Inflammation and Infection in Pain and the Role of GPR37. PMID: 36430912
GPR37 regulates macrophage phagocytosis and resolution of inflammatory pain. PMID: 30010619
GPR37 promotes cancer growth by binding to CDK6 and represents a new theranostic target in lung adenocarcinoma. PMID: 35934193
Activation of GPR37 in macrophages confers protection against infection-induced sepsis and pain-like behaviour in mice. PMID: 33731716
Orphan G Protein Coupled Receptors in Affective Disorders. PMID: 32599826
Ecto-GPR37: a potential biomarker for Parkinson's disease. PMID: 33637132
Drug Discovery Opportunities at the Endothelin B Receptor-Related Orphan G Protein-Coupled Receptors, GPR37 and GPR37L1. PMID: 26635605
Osteocalcin attenuates oligodendrocyte differentiation and myelination via GPR37 signaling in the mouse brain. PMID: 34678058
GPR37 protein trafficking to the plasma membrane regulated by prosaposin and GM1 gangliosides promotes cell viability. PMID: 24371137
G protein-coupled receptor GPR37-like 1 regulates adult oligodendrocyte generation. PMID: 34601807
Orphan G protein-coupled receptors: The role in CNS disorders. PMID: 29268243
Mouse Mutants of Gpr37 and Gpr37l1 Receptor Genes: Disease Modeling Applications. PMID: 35457105
Cytosolic GPR37, but not GPR37L1, multimerization and its reversal by Parkin: A live cell imaging study. PMID: 34822195
GPR37 and Related Receptors: Disease Regulation. PMID: 37047695
Folding Underlies Bidirectional Role of GPR37/Pael-R in Parkinson Disease. PMID: 28629580
GPR37 surface expression enhancement via N-terminal truncation or protein-protein interactions. PMID: 19799451
Protective effects of GPR37 via regulation of inflammation and multiple cell death pathways after ischemic stroke in mice. PMID: 31268736
Parkinson's disease-associated GPR37 receptor regulates cocaine-mediated synaptic depression in corticostriatal synapses. PMID: 28007645
Quantitative Proteomics Reveal an Altered Pattern of Protein Expression in Brain Tissue from Mice Lacking GPR37 and GPR37L1. PMID: 31903766
Spatiotemporal Control of GPR37 Signaling and Its Behavioral Effects by Optogenetics. PMID: 29643766
GPR37 Signaling Modulates Migration of Olfactory Ensheathing Cells and Gonadotropin Releasing Hormone Cells in Mice. PMID: 31143101
Mice lacking Gpr37 exhibit decreased expression of the myelin-associated glycoprotein MAG and increased susceptibility to demyelination. PMID: 28642167
GPR37 is processed in the N-terminal ectodomain by ADAM10 and furin. PMID: 34042202
GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin. PMID: 23690594
The role of parkinson's disease-associated receptor GPR37 in the hippocampus: functional interplay with the adenosinergic system. PMID: 25824528
GPR37 Receptors and Megalencephalic Leukoencephalopathy with Subcortical Cysts. PMID: 35628339
GM1 Is Cytoprotective in GPR37-Expressing Cells and Downregulates Signaling. PMID: 34884663
Glio- and neuro-protection by prosaposin is mediated by orphan G-protein coupled receptors GPR37L1 and GPR37. PMID: 30260505
Emerging Roles for the Orphan GPCRs, GPR37 and GPR37 L1, in Stroke Pathophysiology. PMID: 35409385
Parkinson's disease-associated receptor GPR37 is an ER chaperone for LRP6. PMID: 28341812
GPR37 modulates progenitor cell dynamics in a mouse model of ischemic stroke. PMID: 33839144
Functional GPR37 trafficking protects against toxicity induced by 6-OHDA, MPP+ or rotenone in a catecholaminergic cell line. PMID: 23121049
Osteocalcin Alleviates Lipopolysaccharide-Induced Acute Inflammation via Activation of GPR37 in Macrophages. PMID: 35625743
Molecular cloning and chromosomal localization of the mouse Gpr37 gene encoding an orphan G-protein-coupled peptide receptor expressed in brain and testis. PMID: 9799598
The role of the orphan G protein-coupled receptor 37 (GPR37) in multiple myeloma cells. PMID: 24290813
Mice lacking the Parkinson's related GPR37/PAEL receptor show non-motor behavioral phenotypes: age and gender effect. PMID: 23574697
Deficits in Motor Performance, Neurotransmitters and Synaptic Plasticity in Elderly and Experimental Parkinsonian Mice Lacking GPR37. PMID: 32292338
The Parkinson's disease-associated GPR37 receptor interacts with striatal adenosine A2A receptor controlling its cell surface expression and function in vivo. PMID: 28842709
[Up-regulation of GPR37 promotes the proliferation of human glioma U251 cells]. PMID: 29973325
