Bld10p/Cep135 determines the number of triplets in the centriole independently of the cartwheel. PMID: 36093892
CEP135 isoform dysregulation promotes centrosome amplification in breast cancer cells. PMID: 30811267
Drosophila Cep135/Bld10 maintains proper centriole structure but is dispensable for cartwheel formation. PMID: 22976301
Mutation in CEP135 causing primary microcephaly and subcortical heterotopia. PMID: 32643282
CEP135 associated primary microcephaly-A rare presentation in early second trimester. PMID: 33933664
Genomic and phenotypic delineation of congenital microcephaly. PMID: 30214071
A Short CEP135 Splice Isoform Controls Centriole Duplication. PMID: 26412126
Mitotic Maturation Compensates for Premature Centrosome Splitting and PCM Loss in Human cep135 Knockout Cells. PMID: 35406752
Bld10/Cep135 stabilizes basal bodies to resist cilia-generated forces. PMID: 23115304
Abnormal centrosomal structure and duplication in Cep135-deficient vertebrate cells. PMID: 23864714
Human microcephaly protein CEP135 binds to hSAS-6 and CPAP, and is required for centriole assembly. PMID: 23511974
Interaction of Cep135 with a p50 dynactin subunit in mammalian centrosomes. PMID: 14983524
miR-26b Targets CEP135 Gene to Regulate Nasopharyngeal Carcinoma Proliferation and Migration by NF-κB Pathway. PMID: 36820950
The Human Centriolar Protein CEP135 Contains a Two-Stranded Coiled-Coil Domain Critical for Microtubule Binding. PMID: 27477386
BLD10/CEP135 is a microtubule-associated protein that controls the formation of the flagellum central microtubule pair. PMID: 22898782
Comprehensive review on the molecular genetics of autosomal recessive primary microcephaly (MCPH). PMID: 30086807
A novel function of CEP135 as a platform protein of C-NAP1 for its centriolar localization. PMID: 18851962
Characterization of Cep135, a novel coiled-coil centrosomal protein involved in microtubule organization in mammalian cells. PMID: 11781336
A truncating mutation of CEP135 causes primary microcephaly and disturbed centrosomal function. PMID: 22521416
A homozygous CEP135 mutation is associated with multiple morphological abnormalities of the sperm flagella (MMAF). PMID: 28866084
Cartwheel assembly. PMID: 25047612
The Association of CEP135 rs4865047 and NPY2R rs1902491 Single Nucleotide Polymorphisms (SNPs) with Rapid Progression of Proliferative Diabetic Retinopathy in Patients with Type 1 Diabetes Mellitus. PMID: 30531682
Filamentous polymers induced by overexpression of a novel centrosomal protein, Cep135. PMID: 10842375
Multisite phosphorylation of C-Nap1 releases it from Cep135 to trigger centrosome disjunction. PMID: 24695856
A novel splice site mutation in CEP135 is associated with primary microcephaly in a Pakistani family. PMID: 26657937
How the newborn centriole becomes a mother. PMID: 27223270
The centriolar protein Bld10/Cep135 is required to establish centrosome asymmetry in Drosophila neuroblasts. PMID: 24954048
An update of pathogenic variants in ASPM, WDR62, CDK5RAP2, STIL, CENPJ, and CEP135 underlying autosomal recessive primary microcephaly in 32 consanguineous families from Pakistan. PMID: 32677750
Superresolution characterization of core centriole architecture. PMID: 33533934
WDR8 is a centriolar satellite and centriole-associated protein that promotes ciliary vesicle docking during ciliogenesis. PMID: 26675238
High-confidence cancer patient stratification through multiomics investigation of DNA repair disorders. PMID: 36435816
Molecular genetics of human primary microcephaly: an overview. PMID: 25951892
Deficient adaptation to centrosome duplication defects in neural progenitors causes microcephaly and subcortical heterotopias. PMID: 34237032
CEP proteins: the knights of centrosome dynasty. PMID: 23456457
Conserved molecular interactions in centriole-to-centrosome conversion. PMID: 26595382
Basal body structure and composition in the apicomplexans Toxoplasma and Plasmodium. PMID: 26855772
Autosomal recessive primary microcephalies (MCPH). PMID: 24780602
Molecular evolutionary analysis of human primary microcephaly genes. PMID: 33941077
Stepwise evolution of the centriole-assembly pathway. PMID: 20392737
A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. PMID: 35442950
Primary Autosomal Recessive Microcephalies and Seckel Syndrome Spectrum Disorders – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY. PMID: 20301772
Homozygous mutations in DZIP1 can induce asthenoteratospermia with severe MMAF. PMID: 32051257
Plk4-induced centriole biogenesis in human cells. PMID: 17681131
The 3D architecture and molecular foundations of de novo centriole assembly via bicentrioles. PMID: 34433076
A method of quantifying centrosomes at the single-cell level in human normal and cancer tissue. PMID: 30699045
Drosophila Ana1 is required for centrosome assembly and centriole elongation. PMID: 27206860
Replication analysis for severe diabetic retinopathy. PMID: 22427569
Loss of Cep135 causes oligoasthenoteratozoospermia and male infertility in mice., PMID:40095067
Interactions of N- and C-terminal parts of Ana1 permitting centriole duplication but not elongation., PMID:39904373
Clinical genomics expands the link between erroneous cell division, primary microcephaly and intellectual disability., PMID:38795246
CP110 and CEP135 Localize Near the Proximal Centriolar Remnants of Mice Spermatozoa., PMID:38351906
