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Recombinant Human SLC25A37 Protein, N-GST & C-His

Catalog #:   YHK91501 Specific References (89) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: Q9NYZ2
Protein length: Pro65-Arg105
Overview

Catalog No.

YHK91501

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Pro65-Arg105

Predicted molecular weight

32.93 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

Q9NYZ2

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

SLC25A37, Solute carrier family 25 member 37, Mitochondrial iron transporter 1, MSCP, Mitochondrial solute carrier protein, MFRN, Mitoferrin-1

Data Image
  • SDS-PAGE
    SDS PAGE for Recombinant Human SLC25A37 protein
References

Identification of key genes in coronary artery disease: an integrative approach based on weighted gene co-expression network analysis and their correlation with immune infiltration. PMID: 33686958

PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism. PMID: 30100261

Pan-cancer genetic analysis of cuproptosis and copper metabolism-related gene set. PMID: 36276096

Combinatorial GxGxE CRISPR screen identifies SLC25A39 in mitochondrial glutathione transport linking iron homeostasis to OXPHOS. PMID: 35513392

Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria. PMID: 19805291

Identification of SLC25A37 as a major depressive disorder risk gene. PMID: 27643475

The mitochondrial metal transporters mitoferrin1 and mitoferrin2 are required for liver regeneration and cell proliferation in mice. PMID: 32518166

RNA m6A Demethylase ALKBH5 Protects Against Pancreatic Ductal Adenocarcinoma via Targeting Regulators of Iron Metabolism. PMID: 34733841

Iron regulatory protein-1 protects against mitoferrin-1-deficient porphyria. PMID: 24509859

Distinct iron architecture in SF3B1-mutant myelodysplastic syndrome patients is linked to an SLC25A37 splice variant with a retained intron. PMID: 24854990

TNFα-Induced Expression of Transport Protein Genes in HUVEC Cells Is Associated with Enhanced Expression of Transcription Factor Genes RELB and NFKB2 of the Non-Canonical NF-κB Pathway. PMID: 29658079

Identification of iron metabolism-related genes in the circulation and myocardium of patients with sepsis via applied bioinformatics analysis. PMID: 36937929

Mitoferrin-1 is required for brain energy metabolism and hippocampus-dependent memory. PMID: 31563673

Mitochondria-related gene expression changes are associated with fatigue in patients with nonmetastatic prostate cancer receiving external beam radiation therapy. PMID: 23047795

Dysregulation of iron protein expression in the G93A model of amyotrophic lateral sclerosis. PMID: 23178912

Dynamic Control of Enhancer Repertoires Drives Lineage and Stage-Specific Transcription during Hematopoiesis. PMID: 26766440

The Role of Hemoglobin Subunit Delta in the Immunopathy of Multiple Sclerosis: Mitochondria Matters. PMID: 34504491

RNA expression profiling in sulfamethoxazole-treated patients with a range of in vitro lymphocyte cytotoxicity phenotypes. PMID: 29511567

Iron metabolism gene expression and prognostic features of hepatocellular carcinoma. PMID: 30076742

A dynamic intron retention program enriched in RNA processing genes regulates gene expression during terminal erythropoiesis. PMID: 26531823

The impact of microRNA expression on cellular proliferation. PMID: 24609542

Identification of distal cis-regulatory elements at mouse mitoferrin loci using zebrafish transgenesis. PMID: 21248200

Analysis of genetic and clinical factors associated with buprenorphine response. PMID: 34488071

Identification of an iron-responsive subtype in two children diagnosed with relapsing-remitting multiple sclerosis using whole exome sequencing. PMID: 30963028

Mitoferrin is essential for erythroid iron assimilation. PMID: 16511496

MiR-7 mediates mitochondrial impairment to trigger apoptosis and necroptosis in Rhabdomyosarcoma. PMID: 32810522

Mitochondrial quality control mediated by PINK1 and PRKN: links to iron metabolism and tumor immunity. PMID: 30252570