A low level of GPR37 is associated with human hepatocellular carcinoma progression and poor patient survival. PMID: 25169131
The neuropeptide head activator is a high-affinity ligand for the orphan G-protein-coupled receptor GPR37. PMID: 16443751
Cloning of GPR37, a gene located on chromosome 7 encoding a putative G-protein-coupled peptide receptor, from a human frontal brain EST library. PMID: 9339362
The Parkinson's-disease-associated receptor GPR37 undergoes metalloproteinase-mediated N-terminal cleavage and ectodomain shedding. PMID: 26869225
CASPR2 forms a complex with GPR37 via MUPP1 but not with GPR37(R558Q), an autism spectrum disorder-related mutation. PMID: 25977097
Modulation of Dhh signaling and altered Sertoli cell function in mice lacking the GPR37-prosaposin receptor. PMID: 25609427
Induction of macroautophagy by overexpression of the Parkinson's disease-associated GPR37 receptor. PMID: 19218498
G protein-coupled receptor 37 (GPR37) emerges as an important modulator of adenosinergic transmission in the striatum. PMID: 31290447
G protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination. PMID: 26961174
Comparative analysis of protein-protein interaction networks in metastatic breast cancer. PMID: 35045088
GPR37 and GPR37L1 differently interact with dopamine 2 receptors in live cells. PMID: 30423289
Mutation in Parkinson disease-associated, G-protein-coupled receptor 37 (GPR37/PaelR) is related to autism spectrum disorder. PMID: 23251443
Expression of the G protein-coupled receptor (GPR) 37 and GPR37L1 in the mouse digestive system. PMID: 33208571
The Parkinson's disease-associated GPR37 receptor-mediated cytotoxicity is controlled by its intracellular cysteine-rich domain. PMID: 23398388
GPR37 associates with the dopamine transporter to modulate dopamine uptake and behavioral responses to dopaminergic drugs. PMID: 17519329
Multipathway In Vitro Pharmacological Characterization of Specialized Proresolving G Protein-Coupled Receptors. PMID: 35125345
REG4 promotes peritoneal metastasis of gastric cancer through GPR37. PMID: 27036049
The role of orphan G protein-coupled receptors in the pathophysiology of multiple sclerosis: A review. PMID: 30904492
Systematic protein-protein interaction mapping for clinically relevant human GPCRs. PMID: 28298427
Spatiotemporal Dynamics of the Molecular Expression Pattern and Intercellular Interactions in the Glial Scar Response to Spinal Cord Injury. PMID: 35788904
Accelerating the reversal of inflammatory pain with NPD1 and its receptor GPR37. PMID: 30010628
Chronic adenosine A2A receptor blockade induces locomotor sensitization and potentiates striatal LTD IN GPR37-deficient mice. PMID: 30578680
Absence of the GPR37/PAEL receptor impairs striatal Akt and ERK2 phosphorylation, DeltaFosB expression, and conditioned place preference to amphetamine and cocaine. PMID: 21372109
Altered dopamine signaling and MPTP resistance in mice lacking the Parkinson's disease-associated GPR37/parkin-associated endothelin-like receptor. PMID: 15218106
Adenosine A2A receptor-mediated control of pilocarpine-induced tremulous jaw movements is Parkinson's disease-associated GPR37 receptor-dependent. PMID: 25862943
The protective role of prosaposin and its receptors in the nervous system. PMID: 25130661
The protein interacting with C-kinase (PICK1) interacts with and attenuates parkin-associated endothelial-like (PAEL) receptor-mediated cell death. PMID: 24749734
G protein-linked signaling pathways in bipolar and major depressive disorders. PMID: 24391664
G protein-coupled receptor 37-like 1 modulates astrocyte glutamate transporters and neuronal NMDA receptors and is neuroprotective in ischemia. PMID: 28795439
Chlorogenic acid enhances alveolar macrophages phagocytosis in acute respiratory distress syndrome by activating G protein-coupled receptor 37 (GPR 37). PMID: 36194973
Expression patterns of prosaposin and its receptors, G protein-coupled receptor (GPR) 37 and GPR37L1 mRNAs, in the chick inner ear. PMID: 36750499
Impaired Aversive Memory Formation in GPR37L1KO Mice. PMID: 36430766
S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration. PMID: 16724068
Age- and sex-associated changes in prosaposin and its receptors in the lacrimal glands of rats. PMID: 31215019
Macroautophagy of the GPR37 orphan receptor and Parkinson disease-associated neurodegeneration. PMID: 19398891
Identification of prognosis-related hub genes of ovarian cancer through bioinformatics analyses and experimental verification. PMID: 36086731
