Evolution of human apolipoprotein E (APOE) isoforms: Gene structure, protein function and interaction with dietary factors. PMID: 28647612
APOE and Alzheimer's disease: advances in genetics, pathophysiology, and therapeutic approaches. PMID: 33340485
ApoE and Neurodegenerative Diseases in Aging. PMID: 30232753
The role of APOE on lipid homeostasis and inflammation in normal brains. PMID: 28258087
Expression and secretion of apoE isoforms in astrocytes and microglia during inflammation. PMID: 33556209
APOE in the bullseye of neurodegenerative diseases: impact of the APOE genotype in Alzheimer's disease pathology and brain diseases. PMID: 36153580
Isoform- and cell-state-specific lipidation of ApoE in astrocytes. PMID: 35235798
APOE interacts with ACE2 inhibiting SARS-CoV-2 cellular entry and inflammation in COVID-19 patients. PMID: 35915083
Understanding the Role of ApoE Fragments in Alzheimer's Disease. PMID: 30225748
Apolipoprotein E, Receptors, and Modulation of Alzheimer's Disease. PMID: 28434655
Apolipoprotein E in lipoprotein metabolism, health and cardiovascular disease. PMID: 30598326
Apolipoprotein E: structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases. PMID: 25173806
Apoprotein E and Reverse Cholesterol Transport. PMID: 30404132
A serum protein signature of APOE genotypes in centenarians. PMID: 31385390
APOE*ε4 promotes synucleinopathy. PMID: 32107475
APOE genetics influence murine gut microbiome. PMID: 35115575
ApoE in atherosclerosis : a protein with multiple hats. PMID: 10938002
Protein oligomerization as a metabolic control mechanism: Application to apoE. PMID: 30701627
Fragmentation of brain apolipoprotein E (ApoE) and its relevance in Alzheimer's disease. PMID: 32364519
APOE signaling in neurodegenerative diseases: an integrative approach targeting APOE coding and noncoding variants for disease intervention. PMID: 33647674
APOE Genotypes Modulate Inflammation Independently of Their Effect on Lipid Metabolism. PMID: 36361733
APOE at the BBB: Pericyte-Derived Apolipoprotein E4 Diminishes Endothelial Cell Barrier Function. PMID: 31869265
The interaction of amyloid-beta with ApoE. PMID: 15709483
Signaling pathway factors expression in renal tissue of apoE-knockout mice. PMID: 26096163
Inconstant apolipoprotein E (ApoE)-like immunoreactivity in amyloid beta protein deposits: relationship with APOE genotype in aging brain and Alzheimer's disease. PMID: 8841664
Glial fibrillary acidic protein-apolipoprotein E (apoE) transgenic mice: astrocyte-specific expression and differing biological effects of astrocyte-secreted apoE3 and apoE4 lipoproteins. PMID: 9547235
Profile and regulation of apolipoprotein E (ApoE) expression in the CNS in mice with targeting of green fluorescent protein gene to the ApoE locus. PMID: 16687490
Sex differences in the formation of atherosclerosis lesion in apoE-/-mice and the effect of 17β-estrodiol on protein S-nitrosylation. PMID: 29665642
Effects of different isoforms of apoE on aggregation of the α-synuclein protein implicated in Parkinson's disease. PMID: 26921451
Apolipoprotein E in Cardiometabolic and Neurological Health and Diseases. PMID: 36077289
Impact of apoE genotype on oxidative stress, inflammation and disease risk. PMID: 18203129
The role of apolipoprotein E in neurodegeneration and cardiovascular disease. PMID: 24754513
Links between ApoE, brain cholesterol metabolism, tau and amyloid beta-peptide in patients with cognitive impairment. PMID: 20658997
Physical interaction of ApoE with amyloid precursor protein independent of the amyloid Abeta region in vitro. PMID: 9593736
Human APOE isoform-dependent effects on brain beta-amyloid levels in PDAPP transgenic mice. PMID: 19474305
Role of ApoE in conformation-prone diseases and atherosclerosis. PMID: 16903824
Few serum proteins mediate APOE's association with dementia. PMID: 28291794
ApoE: the role of conserved residues in defining function. PMID: 25377861
The cell biology and physiologic relevance of ApoE recycling. PMID: 11150725
The Role of Apolipoprotein E Isoforms in Alzheimer's Disease. PMID: 30775980
In vitro and in cellulo ApoE particle formation, isolation, and characterization. PMID: 36595894
Apolipoprotein E O-glycosylation is associated with amyloid plaques and APOE genotype. PMID: 37072097
A multi-hit hypothesis for an APOE4-dependent pathophysiological state. PMID: 35510513
Association of APOE Serum Levels and APOE ε2, ε3, and ε4 Alleles with Optic Neuritis. PMID: 35885971
Apolipoprotein ε7 allele in memory complaints: insights through protein structure prediction. PMID: 28744113
Astrocyte lipoproteins, effects of apoE on neuronal function, and role of apoE in amyloid-beta deposition in vivo. PMID: 10936884
The Complex Role of Apolipoprotein E in Alzheimer's Disease: an Overview and Update. PMID: 27647307
Association of apoE gene expression and its gene polymorphism with nephrotic syndrome susceptibility: a meta-analysis of experimental and human studies. PMID: 22760259
Self-assembly of HEK cell-secreted ApoE particles resembles ApoE enrichment of lipoproteins as a ligand for the LDL receptor-related protein. PMID: 16401069
