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Recombinant Human MCC Protein, N-GST & C-His

Catalog #:   YHD58701 Specific References (93) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: P23508
Protein length: Leu224-Ser294
Overview

Catalog No.

YHD58701

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Leu224-Ser294

Predicted molecular weight

36.53 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

P23508

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

MCC, Protein MCC, Colorectal mutant cancer protein

Data Image
  • SDS-PAGE
    SDS PAGE for Recombinant Human MCC protein
References

MCC is a centrosomal protein that relocalizes to non-centrosomal apical sites during intestinal cell differentiation. PMID: 36217793

MCC and PSC, the putative protein import channels of mitochondria. PMID: 11768761

Role of MCC/Eisosome in Fungal Lipid Homeostasis. PMID: 31349700

MCC' protein interacts with E-cadherin and β-catenin strengthening cell-cell adhesion of HCT116 colon cancer cells. PMID: 29035389

MCC, a cytoplasmic protein that blocks cell cycle progression from the G0/G1 to S phase. PMID: 8626604

CDC20 assists its catalytic incorporation in the mitotic checkpoint complex. PMID: 33384373

MCC, a new interacting protein for Scrib, is required for cell migration in epithelial cells. PMID: 19555689

Ready-to-drink protein beverages: Effects of milk protein concentration and type on flavor. PMID: 34304878

Plasma Membrane MCC/Eisosome Domains Promote Stress Resistance in Fungi. PMID: 32938742

Protein Crystallization Identification via Fuzzy Model on Linear Neighborhood Representation. PMID: 31751248

DCSE:Double-Channel-Siamese-Ensemble model for protein protein interaction prediction. PMID: 35922751

Prion-like characteristics of the bacterial protein Microcin E492. PMID: 28361921

Acid gelation properties of fibrillated model milk protein concentrate dispersions. PMID: 35465995

Delta-Like Protein 3 Expression and Targeting in Merkel Cell Carcinoma. PMID: 32372416

Kinetochore-catalyzed MCC formation: A structural perspective. PMID: 36518060

The Mad2-Binding Protein p31comet as a Potential Target for Human Cancer Therapy. PMID: 33511944

Sequence-Based Prediction of Transmembrane Protein Crystallization Propensity. PMID: 34143353

Fungal plasma membrane domains. PMID: 31504467

The PDZ domain protein Mcc is a novel effector of non-canonical Wnt signaling during convergence and extension in zebrafish. PMID: 25183869

Microdomain Protein Nce102 Is a Local Sensor of Plasma Membrane Sphingolipid Balance. PMID: 35758748

Role of ubiquitin-protein ligase UBR5 in the disassembly of mitotic checkpoint complexes. PMID: 35217622

Use of micellar casein concentrate and milk protein concentrate treated with transglutaminase in imitation cheese products-Melt and stretch properties. PMID: 36055846

MCC inhibits beta-catenin transcriptional activity by sequestering DBC1 in the cytoplasm. PMID: 24824780

Process development for a novel milk protein concentrate with whey proteins as fibrils. PMID: 33485682

Tim23, a protein import component of the mitochondrial inner membrane, is required for normal activity of the multiple conductance channel, MCC. PMID: 9128249

Improving Protein Gamma-Turn Prediction Using Inception Capsule Networks. PMID: 30356073

Use of micellar casein concentrate and milk protein concentrate treated with transglutaminase in imitation cheese products-Unmelted texture. PMID: 36055836

Transcriptional regulation of multiciliated cell differentiation. PMID: 32362381

CrystalM: A Multi-View Fusion Approach for Protein Crystallization Prediction. PMID: 31027046

Computational Modeling of Protein Stability: Quantitative Analysis Reveals Solutions to Pervasive Problems. PMID: 32375024

Structural protein descriptors in 1-dimension and their sequence-based predictions. PMID: 21787299

Prediction of Protein-Protein Interactions with Local Weight-Sharing Mechanism in Deep Learning. PMID: 32626745

Insight into Tor2, a budding yeast microdomain protein. PMID: 24629393

Deep protein representations enable recombinant protein expression prediction. PMID: 34775287

Mutated in colorectal cancer protein modulates the NFκB pathway. PMID: 22213290

Developing Computational Model to Predict Protein-Protein Interaction Sites Based on the XGBoost Algorithm. PMID: 32218345

Tart cherry concentrate does not enhance muscle protein synthesis response to exercise and protein in healthy older men. PMID: 29890270

Plant produced endotoxin binding recombinant proteins effectively remove endotoxins from protein samples. PMID: 36180579

Transient protein-protein interface prediction: datasets, features, algorithms, and the RAD-T predictor. PMID: 24661439

Huntingtin-interacting protein 1: a Merkel cell carcinoma marker that interacts with c-Kit. PMID: 21697888

Identification of Protein-Ligand Binding Sites by Sequence Information and Ensemble Classifier. PMID: 29125297

The PDZ-binding motif of MCC is phosphorylated at position -1 and controls lamellipodia formation in colon epithelial cells. PMID: 22480440

Structure-based prediction of protein- peptide binding regions using Random Forest. PMID: 29028926

Interaction of MCC2, a novel homologue of MCC tumor suppressor, with PDZ-domain Protein AIE-75. PMID: 11311560

Coordinated regulation of TORC2 signaling by MCC/eisosome-associated proteins, Pil1 and tetraspan membrane proteins during the stress response. PMID: 35383382

Effects of micellar casein concentrate purity and milk fat on sulfur/eggy flavor in ultrapasteurized milk-based beverages. PMID: 35525620

