Serum Amyloid A (SAA) Proteins. PMID: 32189310
Cancer-associated adipocytes promote pancreatic cancer progression through SAA1 expression. PMID: 32535957
Secondary, AA, Amyloidosis. PMID: 30274625
Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease. PMID: 31866067
Serum amyloid A1 exacerbates hepatic steatosis via TLR4-mediated NF-κB signaling pathway. PMID: 35247611
Serum amyloid A1 (SAA1) protein in human colostrum. PMID: 29511620
Arecoline induces epithelial-mesenchymal transformation and promotes metastasis of oral cancer by SAA1 expression. PMID: 33626219
Inhibition of Fatty Acid-Binding Protein 4 Attenuated Kidney Fibrosis by Mediating Macrophage-to-Myofibroblast Transition. PMID: 33101287
Serum amyloid A promotes LPS clearance and suppresses LPS-induced inflammation and tissue injury. PMID: 30126923
SAA1 regulates pro-labour mediators in term labour by activating YAP pathway. PMID: 33719002
Serum level of serum amyloid A1 protein in patients with acne vulgaris. PMID: 34449969
Cell-to-cell transfer of SAA1 protein in a cell culture model of systemic AA amyloidosis. PMID: 28361953
Enhancement of cortisol-induced SAA1 transcription by SAA1 in the human amnion. PMID: 30817315
De novo Synthesis of SAA1 in the Placenta Participates in Parturition. PMID: 32582166
Serum amyloid A primes microglia for ATP-dependent interleukin-1β release. PMID: 29803222
SAA1 gene polymorphisms in osteoporosis patients. PMID: 30737305
SAA1 is transcriptionally activated by STAT3 and accelerates renal interstitial fibrosis by inducing endoplasmic reticulum stress. PMID: 34597680
Identification of a Signaling Mechanism by Which the Microbiome Regulates Th17 Cell-Mediated Depressive-Like Behaviors in Mice. PMID: 32731813
Elevated SAA1 promotes the development of insulin resistance in ovarian granulosa cells in polycystic ovary syndrome. PMID: 34980155
High-resolution serum proteome trajectories in COVID-19 reveal patient-specific seroconversion. PMID: 34232570
SAA1 increases NOX4/ROS production to promote LPS-induced inflammation in vascular smooth muscle cells through activating p38MAPK/NF-κB pathway. PMID: 31216990
CRP and SAA1 Haplotypes Are Associated with Both C-Reactive Protein and Serum Amyloid A Levels: Role of Suppression Effects. PMID: 27313400
Identification of SAA1 as a prognostic biomarker associated with immune infiltration in glioblastoma. PMID: 35574600
Serum Amyloid A1 (SAA1) Revisited: Restricted Leukocyte-Activating Properties of Homogeneous SAA1. PMID: 32477346
SAA1 is upregulated in gastric cancer-associated fibroblasts possibly by its enhancer activation. PMID: 33284950
Dysregulation of SAA1, TUBA8 and Monocytes Are Key Factors in Ankylosing Spondylitis With Femoral Head Necrosis. PMID: 35126370
SAA1 polymorphisms are associated with variation in antiangiogenic and tumor-suppressive activities in nasopharyngeal carcinoma. PMID: 24608426
Expression of mouse apolipoprotein SAA1.1 in CE/J mice: isoform-specific effects on amyloidogenesis. PMID: 11140693
Differential protein expression in patients with urosepsis. PMID: 30340979
SAA1 deficiency alleviates cardiac remodeling by inhibiting NF-κB/p38/JNK and TGFβ/Smad pathways. PMID: 37022639
Expression of SAA1, SAA2 and SAA4 genes in human primary monocytes and monocyte-derived macrophages. PMID: 31100086
Adipocyte-Derived Serum Amyloid A Promotes Angiotensin II-Induced Abdominal Aortic Aneurysms in Obese C57BL/6J Mice. PMID: 35344382
Hepatocytes derived increased SAA1 promotes intrahepatic platelet aggregation and aggravates liver inflammation in NAFLD. PMID: 33813276
