Catalog No.
YHC08702
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr68-Leu107
Predicted molecular weight
32.80 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P04279
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Semenogelin-1, Semenogelin I, SGI, SEMG1, Cancer/testis antigen 103, SEMG
[Effects of silencing the SEMG1 protein on the cycle and apoptosis of GC-1 spg cells]. PMID: 33377697
Expressions of miR-525-3p and its target gene SEMG1 in the spermatozoa of patients with asthenozoospermia. PMID: 30575326
SEMG1/2 augment energy metabolism of tumor cells. PMID: 33311447
Human Semenogelin 1 Promotes Sperm Survival in the Mouse Female Reproductive Tract. PMID: 32486486
Loss of calcium in human spermatozoa via EPPIN, the semenogelin receptor. PMID: 22075473
Cancer-testis antigens, semenogelins 1 and 2, exhibit different anti-proliferative effects on human lung adenocarcinoma cells. PMID: 33101710
Interacting proteins on human spermatozoa: adaptive evolution of the binding of semenogelin I to EPPIN. PMID: 24312623
Blocking serine protease activity prevents semenogelin degradation leading to hyperviscous semen in humans. PMID: 35098308
SEMG1 may be the candidate gene for idiopathic asthenozoospermia. PMID: 23289976
Characterization of EPPIN's semenogelin I binding site: a contraceptive drug target. PMID: 22699487
Molecular evolution of the semenogelin 1 and 2 and mating system in gibbons. PMID: 30575018
Binding interactions of epididymal protease inhibitor and semenogelin-1: a homology modeling, docking and molecular dynamics simulation study. PMID: 31404433
Reproduction and immunity-driven natural selection in the human WFDC locus. PMID: 23292442
The common marmoset (Callithrix jacchus) has two very similar semenogelin genes as the result of gene conversion. PMID: 17192513
Characterization of an eppin protein complex from human semen and spermatozoa. PMID: 17567961
Protein Fingerprinting of Seminal Plasma Reveals Dysregulation of Exosome-Associated Proteins in Infertile Men with Unilateral Varicocele. PMID: 31081293
Dissecting EPPIN protease inhibitor domains in sperm motility and fertilizing ability: repercussions for male contraceptive development. PMID: 34792600
Emerging roles of cancer-testis antigenes, semenogelin 1 and 2, in neoplastic cells. PMID: 33966049
Hominoid seminal protein evolution and ancestral mating behavior. PMID: 18561295
Evolution of the hominoid semenogelin genes, the major proteins of ejaculated semen. PMID: 14629036
Genes encoding WFDC- and Kunitz-type protease inhibitor domains: are they related? PMID: 21936822
A locus on chromosome 20 encompassing genes that are highly expressed in the epididymis. PMID: 17589793
Re-Analysis of Published Datasets in Search of Novel Urogenital Diseases Biomarkers. PMID: 36177616
Mutations in two short noncoding mononucleotide repeats in most microsatellite-unstable colorectal cancers. PMID: 15930278
Evaluation of forensic examination of extremely aged seminal stains. PMID: 24844186
Comprehensive proteomics analysis of exosomes derived from human seminal plasma. PMID: 28914500
Investigation of male infertility using quantitative comparative proteomics. PMID: 25355644
Sexual selection and the adaptive evolution of mammalian ejaculate proteins. PMID: 18032407
Identification of Urinary Biomarkers for Exercise-Induced Immunosuppression by iTRAQ Proteomics. PMID: 32047808
Development of a prognostic signature of patients with esophagus adenocarcinoma by using immune-related genes. PMID: 34724890
Comparative sequence analyses reveal rapid and divergent evolutionary changes of the WFDC locus in the primate lineage. PMID: 17267810
A novel application of cell-free seminal mRNA: non-invasive identification of the presence of germ cells or complete obstruction in men with azoospermia. PMID: 22286264
Expression study of three secretory proteins (prostatic secretory protein of 94 amino acids, probasin, and seminal vesicle secretion II) in dysplastic and neoplastic rat prostates. PMID: 12746832
SEMG-1 expression in early stage chronic lymphocytic leukemia. PMID: 19241194
Birth-and-death of KLK3 and KLK2 in primates: evolution driven by reproductive biology. PMID: 23204305
Analysis of recombinant human semenogelin as an inhibitor of human sperm motility. PMID: 19889947
Characterization of seminal plasma proteomic alterations associated with the IVF and rescue-ICSI pregnancy in assisted reproduction. PMID: 31364287
Evaluation of mRNA-based approach for identification of saliva and semen. PMID: 19036626
Baicalin Attenuates Continuous Activation of β-Catenin Induced by Lipopolysaccharide (LPS) and Depression Complicated by Infertility in Male Rats. PMID: 35432561
Identification of coding region SNPs from specific and sensitive mRNA biomarkers for the deconvolution of the semen donor in a body fluid mixture. PMID: 33610949
Central T cell tolerance: Identification of tissue-restricted autoantigens in the thymus HLA-DR peptidome. PMID: 25911201
Sequence variation at KLK and WFDC clusters and its association to semen hyperviscosity and other male infertility phenotypes. PMID: 27827323
A rapid and easy electrophoretic method for detecting biochemical loci of rat (Rattus norvegices). PMID: 8726146
Measles virus N protein inhibits host translation by binding to eIF3-p40. PMID: 17686838
In vitro reconstitution of antimicrobial pathogen activity by expressed recombinant bovine lactoferrin N-terminal peptide in Escherichia coli. PMID: 17466115
SARS coronavirus nucleocapsid immunodominant T-cell epitope cluster is common to both exogenous recombinant and endogenous DNA-encoded immunogens. PMID: 16387339
Quantitative image cytometry of hepatocytes expressing gamma-glutamyl transpeptidase and glutathione S-transferase in diethylnitrosamine-initiated rats treated with phenobarbital and/or phthalate esters. PMID: 1352315
In-silico analysis of recombinant protein vaccines based on the spike protein of Indonesian SARS-CoV-2 through a reverse vaccinology approach. PMID: 35250426
Detection of severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein in human serum using a localized surface plasmon coupled fluorescence fiber-optic biosensor. PMID: 19660929
Wheat germ cell-free expression system for protein production. PMID: 18429309
Trimodal GSTT1 and GSTM1 genotyping assay by real-time PCR. PMID: 16011037
[Preparation and identification of a monoclonal antibody against recombinant human L-type pyruvate kinase N]. PMID: 20848771