Sequence-based prediction of protein-binding sites in DNA: comparative study of two SVM models. PMID: 25113160

Enhancing protein-vitamin binding residues prediction by multiple heterogeneous subspace SVMs ensemble. PMID: 25189131

DeepCrystal: a deep learning framework for sequence-based protein crystallization prediction. PMID: 30462171

MCC-555-induced NAG-1 expression is mediated in part by KLF4. PMID: 20385121

Steric exclusion and protein conformation determine the localization of plasma membrane transporters. PMID: 29402931

Expression of proton-sensing G-protein-coupled receptors in selected skin tumors. PMID: 30339292

The Candida albicans Sur7 protein is needed for proper synthesis of the fibrillar component of the cell wall that confers strength. PMID: 21115741

Frequent inactivation of MCC/CTNNBIP1 and overexpression of phospho-beta-catenin(Y654) are associated with breast carcinoma: Clinical and prognostic significance. PMID: 27208794

A protein succinylation sites prediction method based on the hybrid architecture of LSTM network and CNN. PMID: 35191361

Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment. PMID: 23975762

Structural analysis of phosphorylation-associated interactions of human MCC with Scribble PDZ domains. PMID: 31317644

Prediction of FAD interacting residues in a protein from its primary sequence using evolutionary information. PMID: 20122222

Stable MCC binding to the APC/C is required for a functional spindle assembly checkpoint. PMID: 24464857

Predicting protein solubility with a hybrid approach by pseudo amino acid composition. PMID: 20937038

Functional reciprocity of proteins involved in mitosis and endocytosis. PMID: 33300206

Recognition of Protein Pupylation Sites by Adopting Resampling Approach. PMID: 30486421

Entropy of Proteins Using Multiscale Cell Correlation. PMID: 32955869

Prediction of protein-protein binding site by using core interface residue and support vector machine. PMID: 19102736

Encapsulation of concentrated protein into erythrocyte porated by continuous-wave ultrasound. PMID: 18597920

Predict and Analyze Protein Glycation Sites with the mRMR and IFS Methods. PMID: 25961025

Computational prediction of protein-protein interactions in Leishmania predicted proteomes. PMID: 23251492

Association of VAMP5 and MCC genetic polymorphisms with increased risk of Hirschsprung disease susceptibility in Southern Chinese children. PMID: 29695640

Effect of protein release rates from tablet formulations on the immune response after sublingual immunization. PMID: 22959953

Protein function annotation from sequence: prediction of residues interacting with RNA. PMID: 19389733

Improved Prediction of Protein-Protein Interaction Mapping on Homo Sapiens by Using Amino Acid Sequence Features in a Supervised Learning Framework. PMID: 32520672

A MOTIF-BASED METHOD FOR PREDICTING INTERFACIAL RESIDUES IN BOTH THE RNA AND PROTEIN COMPONENTS OF PROTEIN-RNA COMPLEXES. PMID: 26776208

A new immunohistochemical marker, insulinoma-associated protein 1 (INSM1), for Merkel cell carcinoma: Evaluation of 24 cases. PMID: 31031215

A simple approach for predicting protein-protein interactions. PMID: 20887258

Mitotic phosphatase activity is required for MCC maintenance during the spindle checkpoint. PMID: 26652909

Discovery of cell compartment specific protein-protein interactions using affinity purification combined with tandem mass spectrometry. PMID: 23157168

Closed MAD2 (C-MAD2) is selectively incorporated into the mitotic checkpoint complex (MCC). PMID: 22037211

Milademetan is a highly potent MDM2 inhibitor in Merkel cell carcinoma. PMID: 35801592

Fungal membrane organization: the eisosome concept. PMID: 25002088

PredHydroxy: computational prediction of protein hydroxylation site locations based on the primary structure. PMID: 25534958

Microcin C: biosynthesis and mechanisms of bacterial resistance. PMID: 22324995

Quantification of Golgi Protein Mislocalization to the Budding Yeast Vacuole. PMID: 36512206

Textural performance of crosslinked or reduced-calcium milk protein ingredients in model high-protein nutrition bars. PMID: 27236767

Molecular-Charge-Contact-Based Ion-Sensitive Field-Effect Transistor Sensor in Microfluidic System for Protein Sensing. PMID: 31382441

Histidine-Triad Hydrolases Provide Resistance to Peptide-Nucleotide Antibiotics. PMID: 32265328

Fission Yeast Apc15 Stabilizes MCC-Cdc20-APC/C Complexes, Ensuring Efficient Cdc20 Ubiquitination and Checkpoint Arrest. PMID: 28366744

NAGbinder: An approach for identifying N-acetylglucosamine interacting residues of a protein from its primary sequence. PMID: 31654438

Genomic evidence suggests that cutaneous neuroendocrine carcinomas can arise from squamous dysplastic precursors. PMID: 34593967

The Scf/Kit pathway implements self-organized epithelial patterning. PMID: 33756121

Escape from the checkpoint: Nek2A binds a unique conformation of the APC/C-MCC complex. PMID: 32431068

Impact of carboxymethyl cellulose (CMC) and microcrystalline cellulose (MCC) on functional characteristics of emulsified sausages. PMID: 23036941

Flavor and stability of milk proteins. PMID: 27060829

APC15 mediates CDC20 autoubiquitylation by APC/C(MCC) and disassembly of the mitotic checkpoint complex. PMID: 23007861

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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Recombinant Human MCC Protein, N-GST & C-His [YHD58701]
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