Investigating the pernicious effects of heparan sulfate in serum amyloid A1 protein aggregation: a structural bioinformatics approach. PMID: 33050843
A mutation in the SAA1 promoter causes hereditary amyloid A amyloidosis. PMID: 34560138
Involvement of STAT3 in the synergistic induction of 11β-HSD1 by SAA1 and cortisol in human amnion fibroblasts. PMID: 31131948
Silencing of SAA1 inhibits palmitate- or high-fat diet induced insulin resistance through suppression of the NF-κB pathway. PMID: 31060494
Mouse Bone Marrow Mesenchymal Stem Cells Inhibit Sepsis-Induced Lung Injury in Mice via Exosomal SAA1. PMID: 36173129
Diversity and complexity of the mouse Saa1 and Saa2 genes. PMID: 24521869
Serum amyloid A1: Structure, function and gene polymorphism. PMID: 26945629
Serum amyloid A and atherosclerosis. PMID: 27579547
Serum SAA1 and APOE are novel indicators for human cytomegalovirus infection. PMID: 29042594
Cellular mechanism of fibril formation from serum amyloid A1 protein. PMID: 28637682
Quantification of SAA1 and SAA2 in lung cancer plasma using the isotype-specific PRM assays. PMID: 26177823
COOH-terminal SAA1 peptides fail to induce chemokines but synergize with CXCL8 and CCL3 to recruit leukocytes via FPR2. PMID: 29371208
Signal peptide stabilizes folding and inhibits misfolding of serum amyloid A. PMID: 36309973
AA amyloidosis-resistant CE/J mice have Saa1 and Saa2 genes that encode an identical SAA isoform. PMID: 24228751
Measurement of serum amyloid A1 (SAA1), a major isotype of acute phase SAA. PMID: 16375587
Both murine SAA1 and SAA2 yield AA amyloid in alveolar hydatid cyst-infected mice. PMID: 8633197
SAA1 alleles as risk factors in reactive systemic AA amyloidosis. PMID: 10036584
Docosahexaenoic acid enhances hepatic serum amyloid A expression via protein kinase A-dependent mechanism. PMID: 19755416
SAA1 Has Potential as a Prognostic Biomarker Correlated with Cell Proliferation, Migration, and an Indicator for Immune Infiltration of Tumor Microenvironment in Clear Cell Renal Cell Carcinoma. PMID: 37108666
The contribution of SAA1 polymorphisms to Familial Mediterranean fever susceptibility in the Japanese population. PMID: 23437051
SAA1 gene variants and childhood obesity in China. PMID: 24171731
Effects of serum amyloid protein A on influenza A virus replication and viral interactions with neutrophils. PMID: 33205458
Protein profiling of isolated uterine AA amyloidosis causing fetal death in goats. PMID: 25422367
Post-translational modification of amyloid a protein in patients with AA amyloidosis. PMID: 34787027
Influence of genotypes at SAA1 and SAA2 loci on the development and the length of latent period of secondary AA-amyloidosis in patients with rheumatoid arthritis. PMID: 10543406
Serum Proteomic Analysis Identifies SAA1, FGA, SAP, and CETP as New Biomarkers for Eosinophilic Granulomatosis With Polyangiitis. PMID: 35757752
SAA1 alpha/alpha alleles in Behçet's disease related amyloidosis. PMID: 17039260
Editorial comment on: inflammatory protein serum amyloid A1 marks a subset of conventional renal cell carcinomas with fatal outcome. PMID: 19747759
Influence of Serum Amyloid A (SAA1) and SAA2 gene polymorphisms on renal amyloidosis, and on SAA/C-reactive protein values in patients with familial mediterranean fever in the Turkish population. PMID: 15170927
SAA1 is over-expressed in plasma of non small cell lung cancer patients with poor outcome after treatment with epidermal growth factor receptor tyrosine-kinase inhibitors. PMID: 22771314
SAA1 genetic polymorphisms are associated with plasma glucose concentration in non-diabetic subjects. PMID: 23940069