Expression of prosaposin and its G protein-coupled receptor (GPR) 37 in mouse cochlear and vestibular nuclei. PMID: 36696997
Pael receptor, endoplasmic reticulum stress, and Parkinson's disease. PMID: 14579121
Prosaposin and its receptors are differentially expressed in the salivary glands of male and female rats. PMID: 29656342
[Physiological Roles of Ubiquitin Ligases Related to the Endoplasmic Reticulum]. PMID: 27252059
Neurodegeneration: how does parkin prevent Parkinson's disease? PMID: 12842030
Use of viral vectors to create animal models for Parkinson's disease. PMID: 22227451
The Effect of Early Life Stress on Emotional Behaviors in GPR37KO Mice. PMID: 35008836
G protein-coupled receptor genes in the FANTOM2 database. PMID: 12819145
[Possible involvement of HRD1 (ubiquitin E3 ligase) in neurodegenerative diseases]. PMID: 19443960
New Advances in Targeting the Resolution of Inflammation: Implications for Specialized Pro-Resolving Mediator GPCR Drug Discovery. PMID: 32259091
[Molecular pharmacological studies on the protection mechanism against endoplasmic reticulum stress-induced neurodegenerative disease]. PMID: 23208051
Expanding insights on the involvement of endoplasmic reticulum stress in Parkinson's disease. PMID: 17465880
The expression of prosaposin and its receptors, GRP37 and GPR37L1, are increased in the developing dorsal root ganglion. PMID: 34379697
A novel modelling mechanism of PAEL receptor and GABARAPL2 interaction involved in Parkinson's disease. PMID: 29496607
Expression patterns of prosaposin and its receptors, G protein-coupled receptor (GPR) 37 and GPR37L1, in the mouse olfactory organ. PMID: 37075680
Cloning and developmental expression of a chick G-protein-coupled receptor SCGPR1. PMID: 17251065
Anatomical and histological profiling of orphan G-protein-coupled receptor expression in gastrointestinal tract of C57BL/6J mice. PMID: 19763624
Expression of prosaposin and its receptors in the rat cerebellum after kainic acid injection. PMID: 30135931
Indole-3-propionic acid has chemical chaperone activity and suppresses endoplasmic reticulum stress-induced neuronal cell death. PMID: 31378367
Proteomic profiling reveals antitumor effects of RT2 peptide on a human colon carcinoma xenograft mouse model. PMID: 35032485
Alterations in hepatic miRNA expression during negative energy balance in postpartum dairy cattle. PMID: 24428929
Vitamin D Metabolites Inhibit Hepatitis C Virus and Modulate Cellular Gene Expression. PMID: 26594646
What's all the RAVE about receptor internalization? PMID: 10482227
GzESTY as an optimized cell-based assay for initial steps in GPCR deorphanization., PMID:40374633
Neuroprotectin D1 and GPR37 protect against chemotherapy-induced peripheral neuropathy and the transition from acute to chronic pain., PMID:40287118
Pharmacological and resting state fMRI reveal Osteocalcin's effects on mouse brain regions with high Gpr37 and Gpr158 expression., PMID:40128223
GPR37 Activation Alleviates Bone Cancer Pain via the Inhibition of Osteoclastogenesis and Neuronal Hyperexcitability., PMID:39965073
[Effect of Yuxuebi Tablets on mice with inflammatory pain based on GPR37-mediated inflammation resolution]., PMID:39929659
Oligodendrocytes drive neuroinflammation and neurodegeneration in Parkinson's disease via the prosaposin-GPR37-IL-6 axis., PMID:39913287
GPR37-enhanced ubiquitination of ATP1A1 inhibits tumor progression and radiation resistance in esophageal squamous cell carcinoma., PMID:39730361
GPR37 and its neuroprotective mechanisms: bridging osteocalcin signaling and brain function., PMID:39633709
GPR37 promotes colorectal cancer against ferroptosis by reprogramming lipid metabolism via p38-SCD1 axis., PMID:39306652
GPR37 processing in neurodegeneration: a potential marker for Parkinson's Disease progression rate., PMID:39256360
Emerging roles of the G-protein-coupled receptor 37 in neurological diseases and pain., PMID:39244010
Selenomethionine Promotes Milk Protein and Fat Synthesis and Proliferation of Mammary Epithelial Cells through the GPR37-mTOR-S6K1 Signaling., PMID:39177123
Gz Enhanced Signal Transduction assaY (GZESTY) for GPCR deorphanization., PMID:39091869
Role of orphan G-protein coupled receptors in tissue ischemia: A comprehensive review., PMID:38906238
Gpr37 modulates the severity of inflammation-induced GI dysmotility by regulating enteric reactive gliosis., PMID:38645163
