PMID:33247451
CDP-Diacylglycerol Synthases (CDS): Gateway to Phosphatidylinositol and Cardiolipin Synthesis., PMID:32117988
Establishment and characterization of NCC-CDS2-C1: a novel patient-derived cell line of CIC-DUX4 sarcoma., PMID:31898195
Selection of Reliable Reference Genes for Analysis of Gene Expression in Spinal Cord during Rat Postnatal Development and after Injury., PMID:31861889
CDP-DAG synthase 1 and 2 regulate lipid droplet growth through distinct mechanisms., PMID:31548309
Endothelial CDS2 deficiency causes VEGFA-mediated vascular regression and tumor inhibition., PMID:31501519
Prioritization of metabolic genes as novel therapeutic targets in estrogen-receptor negative breast tumors using multi-omics data and text mining., PMID:31231467
Phosphatidylinositol synthesis at the endoplasmic reticulum., PMID:31173893
Sustained phospholipase C stimulation of H9c2 cardiomyoblasts by vasopressin induces an increase in CDP-diacylglycerol synthase 1 (CDS1) through protein kinase C and cFos., PMID:30862571
p53 cooperates with SIRT6 to regulate cardiolipin de novo biosynthesis., PMID:30237540
Mitochondrial CDP-diacylglycerol synthase activity is due to the peripheral protein, TAMM41 and not due to the integral membrane protein, CDP-diacylglycerol synthase 1., PMID:29253589
CDP-diacylglycerol synthases regulate the growth of lipid droplets and adipocyte development., PMID:26946540
[Change in the prevalence of obesity phenotypes and cardiometabolic disorders among children aged 6- 17 in Beijing during 2004- 2013]., PMID:26792501
Distinct properties of the two isoforms of CDP-diacylglycerol synthase., PMID:25375833
The identification of novel targets of miR-16 and characterization of their biological functions in cancer cells., PMID:23941513
Extraplastidial cytidinediphosphate diacylglycerol synthase activity is required for vegetative development in Arabidopsis thaliana., PMID:23711240
CDP-diacylglycerol synthetase-controlled phosphoinositide availability limits VEGFA signaling and vascular morphogenesis., PMID:22649102
High levels of RNA-editing site conservation amongst 15 laboratory mouse strains., PMID:22524474
Underexpression of miR-224 in methotrexate resistant human colon cancer cells., PMID:21864507
Rapid decrease in active tension generated by C2C12 myotubes after termination of artificial exercise., PMID:21120590
Two closely related genes of Arabidopsis encode plastidial cytidinediphosphate diacylglycerol synthases essential for photoautotrophic growth., PMID:20442275
Translocation of p53 to mitochondria is regulated by its lipid binding property to anionic phospholipids and it participates in cell death control., PMID:20126473
The effects of pyridoxine deficiency and supplementation on hematological profiles, lymphocyte function, and hepatic cytochrome P450 in B6C3F1 mice., PMID:19637937
Abscisic acid has a key role in modulating diverse plant-pathogen interactions., PMID:19571312
Regulation of cardiolipin biosynthesis by fatty acid transport protein-1 IN HEK 293 cells., PMID:19523918
Cardiolipin biosynthesis and remodeling enzymes are altered during development of heart failure., PMID:19001357
Prolonged androgen receptor loading onto chromatin and the efficient recruitment of p160 coactivators contribute to androgen-independent growth of prostate cancer cells., PMID:18780293
STAT-3 regulates surfactant phospholipid homeostasis in normal lung and during endotoxin-mediated lung injury., PMID:18369093
The Zn- and Cd-clusters of recombinant mammalian MT1 and MT4 metallothionein domains include sulfide ligands., PMID:17018875
Identification of MglA-regulated genes reveals novel virulence factors in Francisella tularensis., PMID:17000729
Interleukin-17 receptor-like gene is a novel antiapoptotic gene highly expressed in androgen-independent prostate cancer., PMID:16397230
Isolation and characterization of murine Cds (CDP-diacylglycerol synthase) 1 and 2., PMID:16023307
Stimulation of cardiac cardiolipin biosynthesis by PPARalpha activation., PMID:14594999
Evidence for a type III secretion system in Chlamydophila psittaci., PMID:24757810
Differential expression of cold- and diet-specific genes encoding two carp liver delta 9-acyl-CoA desaturase isoforms., PMID:12388470
Evidence for the secretion of Chlamydia trachomatis CopN by a type III secretion mechanism., PMID:11123678
Identification and characterization of CDS2, a mammalian homolog of the Drosophila CDP-diacylglycerol synthase gene., PMID:9889000
The role of CDP-diacylglycerol synthetase and phosphatidylinositol synthase activity levels in the regulation of cellular phosphatidylinositol content., PMID:9407135