Serum amyloid A3 is a high density lipoprotein-associated acute-phase protein. PMID: 29247043
Inflammatory protein serum amyloid A1 marks a subset of conventional renal cell carcinomas with fatal outcome. PMID: 19747761
Revisiting misfolding propensity of serum amyloid A1: Special focus on the signal peptide region. PMID: 35664543
AA amyloidosis - Benefits and prospects of IL-6 inhibitors. PMID: 30132351
Associations of genetic polymorphisms of SAA1 with cerebral infarction. PMID: 23987125
Time-resolved fluorescent immunoassay-based combined detection of procalcitonin, C-reactive protein, heparin binding protein, and serum amyloid A1 to improve the diagnostic accuracy of early infection. PMID: 30338547
Discovery of Potential Serum Protein Biomarkers in Ankylosing Spondylitis Using Tandem Mass Tag-Based Quantitative Proteomics. PMID: 31917576
iTRAQ-based proteomic analysis of differentially expressed proteins in sera of seronegative and seropositive rheumatoid arthritis patients. PMID: 34812532
Identification of Genetic Associations and Functional Polymorphisms of SAA1 Gene Affecting Milk Production Traits in Dairy Cattle. PMID: 27610623
Serum amyloid A1 (SAA1) gene polymorphisms in Japanese patients with adult-onset Still's disease. PMID: 30544414
Chitinase-3-Like Protein 1, Serum Amyloid A1, C-Reactive Protein, and Procalcitonin Are Promising Biomarkers for Intracranial Severity Assessment of Traumatic Brain Injury: Relationship with Glasgow Coma Scale and Computed Tomography Volumetry. PMID: 31606503
The plasma peptides of sepsis. PMID: 32636717
FABP4 in Paneth cells regulates antimicrobial protein expression to reprogram gut microbiota. PMID: 36519446
Associations of SAA1 gene polymorphism with lipid lelvels and osteoporosis in Chinese women. PMID: 23522429
Significance of SAA1.3 allele genotype in Japanese patients with amyloidosis secondary to rheumatoid arthritis. PMID: 16219644
HDL proteome remodeling associates with COVID-19 severity. PMID: 34802985
Characterization of amyloid A protein in human secondary amyloidosis: the predominant deposition of serum amyloid A1. PMID: 7827140
Differential expression of serum amyloid A1 and A3 in bovine epithelia. PMID: 32378645
Rs12218 In SAA1 gene was associated with serum lipid levels. PMID: 23898911
Current perspectives on familial Mediterranean fever. PMID: 19339884
A novel polymorphism of human serum amyloid A protein, SAA1 gamma, is characterized by alanines at both residues 52 and 57. PMID: 8512321
Clinical strategies for amyloid A amyloidosis secondary to rheumatoid arthritis. PMID: 18369528
C-reactive protein and serum amyloid a overexpression in lung tissues of chronic obstructive pulmonary disease patients: a case-control study. PMID: 23801879
A novel allelic variant of serum amyloid A, SAA1 gamma: genomic evidence, evolution, frequency, and implication as a risk factor for reactive systemic AA-amyloidosis. PMID: 7655463
Serum amyloid A3 is pro-atherogenic. PMID: 29175652
Expression of mouse acute-phase (SAA1.1) and constitutive (SAA4) serum amyloid A isotypes: influence on lipoprotein profiles. PMID: 10845870
Genetically determined recurrent fevers. PMID: 11544000
Human SAA1-derived amyloid deposition in cell culture: a consistent model utilizing human peripheral blood mononuclear cells and serum-free medium. PMID: 23461622
Multi-walled carbon nanotube-physicochemical properties predict the systemic acute phase response following pulmonary exposure in mice. PMID: 28380028
Human serum amyloid A protein. Complete amino acid sequence of a new variant. PMID: 1546977