Strong correlation of ferrochelatase enzymatic activity with Mitoferrin-1 mRNA in lymphoblasts of patients with protoporphyria. PMID: 30391163

Assessment of hematopoietic failure due to Rpl11 deficiency in a zebrafish model of Diamond-Blackfan anemia by deep sequencing. PMID: 24341334

Differential expression of genes related to mitochondrial biogenesis and bioenergetics in fatigued prostate cancer men receiving external beam radiation therapy. PMID: 24786901

Abnormal mitoferrin-1 expression in patients with erythropoietic protoporphyria. PMID: 21627978

Dimeric ferrochelatase bridges ABCB7 and ABCB10 homodimers in an architecturally defined molecular complex required for heme biosynthesis. PMID: 30765471

The role of hepcidin, GDF15, and mitoferrin-1 in iron metabolism of polycythemia vera and essential thrombocytosis patients. PMID: 30761871

Systematic Surveys of Iron Homeostasis Mechanisms Reveal Ferritin Superfamily and Nucleotide Surveillance Regulation to be Modified by PINK1 Absence. PMID: 33023155

Deregulation of genes related to iron and mitochondrial metabolism in refractory anemia with ring sideroblasts. PMID: 25955609

Abcb10 role in heme biosynthesis in vivo: Abcb10 knockout in mice causes anemia with protoporphyrin IX and iron accumulation. PMID: 24421385

Transethnic meta-analysis suggests genetic variation in the HEME pathway influences potassium response in patients treated with hydrochlorothiazide. PMID: 25201287

Impact of Body Mass Index, Age, Prostate Volume, and Genetic Polymorphisms on Prostate-specific Antigen Levels in a Control Population. PMID: 26850968

Fourteen novel human members of mitochondrial solute carrier family 25 (SLC25) widely expressed in the central nervous system. PMID: 16949250

Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells. PMID: 25428262

PINK1-deficiency facilitates mitochondrial iron accumulation and colon tumorigenesis., PMID:39512202

Genetics of Cardiac Aging Implicate Organ-Specific Variation., PMID:39148824

Characterizing mitochondrial features in osteoarthritis through integrative multi-omics and machine learning analysis., PMID:39026663

Mitoferrin2 is a synthetic lethal target for chromosome 8p deleted cancers., PMID:38886830

Image-based quantification of mitochondrial iron uptake via Mitoferrin-2., PMID:38692382

The cell fate regulator DACH1 modulates ferroptosis through affecting P53/SLC25A37 signaling in fibrotic disease., PMID:38437058

Congenital asplenia impairs heme-iron recycling during erythropoiesis in zebrafish., PMID:38040044

Identification and Analysis of Neutrophil Extracellular Trap-Related Genes in Osteoarthritis by Bioinformatics and Experimental Verification., PMID:37671131

RNA sequencing and bioinformatics analysis of differentially expressed genes in the peripheral serum of ankylosing spondylitis patients., PMID:37254181

Identification of iron metabolism-related genes in the circulation and myocardium of patients with sepsis via applied bioinformatics analysis., PMID:36937929

Pan-cancer genetic analysis of cuproptosis and copper metabolism-related gene set., PMID:36276096

Combinatorial GxGxE CRISPR screen identifies SLC25A39 in mitochondrial glutathione transport linking iron homeostasis to OXPHOS., PMID:35513392

RNA m6A Demethylase ALKBH5 Protects Against Pancreatic Ductal Adenocarcinoma via Targeting Regulators of Iron Metabolism., PMID:34733841

The Role of Hemoglobin Subunit Delta in the Immunopathy of Multiple Sclerosis: Mitochondria Matters., PMID:34504491

Analysis of genetic and clinical factors associated with buprenorphine response., PMID:34488071

Identification of key genes in coronary artery disease: an integrative approach based on weighted gene co-expression network analysis and their correlation with immune infiltration., PMID:33686958

Systematic Surveys of Iron Homeostasis Mechanisms Reveal Ferritin Superfamily and Nucleotide Surveillance Regulation to be Modified by PINK1 Absence., PMID:33023155

