Please ensure Javascript is enabled for purposes of website accessibility
Home / Products / Recombinant Protein / Other Proteins

Recombinant Human PTBP3 Protein, N-His

Catalog #:   YHB73801 Specific References (96) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: O95758
Protein length: Gly356-Ile552
Overview

Catalog No.

YHB73801

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Gly356-Ile552

Predicted molecular weight

24.28 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

O95758

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

Regulator of differentiation 1, Polypyrimidine tract-binding protein 3, Rod1, PTBP3, ROD1

Data Image
  • SDS-PAGE
    SDS PAGE for Recombinant Human PTBP3 protein
References

LncRNA BCRT1 promotes breast cancer progression by targeting miR-1303/PTBP3 axis. PMID: 32384893

PTBP3 modulates P53 expression and promotes colorectal cancer cell proliferation by maintaining UBE4A mRNA stability. PMID: 35136024

PTBP3-Mediated Regulation of ZEB1 mRNA Stability Promotes Epithelial-Mesenchymal Transition in Breast Cancer. PMID: 29187406

PTBP3 regulates proliferation of lung squamous cell carcinoma cells via CDC25A-mediated cell cycle progression. PMID: 35016691

PTBP3 contributes to colorectal cancer growth and metastasis via translational activation of HIF-1α. PMID: 31291975

PTBP3 mediates TGF-β-induced EMT and metastasis of lung adenocarcinoma. PMID: 35323096

PTBP3 promotes malignancy and hypoxia-induced chemoresistance in pancreatic cancer cells by ATG12 up-regulation. PMID: 31989778

PTBP3 contributes to the metastasis of gastric cancer by mediating CAV1 alternative splicing. PMID: 29752441

The RNA-binding protein ROD1/PTBP3 cotranscriptionally defines AID-loading sites to mediate antibody class switch in mammalian genomes. PMID: 30143796

Inhibition of polypyrimidine tract-binding protein 3 induces apoptosis and cell cycle arrest, and enhances the cytotoxicity of 5- fluorouracil in gastric cancer cells. PMID: 28222070

Multivalent interactions with RNA drive recruitment and dynamics in biomolecular condensates in Xenopus oocytes. PMID: 35982794

PTBP3 splicing factor promotes hepatocellular carcinoma by destroying the splicing balance of NEAT1 and pre-miR-612. PMID: 30068940

PTBP3 promotes migration of non-small cell lung cancer through regulating E-cadherin in EMT signaling pathway. PMID: 32477006

Generation of functionally distinct isoforms of PTBP3 by alternative splicing and translation initiation. PMID: 25940628

PTBP3 Induced Inhibition of Differentiation of Gastric Cancer Cells Through Alternative Splicing of Id1. PMID: 32974175

New Insights Into PTBP3 in Human Cancers: Immune Cell Infiltration, TMB, MSI, PDCD1 and m6A Markers. PMID: 35359851

Circular RNA circ_0006089 promotes the progression of gastric cancer by regulating the miR-143-3p/PTBP3 axis and PI3K/AKT signaling pathway. PMID: 35844201

LncRNA Meg3 protects endothelial function by regulating the DNA damage response. PMID: 30476192

The effects of PTBP3 silencing on the proliferation and differentiation of MKN45 human gastric cancer cells. PMID: 25119103

MiR-384 inhibits proliferation and migration of trophoblast cells via targeting PTBP3. PMID: 32512528

Long non-coding RNA SLC25A21-AS1 inhibits the development of epithelial ovarian cancer by specifically inducing PTBP3 degradation. PMID: 36717926

Chromosome Conformation Capture Reveals Two Elements That Interact with the PTBP3 (ROD1) Transcription Start Site. PMID: 30634466

Identification of Immune Cells and Key Genes associated with Alzheimer's Disease. PMID: 34975305

PTBPs: An immunomodulatory-related prognostic biomarker in pan-cancer. PMID: 36203873

Expression analysis of the polypyrimidine tract binding protein (PTBP1) and its paralogs PTBP2 and PTBP3 during Xenopus tropicalis embryogenesis. PMID: 23124965

Myosins and MyomiR Network in Patients with Obstructive Hypertrophic Cardiomyopathy. PMID: 36140281

Essential requirement for polypyrimidine tract binding proteins 1 and 3 in the maturation and maintenance of mature B cells in mice. PMID: 34214192

Human polypyrimidine tract-binding protein interacts with mitochondrial tRNA(Thr) in the cytosol. PMID: 26657638

LPS Administration Impacts Glial Immune Programs by Alternative Splicing. PMID: 35204777