Robust Acute Pancreatitis Identification and Diagnosis: RAPIDx. PMID: 36988967
MFGE8, ALB, APOB, APOE, SAA1, A2M, and C3 as Novel Biomarkers for Stress Cardiomyopathy. PMID: 32695227
Tissue-specific regulation of the human acute-phase serum amyloid A genes, SAA1 and SAA2, by glucocorticoids in hepatic and epithelial cells. PMID: 12938239
Serum amyloid A1 mediates myotube atrophy via Toll-like receptors. PMID: 31441598
SAA1 Promotes Ulcerative Colitis and Activating Colonic TLR4/NF-κB/NLRP3 Signaling Pathway., PMID:40526227
Effect of a Laparoscopic Donor Nephrectomy in Healthy Living Kidney Donors on the Acute Phase Response Using Either Propofol or Sevoflurane Anesthesia., PMID:40508008
SAA1 deletion ameliorates cardiac injury after myocardial infarction by promoting macrophage transformation to reparative subtype., PMID:40460795
Identification of EPHB4 as a potential causal gene and therapeutic target for endometriosis using Mendelian randomization., PMID:40450304
Characterization of immune features and discovery of potential biomarkers for ankylosing spondylitis using deep plasma proteomics., PMID:40436140
New biomarkers of Kawasaki disease identified by gingival crevicular fluid proteomics., PMID:40421421
Supplementing with Vitamin D during Pregnancy Reduces Inflammation and Prevents Autism-Related Behaviors in Offspring Caused by Maternal Immune Activation., PMID:40383635
Target complement factor H / serum amyloid a signaling in trichloroethylene-induced immune kidney injury., PMID:40373713
Quercetin-doped sol-gel coatings on titanium implants: a promising approach for enhanced immune response and cell adhesion., PMID:40371955
Differential expression reveals inflammatory response and oxidative stress genes in dentin caries., PMID:40305968
SAA1 Protein: A Potential Biomarker for Acute Myeloid Leukemia., PMID:40299483
The role of adherent-to-suspension transition factors in clear cell renal cell carcinoma progression: a comprehensive analysis., PMID:40253446
The aggregation tendencies of the signal peptide regions of prone and not prone to aggregate proteins., PMID:40212812
Newly-diagnosed rheumatoid arthritis patients have elevated levels of plasma extracellular vesicles with protein cargo altered towards inflammatory processes., PMID:40185859
Early changes in inflammation-related proteins in the cerebrospinal fluid and plasma of patients with aneurysmal subarachnoid hemorrhage., PMID:40180229
Discovering potential therapeutic targets in glioblastoma multiforme using a multi-omics approach., PMID:40168776
Prediction of influenza virus infection based on deep learning and peripheral blood proteomics: A diagnostic study., PMID:40158620
Peptidomics characteristics of pediatric sepsis., PMID:40108253
TAF7 directly targets SAA1 to enhance triple-negative breast cancer metastasis via phosphorylating E-cadherin and N-cadherin., PMID:40083715
Functional Interactions Between Recombinant Serum Amyloid A1 (SAA1) and Chemokines in Leukocyte Recruitment., PMID:40076881
Balancing inflammation: the specific roles of serum amyloid A proteins in sterile and infectious diseases., PMID:40061939
SAA1 as a key mediator of immune inflammatory pathways in fungal keratitis through FOXO3a phosphorylation regulation., PMID:40020519
Serum Amyloid A1 Mediates Paclitaxel Resistance via MD2-Dependent Pathways in Triple-Negative Breast Cancer., PMID:40012323
Integrated Clinomics and Molecular Dynamics Simulation Approaches Reveal the SAA1.1 Allele as a Biomarker in Alkaptonuria Disease Severity., PMID:40001497
Delayed hepatic response and impaired cytokine dynamics in aged mice following burn injury: Implications for elderly patient care., PMID:39992944