The role of orphan G protein-coupled receptors in pain., PMID:38590871
The myelination-associated G protein-coupled receptor 37 is regulated by Zfp488, Nkx2.2, and Sox10 during oligodendrocyte differentiation., PMID:38546197
Multiplex Proteomics in the Identification of Potential Biomarkers of Very Severe Sinusoidal Obstruction Syndrome/Veno-Occlusive Disease in Allogeneic Hematopoietic Cell Transplant Patients Treated with Defibrotide., PMID:38330921
Impact of miR-29c-3p in the Nucleus Accumbens on Methamphetamine-Induced Behavioral Sensitization and Neuroplasticity-Related Proteins., PMID:38256016
Intranasal administration of recombinant prosaposin attenuates neuronal apoptosis through GPR37/PI3K/Akt/ASK1 pathway in MCAO rats., PMID:38114054
Cascading effects of hypobaric hypoxia on the testis: insights from a single-cell RNA sequencing analysis., PMID:38033870
GPR37 expression as a prognostic marker in gliomas: a bioinformatics-based analysis., PMID:37837549
GPR37 promotes colorectal cancer liver metastases by enhancing the glycolysis and histone lactylation via Hippo pathway., PMID:37749229
Activation of PI3K/Akt pathway by G protein-coupled receptor 37 promotes resistance to cisplatin-induced apoptosis in non-small cell lung cancer., PMID:37732632
Orphan G Protein-Coupled Receptor GPR37 as an Emerging Therapeutic Target., PMID:37676000
Towards the convergent therapeutic potential of G protein-coupled receptors in autism spectrum disorders., PMID:37574491
Efferocytes release extracellular vesicles to resolve inflammation and tissue injury via prosaposin-GPR37 signaling., PMID:37436891
L-DOPA Receptor GPR143 Functionally Couples with Adrenergic α1B Receptor at the Second Transmembrane Interface., PMID:37394637
Expression patterns of prosaposin and its receptors, G protein-coupled receptor (GPR) 37 and GPR37L1, in the mouse olfactory organ., PMID:37075680
GPR37 and Related Receptors: Disease Regulation., PMID:37047695
Coupling between GPR143 and dopamine D2 receptor is required for selective potentiation of dopamine D2 receptor function by L-3,4-dihydroxyphenylalanine in the dorsal striatum., PMID:36807226
Expression patterns of prosaposin and its receptors, G protein-coupled receptor (GPR) 37 and GPR37L1 mRNAs, in the chick inner ear., PMID:36750499
Expression of prosaposin and its G protein-coupled receptor (GPR) 37 in mouse cochlear and vestibular nuclei., PMID:36696997
Inflammation and Infection in Pain and the Role of GPR37., PMID:36430912
Impaired Aversive Memory Formation in GPR37L1KO Mice., PMID:36430766
Chlorogenic acid enhances alveolar macrophages phagocytosis in acute respiratory distress syndrome by activating G protein-coupled receptor 37 (GPR 37)., PMID:36194973
Identification of prognosis-related hub genes of ovarian cancer through bioinformatics analyses and experimental verification., PMID:36086731
GPR37 promotes cancer growth by binding to CDK6 and represents a new theranostic target in lung adenocarcinoma., PMID:35934193
Spatiotemporal Dynamics of the Molecular Expression Pattern and Intercellular Interactions in the Glial Scar Response to Spinal Cord Injury., PMID:35788904
GPR37 Receptors and Megalencephalic Leukoencephalopathy with Subcortical Cysts., PMID:35628339
Osteocalcin Alleviates Lipopolysaccharide-Induced Acute Inflammation via Activation of GPR37 in Macrophages., PMID:35625743
Mouse Mutants of Gpr37 and Gpr37l1 Receptor Genes: Disease Modeling Applications., PMID:35457105
Emerging Roles for the Orphan GPCRs, GPR37 and GPR37 L1, in Stroke Pathophysiology., PMID:35409385
Multipathway In Vitro Pharmacological Characterization of Specialized Proresolving G Protein-Coupled Receptors., PMID:35125345
Comparative analysis of protein-protein interaction networks in metastatic breast cancer., PMID:35045088
Proteomic profiling reveals antitumor effects of RT2 peptide on a human colon carcinoma xenograft mouse model., PMID:35032485
The Effect of Early Life Stress on Emotional Behaviors in GPR37KO Mice., PMID:35008836
GM1 Is Cytoprotective in GPR37-Expressing Cells and Downregulates Signaling., PMID:34884663
Cytosolic GPR37, but not GPR37L1, multimerization and its reversal by Parkin: A live cell imaging study., PMID:34822195
Osteocalcin attenuates oligodendrocyte differentiation and myelination via GPR37 signaling in the mouse brain., PMID:34678058
For research use only. Not for human or drug use.