PTB/nPTB: master regulators of neuronal fate in mammals. PMID: 30310857

ROD1 is a seedless target gene of hypoxia-induced miR-210. PMID: 23024754

Zika virus dysregulates the expression of astrocytic genes involved in neurodevelopment. PMID: 33891593

Efficient mitotic checkpoint signaling depends on integrated activities of Bub1 and the RZZ complex. PMID: 30782962

Molecular profiling of premalignant lesions in lung squamous cell carcinomas identifies mechanisms involved in stepwise carcinogenesis. PMID: 24618292

Methylation of the genes ROD1, NLRC5, and HKR1 is associated with aging in Hainan centenarians. PMID: 29394898

A new function of ROD1 in nonsense-mediated mRNA decay. PMID: 22575643

Position Specific Alternative Splicing and Gene Expression Profiles Along the Tonotopic Axis of Chick Cochlea. PMID: 34568429

Human cardiac stem cell differentiation is regulated by a mircrine mechanism. PMID: 21403094

Transcriptional profile of primary astrocytes expressing ALS-linked mutant SOD1. PMID: 18683239

Crossregulation and functional redundancy between the splicing regulator PTB and its paralogs nPTB and ROD1. PMID: 17679092

MicroRNA-210 regulates cell proliferation and apoptosis by targeting regulator of differentiation 1 in glioblastoma cells. PMID: 26443314

Isolation of a mammalian homologue of a fission yeast differentiation regulator. PMID: 10207106

De novo prediction of PTBP1 binding and splicing targets reveals unexpected features of its RNA recognition and function. PMID: 24499931

Regulator of differentiation 1 (ROD1) binds to the amphipathic C-terminal peptide of thrombospondin-4 and is involved in its mitogenic activity. PMID: 19441079

Type 3-specific synthase of Streptococcus pneumoniae (Cap3B) directs type 3 polysaccharide biosynthesis in Escherichia coli and in pneumococcal strains of different serotypes. PMID: 8760798

[Difference of gene expression profile in human gastric cancer grafted onto nude mice treated with WCA]. PMID: 18161298

Deciphering alternative splicing patterns during cell fate transition of fast chemical reprogramming., PMID:40490773

Targeting PTBP3-Mediated Alternative Splicing of COX11 Induces Cuproptosis for Inhibiting Gastric Cancer Peritoneal Metastasis., PMID:40270362

Extracellular vesicles in lung donor plasma: Potential indicators of donor organ quality., PMID:40118141

RNA-Binding Protein Signature in Proliferative Cardiomyocytes: A Cross-Species Meta-Analysis from Mouse, Pig, and Human Transcriptomic Profiling Data., PMID:40001614

PTBP3 Mediates IL-18 Exon Skipping to Promote Immune Escape in Gallbladder Cancer., PMID:39116343

Non-coding RNA yREX3 from human extracellular vesicles exerts macrophage-mediated cardioprotection via a novel gene-methylating mechanism., PMID:38865332

YTHDC1 promotes the malignant progression of gastric cancer by promoting ROD1 translocation to the nucleus., PMID:38573528

Parameter Identifiability in PDE Models of Fluorescence Recovery After Photobleaching., PMID:38430382

CircSEPT9 promotes breast cancer progression by regulating PTBP3 expression via sponging miR-625-5p., PMID:38409914

Polypyrimidine tract-binding protein 3/insulin-like growth factor 2 mRNA-binding proteins 3/high-mobility group A1 axis promotes renal cancer growth and metastasis., PMID:38405614

Subfunctionalisation of paralogous genes and evolution of differential codon usage preferences: The showcase of polypyrimidine tract binding proteins., PMID:37667674

MiR-297 inhibits tumour progression of liver cancer by targeting PTBP3., PMID:37633911

Long non-coding RNA SLC25A21-AS1 inhibits the development of epithelial ovarian cancer by specifically inducing PTBP3 degradation., PMID:36717926

PTBPs: An immunomodulatory-related prognostic biomarker in pan-cancer., PMID:36203873

Myosins and MyomiR Network in Patients with Obstructive Hypertrophic Cardiomyopathy., PMID:36140281

Multivalent interactions with RNA drive recruitment and dynamics in biomolecular condensates in Xenopus oocytes., PMID:35982794

Circular RNA circ_0006089 promotes the progression of gastric cancer by regulating the miR-143-3p/PTBP3 axis and PI3K/AKT signaling pathway., PMID:35844201

