SALL4-Related Disorders. PMID: 20301547
SALL4 Oncogenic Function in Cancers: Mechanisms and Therapeutic Relevance. PMID: 35216168
SALL4: An Intriguing Therapeutic Target in Cancer Treatment. PMID: 36010677
SALL4 as a transcriptional and epigenetic regulator in normal and leukemic hematopoiesis. PMID: 29308206
SALL4: an emerging cancer biomarker and target. PMID: 25444934
SALL4: engine of cell stemness. PMID: 25174577
SALL4, the missing link between stem cells, development and cancer. PMID: 26892498
Thalidomide promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray syndrome. PMID: 30067223
Epigenetic control of melanoma cell invasiveness by the stem cell factor SALL4. PMID: 34417458
SALL4 and microRNA: The Role of Let-7. PMID: 34573282
New High-Throughput Screening Identifies Compounds That Reduce Viability Specifically in Liver Cancer Cells That Express High Levels of SALL4 by Inhibiting Oxidative Phosphorylation. PMID: 31446059
Demethylation and Up-Regulation of an Oncogene after Hypomethylating Therapy. PMID: 35613022
Role of SALL4 in hematopoiesis. PMID: 22555391
Potential application of human SALL4 on oral squamous cell carcinoma. PMID: 36172107
Functional and clinical significance of SALL4 in breast cancer. PMID: 27444278
The teratogenic effects of thalidomide on limbs. PMID: 30335598
Oncofetal gene SALL4 and prognosis in cancer: A systematic review with meta-analysis. PMID: 28160555
Recent updates in thoracic SMARCA4-deficient undifferentiated tumor. PMID: 34147303
Sall4 Guides p53-Mediated Enhancer Interference upon DNA Damage in Mouse Embryonic Stem Cells. PMID: 35977539
Sall4 in "stemness"-driven hepatocarcinogenesis. PMID: 23758237
SALL4 promotes gastric cancer progression via hexokinase II mediated glycolysis. PMID: 32489324
Recent advances in the molecular mechanism of thalidomide teratogenicity. PMID: 32304852
Targeting an Inducible SALL4-Mediated Cancer Vulnerability with Sequential Therapy. PMID: 34593523
SALL4 is a useful marker for pediatric yolk sac tumors. PMID: 32222813
The role of stem cell factor SALL4 in leukemogenesis. PMID: 22150312
Crystal structure of the SALL4-pomalidomide-cereblon-DDB1 complex. PMID: 32251415
SALL4 promotes tumor progression in breast cancer by targeting EMT. PMID: 32835442
SMARCA4/BRG1-Deficient Non-Small Cell Lung Carcinomas: A Case Series and Review of the Literature. PMID: 33367658
Serum SALL4 as a predictive biomarker for the prognosis of patients with hepatocellular carcinoma who underwent nonsurgical treatment. PMID: 36316931
SALL4 activates PI3K/AKT signaling pathway through targeting PTEN, thus facilitating migration, invasion and proliferation of hepatocellular carcinoma cells. PMID: 36575044
Role of SALL4 in HER2+ Breast Cancer Progression: Regulating PI3K/AKT Pathway. PMID: 36362083
SALL4 controls cell fate in response to DNA base composition. PMID: 33406384
Dedifferentiation and the role of sall4 in reprogramming and patterning during amphibian limb regeneration. PMID: 21305648
SALL4 Gene Expression in Acute Myeloid Leukemia. PMID: 31653163
Duane Syndrome. PMID: 20301369
Oncofetal SALL4-Driven Tumorigenesis Is Highly Dependent on Oxidative Phosphorylation, Revealing Therapeutic Opportunities. PMID: 31606470
SALL4 promotes osteoblast differentiation by deactivating NOTCH2 signaling. PMID: 29241074
Targeting SALL4 by entinostat in lung cancer. PMID: 27705911
SALL4 Expression in Epithelial Gastric Cancer: Epigenetic or Epiphenomenon? PMID: 36877335
SALL4 induces radioresistance in nasopharyngeal carcinoma via the ATM/Chk2/p53 pathway. PMID: 30907073
Sall4 regulates neuromesodermal progenitors and their descendants during body elongation in mouse embryos. PMID: 31235634
SALL4 promotes gastric cancer progression through activating CD44 expression. PMID: 27819668