Interactome Analysis Reveals a Link of the Novel ALMS1-CEP70 Complex to Centrosomal Clusters., PMID:38122899
Centrosomal Protein CEP135 Regulates the Migration and Angiogenesis of Endothelial Cells in a Microtubule-Dependent Manner., PMID:38062802
CP110 and CEP135 localize near the proximal and distal centrioles of cattle and human spermatozoa., PMID:37822686
A phylogenetic profiling approach identifies novel ciliogenesis genes in Drosophila and C. elegans., PMID:37317646
Investigation of enzalutamide, docetaxel, and cabazitaxel resistance in the castration resistant prostate cancer cell line C4 using genome-wide CRISPR/Cas9 screening., PMID:37270558
miR-26b Targets CEP135 Gene to Regulate Nasopharyngeal Carcinoma Proliferation and Migration by NF-κB Pathway., PMID:36820950
Research on the pathological mechanism of rectal adenocarcinoma based on DNA methylation., PMID:36705386
High-confidence cancer patient stratification through multiomics investigation of DNA repair disorders., PMID:36435816
Bld10p/Cep135 determines the number of triplets in the centriole independently of the cartwheel., PMID:36093892
Phylogenetic distribution and expression pattern analyses identified a divergent basal body assembly protein involved in land plant spermatogenesis., PMID:35842793
A modified TurboID approach identifies tissue-specific centriolar components in C. elegans., PMID:35442950
Mitotic Maturation Compensates for Premature Centrosome Splitting and PCM Loss in Human cep135 Knockout Cells., PMID:35406752
Genetic interaction between PLK1 and downstream MCPH proteins in the control of centrosome asymmetry and cell fate during neural progenitor division., PMID:35058575
Deficient adaptation to centrosome duplication defects in neural progenitors causes microcephaly and subcortical heterotopias., PMID:34237032
Triple deletion of TP53, PCNT, and CEP215 promotes centriole amplification in the M phase., PMID:34233584
Molecular evolutionary analysis of human primary microcephaly genes., PMID:33941077
CEP135 associated primary microcephaly-A rare presentation in early second trimester., PMID:33933664
Superresolution characterization of core centriole architecture., PMID:33533934
Investigating the Transition of Pre-Symptomatic to Symptomatic Huntington's Disease Status Based on Omics Data., PMID:33049985
An update of pathogenic variants in ASPM, WDR62, CDK5RAP2, STIL, CENPJ, and CEP135 underlying autosomal recessive primary microcephaly in 32 consanguineous families from Pakistan., PMID:32677750
Mutation in CEP135 causing primary microcephaly and subcortical heterotopia., PMID:32643282
Homozygous mutations in DZIP1 can induce asthenoteratospermia with severe MMAF., PMID:32051257
CEP135 isoform dysregulation promotes centrosome amplification in breast cancer cells., PMID:30811267
A method of quantifying centrosomes at the single-cell level in human normal and cancer tissue., PMID:30699045
The Association of CEP135 rs4865047 and NPY2R rs1902491 Single Nucleotide Polymorphisms (SNPs) with Rapid Progression of Proliferative Diabetic Retinopathy in Patients with Type 1 Diabetes Mellitus., PMID:30531682
Separation and Loss of Centrioles From Primordidal Germ Cells To Mature Oocytes In The Mouse., PMID:30143724
Differential regulation of transition zone and centriole proteins contributes to ciliary base diversity., PMID:30013109
The C-terminal region of A-kinase anchor protein 350 (AKAP350A) enables formation of microtubule-nucleation centers and interacts with pericentriolar proteins., PMID:29054927
A homozygous CEP135 mutation is associated with multiple morphological abnormalities of the sperm flagella (MMAF)., PMID:28866084
Molecular genetic analysis of consanguineous families with primary microcephaly identified pathogenic variants in the ASPM gene., PMID:28674240
A centrosome interactome provides insight into organelle assembly and reveals a non-duplication role for Plk4., PMID:27558293
The Human Centriolar Protein CEP135 Contains a Two-Stranded Coiled-Coil Domain Critical for Microtubule Binding., PMID:27477386
How the newborn centriole becomes a mother., PMID:27223270
Drosophila Ana1 is required for centrosome assembly and centriole elongation., PMID:27206860
WDR8 is a centriolar satellite and centriole-associated protein that promotes ciliary vesicle docking during ciliogenesis., PMID:26675238
A novel splice site mutation in CEP135 is associated with primary microcephaly in a Pakistani family., PMID:26657937
Conserved molecular interactions in centriole-to-centrosome conversion., PMID:26595382
Rootletin organizes the ciliary rootlet to achieve neuron sensory function in Drosophila., PMID:26483560
A Short CEP135 Splice Isoform Controls Centriole Duplication., PMID:26412126
Peri-implantation lethality in mice carrying megabase-scale deletion on 5qc3.3 is caused by Exoc1 null mutation., PMID:26346620
Cartwheel assembly., PMID:25047612
The centriolar protein Bld10/Cep135 is required to establish centrosome asymmetry in Drosophila neuroblasts., PMID:24954048
Autosomal recessive primary microcephalies (MCPH)., PMID:24780602
Multisite phosphorylation of C-Nap1 releases it from Cep135 to trigger centrosome disjunction., PMID:24695856
Abnormal centrosomal structure and duplication in Cep135-deficient vertebrate cells., PMID:23864714
For research use only. Not for human or drug use.
