Catalog No.
YHK91501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro65-Arg105
Predicted molecular weight
32.93 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9NYZ2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
SLC25A37, Solute carrier family 25 member 37, Mitochondrial iron transporter 1, MSCP, Mitochondrial solute carrier protein, MFRN, Mitoferrin-1
Identification of key genes in coronary artery disease: an integrative approach based on weighted gene co-expression network analysis and their correlation with immune infiltration. PMID: 33686958
PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism. PMID: 30100261
Pan-cancer genetic analysis of cuproptosis and copper metabolism-related gene set. PMID: 36276096
Combinatorial GxGxE CRISPR screen identifies SLC25A39 in mitochondrial glutathione transport linking iron homeostasis to OXPHOS. PMID: 35513392
Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria. PMID: 19805291
Identification of SLC25A37 as a major depressive disorder risk gene. PMID: 27643475
The mitochondrial metal transporters mitoferrin1 and mitoferrin2 are required for liver regeneration and cell proliferation in mice. PMID: 32518166
RNA m6A Demethylase ALKBH5 Protects Against Pancreatic Ductal Adenocarcinoma via Targeting Regulators of Iron Metabolism. PMID: 34733841
Iron regulatory protein-1 protects against mitoferrin-1-deficient porphyria. PMID: 24509859
Distinct iron architecture in SF3B1-mutant myelodysplastic syndrome patients is linked to an SLC25A37 splice variant with a retained intron. PMID: 24854990
TNFα-Induced Expression of Transport Protein Genes in HUVEC Cells Is Associated with Enhanced Expression of Transcription Factor Genes RELB and NFKB2 of the Non-Canonical NF-κB Pathway. PMID: 29658079
Identification of iron metabolism-related genes in the circulation and myocardium of patients with sepsis via applied bioinformatics analysis. PMID: 36937929
Mitoferrin-1 is required for brain energy metabolism and hippocampus-dependent memory. PMID: 31563673
Mitochondria-related gene expression changes are associated with fatigue in patients with nonmetastatic prostate cancer receiving external beam radiation therapy. PMID: 23047795
Dysregulation of iron protein expression in the G93A model of amyotrophic lateral sclerosis. PMID: 23178912
Dynamic Control of Enhancer Repertoires Drives Lineage and Stage-Specific Transcription during Hematopoiesis. PMID: 26766440
The Role of Hemoglobin Subunit Delta in the Immunopathy of Multiple Sclerosis: Mitochondria Matters. PMID: 34504491
RNA expression profiling in sulfamethoxazole-treated patients with a range of in vitro lymphocyte cytotoxicity phenotypes. PMID: 29511567
Iron metabolism gene expression and prognostic features of hepatocellular carcinoma. PMID: 30076742
A dynamic intron retention program enriched in RNA processing genes regulates gene expression during terminal erythropoiesis. PMID: 26531823
The impact of microRNA expression on cellular proliferation. PMID: 24609542
Identification of distal cis-regulatory elements at mouse mitoferrin loci using zebrafish transgenesis. PMID: 21248200
Analysis of genetic and clinical factors associated with buprenorphine response. PMID: 34488071
Identification of an iron-responsive subtype in two children diagnosed with relapsing-remitting multiple sclerosis using whole exome sequencing. PMID: 30963028
Mitoferrin is essential for erythroid iron assimilation. PMID: 16511496
MiR-7 mediates mitochondrial impairment to trigger apoptosis and necroptosis in Rhabdomyosarcoma. PMID: 32810522
Mitochondrial quality control mediated by PINK1 and PRKN: links to iron metabolism and tumor immunity. PMID: 30252570
Strong correlation of ferrochelatase enzymatic activity with Mitoferrin-1 mRNA in lymphoblasts of patients with protoporphyria. PMID: 30391163
Assessment of hematopoietic failure due to Rpl11 deficiency in a zebrafish model of Diamond-Blackfan anemia by deep sequencing. PMID: 24341334
Differential expression of genes related to mitochondrial biogenesis and bioenergetics in fatigued prostate cancer men receiving external beam radiation therapy. PMID: 24786901
Abnormal mitoferrin-1 expression in patients with erythropoietic protoporphyria. PMID: 21627978
Dimeric ferrochelatase bridges ABCB7 and ABCB10 homodimers in an architecturally defined molecular complex required for heme biosynthesis. PMID: 30765471
The role of hepcidin, GDF15, and mitoferrin-1 in iron metabolism of polycythemia vera and essential thrombocytosis patients. PMID: 30761871
Systematic Surveys of Iron Homeostasis Mechanisms Reveal Ferritin Superfamily and Nucleotide Surveillance Regulation to be Modified by PINK1 Absence. PMID: 33023155
Deregulation of genes related to iron and mitochondrial metabolism in refractory anemia with ring sideroblasts. PMID: 25955609
Abcb10 role in heme biosynthesis in vivo: Abcb10 knockout in mice causes anemia with protoporphyrin IX and iron accumulation. PMID: 24421385
Transethnic meta-analysis suggests genetic variation in the HEME pathway influences potassium response in patients treated with hydrochlorothiazide. PMID: 25201287
Impact of Body Mass Index, Age, Prostate Volume, and Genetic Polymorphisms on Prostate-specific Antigen Levels in a Control Population. PMID: 26850968
Fourteen novel human members of mitochondrial solute carrier family 25 (SLC25) widely expressed in the central nervous system. PMID: 16949250
Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells. PMID: 25428262
For research use only. Not for human or drug use.