Up-Regulation of SALL4 Is Associated With Survival and Progression via Putative WNT Pathway in Gastric Cancer. PMID: 33644042
SALL4 activates TGF-β/SMAD signaling pathway to induce EMT and promote gastric cancer metastasis. PMID: 30349378
SALL4 mediates teratogenicity as a thalidomide-dependent cereblon substrate. PMID: 30190590
Effect of SALL4 on the Proliferation, Invasion and Apoptosis of Breast Cancer Cells. PMID: 33308020
SALL4 is a marker of the embryonal subtype of hepatoblastoma. PMID: 23822878
Regulatory effect of MiR103 on proliferation, EMT and invasion of oral squamous carcinoma cell through SALL4. PMID: 33577002
Zinc Finger Protein SALL4 Functions through an AT-Rich Motif to Regulate Gene Expression. PMID: 33406418
SOX2/SALL4 stemness axis modulates Notch signaling genes to maintain self-renewal capacity of esophageal squamous cell carcinoma. PMID: 33098486
CK19-positive Hepatocellular Carcinoma is a Characteristic Subtype. PMID: 32742454
Maternal Sall4 Is Indispensable for Epigenetic Maturation of Mouse Oocytes. PMID: 28031467
SALL4 correlates with proliferation, metastasis, and poor prognosis in prostate cancer by affecting MAPK pathway. PMID: 37119046
SALL4 is a new target in endometrial cancer. PMID: 24336327
SALL4 promotes glycolysis and chromatin remodeling via modulating HP1α-Glut1 pathway. PMID: 28759035
SALL4 is a novel therapeutic target in intrahepatic cholangiocarcinoma. PMID: 26317546
SALL4 oncogene is an immunogenic antigen presented in various HLA-DR contexts. PMID: 29632725
Knockdown of SALL4 inhibits the proliferation, migration, and invasion of human lung cancer cells in vivo and in vitro. PMID: 33490190
Expression and clinical value of SALL4 in renal cell carcinomas. PMID: 32468053
The Invasion and Metastasis of Colon Adenocarcinoma (COAD) Induced by SALL4. PMID: 35692499
The NuRD complex cooperates with SALL4 to orchestrate reprogramming. PMID: 37208322
SALL4-related gene signature defines a specific stromal subset of pancreatic ductal adenocarcinoma with poor prognostic features. PMID: 36587397
Sall4 and Myocd Empower Direct Cardiac Reprogramming From Adult Cardiac Fibroblasts After Injury. PMID: 33718351
SALL4 promotes the tumorigenicity of cervical cancer cells through activation of the Wnt/β-catenin pathway via CTNNB1. PMID: 31336010
Role of SALL4 and Nodal in the prognosis and tamoxifen resistance of estrogen receptor-positive breast cancer. PMID: 34476264
Sall4 overexpression blocks murine hematopoiesis in a dose-dependent manner. PMID: 25246269
Transcriptome analysis reveals SALL4 as a prognostic key gene in gastric adenocarcinoma. PMID: 35284980
Normal embryonic development and neonatal digit regeneration in mice overexpressing a stem cell factor, Sall4. PMID: 35482646
Identification of SALL4 Expressing Islet-1+ Cardiovascular Progenitor Cell Clones. PMID: 36675298
Spalt-Like Protein 4 (SALL4) Promotes Angiogenesis by Activating Vascular Endothelial Growth Factor A (VEGFA) Signaling. PMID: 32116289
Study on the mechanism of SALL4 down-regulation in promoting the invasion and migration of oral squamous cell carcinoma and influencing the survival and prognosis of patients. PMID: 35965794
The Study of SALL4 Gene and BMI-1 Gene Expression in Acute Myeloid Leukemia Patients. PMID: 31552409
Retraction notice to MicroRNA-98 Plays a Suppressive Role in Non-Small Cell Lung Cancer Through Inhibition of SALL4 Protein Expression [Oncology Research 25(6) (2017) 975-988]. PMID: 34503608
SALL4 suppresses PTEN expression to promote glioma cell proliferation via PI3K/AKT signaling pathway. PMID: 28887597
SALL4, a novel marker for human gastric carcinogenesis and metastasis. PMID: 24276240
SALL4 as a new biomarker for early colorectal cancers. PMID: 25156818