Cross-talk between apolipoprotein E and cytokines. PMID: 21772670
The influence of apoE-deficiency and LDL-receptor-deficiency on the HDL subpopulation profile in mice and in humans. PMID: 24529120
Apolipoprotein E imbalance in the cerebrospinal fluid of Alzheimer's disease patients. PMID: 36324176
Apolipoproteins and aging: emerging mechanisms. PMID: 12067591
Lipid composition dependent binding of apolipoprotein E signal peptide: Importance of membrane cholesterol in protein trafficking. PMID: 36228459
Apolipoprotein E: from lipid transport to neurobiology. PMID: 20854843
Endocytosis of apoE-EGFP by primary human brain cultures. PMID: 12377208
Role of estrogen in women's Alzheimer's disease risk as modified by APOE. PMID: 36420620
Loss of cellular inhibitor of apoptosis protein 2 reduces atherosclerosis in atherogenic apoE-/- C57BL/6 mice on high-fat diet. PMID: 24072531
Apolipoprotein E and oxidative stress in brain with relevance to Alzheimer's disease. PMID: 32036033
Mechanisms of enhanced macrophage apoE secretion by oxidized LDL. PMID: 9186915
Mechanisms linking apolipoprotein E isoforms with cardiovascular and neurological diseases. PMID: 20531185
S-nitrosylation of ApoE in Alzheimer's disease. PMID: 21443265
Conformational Reorganization of Apolipoprotein E Triggered by Phospholipid Assembly. PMID: 33979165
Apolipoprotein E polymorphism and susceptibility to Alzheimer's disease. PMID: 7729825
New and confirmatory evidence of an association between APOE genotype and baseline C-reactive protein in dyslipidemic individuals. PMID: 15530909
Understanding Dengue Virus Capsid Protein Interaction with Key Biological Targets. PMID: 26161501
Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease. PMID: 22393530
Influence of metformin on mitochondrial subproteome in the brain of apoE knockout mice. PMID: 26712380
Amyloid A protein amyloidosis induced in apolipoprotein-E-deficient mice. PMID: 9327723
Gene sequences regulating the production of apoE and cerebral palsy of variable severity. PMID: 24786335
Apolipoprotein E Facilitates Amyloid-β Oligomer-Induced Tau Phosphorylation. PMID: 32065788
Endogenous ApoE expression modulates adipocyte triglyceride content and turnover. PMID: 17130485
ApoE synthesis in human neuroblastoma cells. PMID: 9440124
A Biophysical Approach to the Identification of Novel ApoE Chemical Probes. PMID: 30700058
Is epsilon4 the ancestral human apoE allele? PMID: 10604434
Apolipoprotein E and the apolipoprotein E-deficient mouse. PMID: 8527231
ApoE deficiency: markedly decreased levels of cellular ApoE mRNA. PMID: 3004475
A multifaceted role for apoE in the clearance of beta-amyloid across the blood-brain barrier. PMID: 22572854
The role of apolipoprotein E in Alzheimer's disease: pharmacogenomic target selection. PMID: 10899434
Measurement of apolipoprotein E (apoE) in cerebrospinal fluid. PMID: 10823584
Cholesterol and apoe: a target for Alzheimer's disease therapeutics. PMID: 16266288
Molecular design and modeling of protein-heparin interactions. PMID: 1762571
Apolipoprotein E: possible therapeutic target for atherosclerosis. PMID: 12769659
Molecular pathogenesis of apolipoprotein E-mediated amyloidosis in late-onset Alzheimer's disease. PMID: 11212354
The role of apolipoprotein E in bone metabolism. PMID: 21798384
The cell and molecular biology of apolipoprotein E synthesis by macrophages. PMID: 3525037
Exercise modulates APOE expression in brain cortex of female APOE3 and APOE4 targeted replacement mice. PMID: 36434832
Recombinant neural protein PrP can bind with both recombinant and native apolipoprotein E in vitro. PMID: 16953297
The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor. PMID: 15863833
Age-related binding of proximal region of ApoE promoter to nuclear proteins of mouse cerebral cortex. PMID: 21643978
Plaque attack. Mice without ApoE and related protein unexpectedly accumulate beta-amyloid deposits. PMID: 14749520
Analysis of apolipoprotein E nuclear localization using green fluorescent protein and biotinylation approaches. PMID: 17961126
An ApoE-Abeta inhibition complex in Abeta fibril extension. PMID: 8939715
APOE epsilon 3/ epsilon 4 heterozygotes have an elevated proportion of apolipoprotein E4 in cerebrospinal fluid relative to plasma, independent of Alzheimer's disease diagnosis. PMID: 12957508
Apolipoprotein E binds to and reduces serum levels of DNA-mimicking, pyrrolated proteins. PMID: 31167785
Lipoprotein glomerulopathy induced by ApoE-Sendai is different from glomerular lesions in aged apoE-deficient mice. PMID: 19459027
Apolipoprotein (apo) E genotype and apoE concentration determine binding of normal very low density lipoproteins to HepG2 cell surface receptors. PMID: 8808766
Apolipoprotein E forms stable complexes with recombinant Alzheimer's disease beta-amyloid precursor protein. PMID: 9224643
Apolipoprotein E4: an allele associated with many diseases. PMID: 10766403
[Apo-E phenotype]. PMID: 10543062
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