New Insights Into PTBP3 in Human Cancers: Immune Cell Infiltration, TMB, MSI, PDCD1 and m6A Markers., PMID:35359851

PTBP3 mediates TGF-β-induced EMT and metastasis of lung adenocarcinoma., PMID:35323096

LPS Administration Impacts Glial Immune Programs by Alternative Splicing., PMID:35204777

PTBP3 modulates P53 expression and promotes colorectal cancer cell proliferation by maintaining UBE4A mRNA stability., PMID:35136024

PTBP3 regulates proliferation of lung squamous cell carcinoma cells via CDC25A-mediated cell cycle progression., PMID:35016691

Identification of Immune Cells and Key Genes associated with Alzheimer's Disease., PMID:34975305

Position Specific Alternative Splicing and Gene Expression Profiles Along the Tonotopic Axis of Chick Cochlea., PMID:34568429

Essential requirement for polypyrimidine tract binding proteins 1 and 3 in the maturation and maintenance of mature B cells in mice., PMID:34214192

Zika virus dysregulates the expression of astrocytic genes involved in neurodevelopment., PMID:33891593

PTBP3 Induced Inhibition of Differentiation of Gastric Cancer Cells Through Alternative Splicing of Id1., PMID:32974175

MiR-384 inhibits proliferation and migration of trophoblast cells via targeting PTBP3., PMID:32512528

PTBP3 promotes migration of non-small cell lung cancer through regulating E-cadherin in EMT signaling pathway., PMID:32477006

LncRNA BCRT1 promotes breast cancer progression by targeting miR-1303/PTBP3 axis., PMID:32384893

PTBP3 promotes malignancy and hypoxia-induced chemoresistance in pancreatic cancer cells by ATG12 up-regulation., PMID:31989778

PTBP3 contributes to colorectal cancer growth and metastasis via translational activation of HIF-1α., PMID:31291975

Efficient mitotic checkpoint signaling depends on integrated activities of Bub1 and the RZZ complex., PMID:30782962

Chromosome Conformation Capture Reveals Two Elements That Interact with the PTBP3 (ROD1) Transcription Start Site., PMID:30634466

LncRNA Meg3 protects endothelial function by regulating the DNA damage response., PMID:30476192

PTB/nPTB: master regulators of neuronal fate in mammals., PMID:30310857

The RNA-binding protein ROD1/PTBP3 cotranscriptionally defines AID-loading sites to mediate antibody class switch in mammalian genomes., PMID:30143796

PTBP3 splicing factor promotes hepatocellular carcinoma by destroying the splicing balance of NEAT1 and pre-miR-612., PMID:30068940

PTBP3 contributes to the metastasis of gastric cancer by mediating CAV1 alternative splicing., PMID:29752441

Methylation of the genes ROD1, NLRC5, and HKR1 is associated with aging in Hainan centenarians., PMID:29394898

PTBP3-Mediated Regulation of ZEB1 mRNA Stability Promotes Epithelial-Mesenchymal Transition in Breast Cancer., PMID:29187406

Inhibition of polypyrimidine tract-binding protein 3 induces apoptosis and cell cycle arrest, and enhances the cytotoxicity of 5- fluorouracil in gastric cancer cells., PMID:28222070

Human polypyrimidine tract-binding protein interacts with mitochondrial tRNA(Thr) in the cytosol., PMID:26657638

MicroRNA-210 regulates cell proliferation and apoptosis by targeting regulator of differentiation 1 in glioblastoma cells., PMID:26443314

Generation of functionally distinct isoforms of PTBP3 by alternative splicing and translation initiation., PMID:25940628

The effects of PTBP3 silencing on the proliferation and differentiation of MKN45 human gastric cancer cells., PMID:25119103

Molecular profiling of premalignant lesions in lung squamous cell carcinomas identifies mechanisms involved in stepwise carcinogenesis., PMID:24618292

De novo prediction of PTBP1 binding and splicing targets reveals unexpected features of its RNA recognition and function., PMID:24499931

Expression analysis of the polypyrimidine tract binding protein (PTBP1) and its paralogs PTBP2 and PTBP3 during Xenopus tropicalis embryogenesis., PMID:23124965

ROD1 is a seedless target gene of hypoxia-induced miR-210., PMID:23024754

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

Contact Information

Order: order@antibodysystem.com

Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

Need help with your order?

Find out more about placing an order here

Recombinant Human PTBP3 Protein, N-His [YHB73801]
Terms of sale Website terms of use Cookie policy Privacy
Copyright © 2025 AntibodySystem SAS. All Rights Reserved.            All Products are for Research Use Only