Novel plasma biomarkers of amyloid plaque pathology and cortical thickness: Evaluation of the NULISA targeted proteomic platform in an ethnically diverse cohort., PMID:39989429
Serum Amyloid A Binding to Glycosaminoglycans is Synergistic with Amyloid Formation: Therapeutic Targeting in the Inflammation-linked Amyloidosis., PMID:39954777
Spatial multi-omics characterizes GPR35-relevant lipid metabolism signatures across liver zonation in MASLD., PMID:39873004
Single-Cell RNA-Seq Uncovers Cellular Heterogeneity from Deep Fascia in Necrotizing Fasciitis Patients., PMID:39867946
Identification and characterization of spontaneous AA amyloidosis in CD-1 mice used in toxicity studies: implications of SAA1 and SAA2 copy number variations., PMID:39839724
Identification of hub programmed cell death-related genes and immune infiltration in Crohn's disease using bioinformatics., PMID:39744064
PPARα-ERRα crosstalk mitigates metabolic dysfunction-associated steatotic liver disease progression., PMID:39743041
Plasma acute phase proteins as potential predictors of intra-amniotic inflammation and infection in preterm premature rupture of membranes., PMID:39711480
Using Multi-Omics Analysis to Explore Diagnostic Tool and Optimize Drug Therapy Selection for Patients with Glioma Based on Cross-Talk Gene Signature., PMID:39574472
Apocrine Gland Damage and the Release of Specific Keratins in Early Stage Indicate the Crucial Involvement of Apocrine Glands in Hidradenitis Suppurativa., PMID:39547394
The Clinical and Molecular Response of Pyoderma Gangrenosum to IL-23 Blockade: Result from a Proof-of-Concept Open-Label Clinical Trial., PMID:39547392
Comparative Analysis of Plasma Protein Dynamics in Women with ST-Elevation Myocardial Infarction and Takotsubo Syndrome., PMID:39513871
Transcriptomic analysis of melanoma cells reveals an association of α-synuclein with regulation of the inflammatory response., PMID:39511366
Nature of recombinant human serum amyloid A1 in Escherichia coli and its preferable approach for purification., PMID:39505093
Exosomal miR-199a-3p Secreted From Cancer-Associated Adipocytes Promotes Pancreatic Cancer Progression., PMID:39431622
FPR1 signaling aberrantly regulates S100A8/A9 production by CD14+FCN1hi macrophages and aggravates pulmonary pathology in severe COVID-19., PMID:39402337
Extracellular vesicles bearing serum amyloid A1 exacerbate neuroinflammation after intracerebral haemorrhage., PMID:39357895
Inflammation and Tumor Progression: The Differential Impact of SAA in Breast Cancer Models., PMID:39336082
Unveiling novel serum biomarkers in intrahepatic cholangiocarcinoma: a pilot proteomic exploration., PMID:39286634
Serum amyloid A1 induced dysfunction of airway macrophages via CD36 pathway in allergic airway inflammation., PMID:39244902
Role of SAA1 in Endometrial Extracellular Matrix Remodeling in Polycystic Ovary Syndrome: Implication for Pregnancy Loss., PMID:39210610
Plasma proteomics implicate glutamic oxaloacetic transaminases as potential markers for acute myocardial infarction., PMID:39173902
The Potential of Eight Plasma Proteins as Biomarkers in Redefining Leptospirosis Diagnosis., PMID:39150348
Key charged residues influence the amyloidogenic propensity of the helix-1 region of serum amyloid A., PMID:39117048
Characterization of Inflammation/Immune-, Acute Phase-, Extracellular Matrix-, Adhesion-, and Serine Protease-Related Proteins in the Amniotic Fluid of Women With Early Preterm Prelabor Rupture of Membranes., PMID:39113666
For research use only. Not for human or drug use.