MiR-7 mediates mitochondrial impairment to trigger apoptosis and necroptosis in Rhabdomyosarcoma., PMID:32810522

The mitochondrial metal transporters mitoferrin1 and mitoferrin2 are required for liver regeneration and cell proliferation in mice., PMID:32518166

Mitoferrin-1 is required for brain energy metabolism and hippocampus-dependent memory., PMID:31563673

Identification of an iron-responsive subtype in two children diagnosed with relapsing-remitting multiple sclerosis using whole exome sequencing., PMID:30963028

Dimeric ferrochelatase bridges ABCB7 and ABCB10 homodimers in an architecturally defined molecular complex required for heme biosynthesis., PMID:30765471

The role of hepcidin, GDF15, and mitoferrin-1 in iron metabolism of polycythemia vera and essential thrombocytosis patients., PMID:30761871

Strong correlation of ferrochelatase enzymatic activity with Mitoferrin-1 mRNA in lymphoblasts of patients with protoporphyria., PMID:30391163

Mitochondrial quality control mediated by PINK1 and PRKN: links to iron metabolism and tumor immunity., PMID:30252570

PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism., PMID:30100261

Iron metabolism gene expression and prognostic features of hepatocellular carcinoma., PMID:30076742

TNFα-Induced Expression of Transport Protein Genes in HUVEC Cells Is Associated with Enhanced Expression of Transcription Factor Genes RELB and NFKB2 of the Non-Canonical NF-κB Pathway., PMID:29658079

RNA expression profiling in sulfamethoxazole-treated patients with a range of in vitro lymphocyte cytotoxicity phenotypes., PMID:29511567

Identification of SLC25A37 as a major depressive disorder risk gene., PMID:27643475

Impact of Body Mass Index, Age, Prostate Volume, and Genetic Polymorphisms on Prostate-specific Antigen Levels in a Control Population., PMID:26850968

Dynamic Control of Enhancer Repertoires Drives Lineage and Stage-Specific Transcription during Hematopoiesis., PMID:26766440

A dynamic intron retention program enriched in RNA processing genes regulates gene expression during terminal erythropoiesis., PMID:26531823

Deregulation of genes related to iron and mitochondrial metabolism in refractory anemia with ring sideroblasts., PMID:25955609

Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells., PMID:25428262

Transethnic meta-analysis suggests genetic variation in the HEME pathway influences potassium response in patients treated with hydrochlorothiazide., PMID:25201287

Distinct iron architecture in SF3B1-mutant myelodysplastic syndrome patients is linked to an SLC25A37 splice variant with a retained intron., PMID:24854990

Differential expression of genes related to mitochondrial biogenesis and bioenergetics in fatigued prostate cancer men receiving external beam radiation therapy., PMID:24786901

The impact of microRNA expression on cellular proliferation., PMID:24609542

Iron regulatory protein-1 protects against mitoferrin-1-deficient porphyria., PMID:24509859

Abcb10 role in heme biosynthesis in vivo: Abcb10 knockout in mice causes anemia with protoporphyrin IX and iron accumulation., PMID:24421385

Assessment of hematopoietic failure due to Rpl11 deficiency in a zebrafish model of Diamond-Blackfan anemia by deep sequencing., PMID:24341334

Dysregulation of iron protein expression in the G93A model of amyotrophic lateral sclerosis., PMID:23178912

Mitochondria-related gene expression changes are associated with fatigue in patients with nonmetastatic prostate cancer receiving external beam radiation therapy., PMID:23047795

Abnormal mitoferrin-1 expression in patients with erythropoietic protoporphyria., PMID:21627978

Identification of distal cis-regulatory elements at mouse mitoferrin loci using zebrafish transgenesis., PMID:21248200

Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria., PMID:19805291

Fourteen novel human members of mitochondrial solute carrier family 25 (SLC25) widely expressed in the central nervous system., PMID:16949250

Mitoferrin is essential for erythroid iron assimilation., PMID:16511496

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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Recombinant Human SLC25A37 Protein, N-GST & C-His [YHK91501]
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