Catalog No.
YHK90901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu22-Glu72
Predicted molecular weight
34.26 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y605
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MORF4 family-associated protein 1, PGR1, Protein associated with MRG of 14 kDa, PAM14, MRFAP1, Protein PGR1
FBXW8-dependent degradation of MRFAP1 in anaphase controls mitotic cell death. PMID: 29228602
MRFAP1 plays a protective role in neddylation inhibitor MLN4924-mediated gastric cancer cell death. PMID: 30556867
Characterization of MRFAP1 turnover and interactions downstream of the NEDD8 pathway. PMID: 22038470
Characterization of native protein complexes and protein isoform variation using size-fractionation-based quantitative proteomics. PMID: 24043423
Selection of new appropriate reference genes for RT-qPCR analysis via transcriptome sequencing of cynomolgus monkeys (Macaca fascicularis). PMID: 23613744
Quantitative proteomic analysis of cellular protein modulation upon inhibition of the NEDD8-activating enzyme by MLN4924. PMID: 21873567
A viral vaccine encoding prostate-specific antigen induces antigen spreading to a common set of self-proteins in prostate cancer patients. PMID: 20562209
Interaction of Sedlin with PAM14. PMID: 20108251
Involvement of single nucleotide polymorphisms in ovarian poor response. PMID: 34050449
MRG15 activates the B-myb promoter through formation of a nuclear complex with the retinoblastoma protein and the novel protein PAM14. PMID: 11500496
PAM14, a novel MRG- and Rb-associated protein, is not required for development and T-cell function in mice. PMID: 15367658
Prognostic DNA methylation markers for hormone receptor breast cancer: a systematic review. PMID: 32005275
NRIP1 is activated by C-JUN/C-FOS and activates the expression of PGR, ESR1 and CCND1 in luminal A breast cancer. PMID: 34707101
Human prostaglandin reductase 1 (PGR1): Substrate specificity, inhibitor analysis and site-directed mutagenesis. PMID: 25619643
Race, Ethnicity, and Clinical Outcomes in Hormone Receptor-Positive, HER2-Negative, Node-Negative Breast Cancer in the Randomized TAILORx Trial. PMID: 32986828
Contribution of PGR genetic polymorphisms to the pathogenesis of endometrial cancer: A meta-analysis. PMID: 26881523
PGR and PTX3 gene expression in cumulus cells from obese and normal weighting women after administration of long-acting recombinant follicle-stimulating hormone for controlled ovarian stimulation. PMID: 30607593
Integrative analysis of miRNA and gene expression reveals regulatory networks in tamoxifen-resistant breast cancer. PMID: 27528030
Five polymorphisms and breast cancer risk: results from the Breast Cancer Association Consortium. PMID: 20381444
Polymorphisms in genes of the steroid hormone biosynthesis and metabolism pathways and endometrial cancer risk. PMID: 19861523
DNA hypermethylation of ESR1 and PGR in breast cancer: pathologic and epidemiologic associations. PMID: 17553165
Identification of novel androgen receptor target genes in prostate cancer. PMID: 16407074
Multipurpose MRG domain involved in cell senescence and proliferation exhibits structural homology to a DNA-interacting domain. PMID: 28490348
An international reproducibility study validating quantitative determination of ERBB2, ESR1, PGR, and MKI67 mRNA in breast cancer using MammaTyper®. PMID: 27230828
Identifications of novel mechanisms in breast cancer cells involving duct-like multicellular spheroid formation after exposure to the Random Positioning Machine. PMID: 24815444
ESR1 and PGR gene promoter methylation and correlations with estrogen and progesterone receptors in ductal and lobular breast cancer. PMID: 23765422
Hypoxia-dependent mRNA expression pattern of splicing factor YT521 and its impact on oncological important target gene expression. PMID: 19739075
Polymorphisms in genes of the steroid receptor superfamily modify postmenopausal breast cancer risk associated with menopausal hormone therapy. PMID: 21185374
Persistent and non-persistent changes in gene expression result from long-term estrogen exposure of MCF-7 breast cancer cells. PMID: 17008723
The MRG domain of human MRG15 uses a shallow hydrophobic pocket to interact with the N-terminal region of PAM14. PMID: 19551860
Common germline polymorphisms in COMT, CYP19A1, ESR1, PGR, SULT1E1 and STS and survival after a diagnosis of breast cancer. PMID: 18841818
For research use only. Not for human or drug use.