Targeting neuroinflammation: 3-monothiopomalidomide a new drug candidate to mitigate traumatic brain injury and neurodegeneration., PMID:40524167
Hepatic Yolk Sac Tumor: A Systematic Review of Presentation, Diagnosis, and Treatment., PMID:40498239
A de novo SALL4 mutation causes unilateral renal agenesis by misregulating genes involved in kidney development., PMID:40483479
Concurrent SMARCA4-deficient and poorly differentiated adenocarcinomas in separate lung lobes: a case report and literature review., PMID:40405273
A novel conditionally replicative oncolytic adenovirus under the control of the SALL4 promoter inhibits the growth of rhabdoid tumors., PMID:40386952
Targeting transcription factors through an IMiD independent zinc finger domain., PMID:40369156
Overcoming CK1α liability in the discovery of a series of isoIndolinone Glutarimides as selective IKZF2 molecular glue degraders., PMID:40334997
[Articular and periarticular tumors : Important diagnoses in rheumatology and orthopedic rheumatology]., PMID:40323421
[Characteristics of non-small cell lung carcinoma with trophoblastic differentiation in males: a clinicopathological analysis of 16 cases]., PMID:40302577
Colorectal cancer progression to metastasis is associated with dynamic genome-wide biphasic 5-hydroxymethylcytosine accumulation., PMID:40241172
Thalidomide-induced limb malformations: an update and reevaluation., PMID:40198353
Monoselective Histone Deacetylase 6 PROTAC Degrader Shows In Vivo Tractability., PMID:40063353
SALL4/ABCB6 Axis Suppresses Ferroptosis in Colon Cancer by Mediating Mitophagy., PMID:40052371
USP37-stabilized SALL4 promotes the keloid formation by PI3K/AKT pathway., PMID:40038378
ZBTB16/PLZF regulates juvenile spermatogonial stem cell development through an extensive transcription factor poising network., PMID:40033150
Nonclinical teratogenicity safety assessment of CRBN-engaging targeted protein degraders: Points to consider., PMID:40015443
GC-MSCs transcriptionally upregulate SALL4 in gastric cancer through miR-4669/TIMP3/β-catenin signaling., PMID:39965736
Emerging Insights into Sall4's Role in Cardiac Regenerative Medicine., PMID:39936946
Genomic landscape and potential therapeutic targets in alpha-fetoprotein-producing gastric cancer., PMID:39928247
Yolk Sac Tumor of the Liver: An Important Differential for Liver Mass with Elevated Serum Alpha-Fetoprotein in the Pediatric Population., PMID:39907271
Cytoplasmic SALL4-A isoform expression as a diagnostic marker of less aggressive tumor behavior in gastric cancer., PMID:39905414
The regulatory repertoire of ZBTB16 in porcine immature spermatogonia., PMID:39893798
SALL4 as a Useful Marker for the Distinction of Various Gestational Trophoblastic Disease Subtypes: Choriocarcinoma From Other Trophoblastic Lesions and Early Complete Hydatidiform Mole From Partial Mole and NonMolar Villi., PMID:39876093
Complex immunohistochemical and molecular study on 5 cases of ovarian juvenile granulosa cell tumors reveals a consistent alteration in the PI3K/AKT/mTOR signaling pathway., PMID:39773640
Paratesticular/inguinal SMARCB1/INI1 deficient carcinomas with yolk sac tumour-like differentiation are aggressive somatic malignancies., PMID:39762201
Reconstitution of pluripotency from mouse fibroblast through Sall4 overexpression., PMID:39737935
SALL4 mediates SHP2 inhibition in myocardial fibroblasts through the DOT1L/H3K79me2 signaling pathway to promote the progression of myocardial infarction., PMID:39730739
[Primary uterine hepatoid adenocarcinoma: Clinicopathological analysis of 2 cases and literature review]., PMID:39690782
[Primary intracranial DICER1-mutant sarcoma: a clinicopathological analysis of seven cases]., PMID:39648006
[Small cell carcinoma of the ovary of hypercalcaemic type: a clinicopathological analysis of sixteen cases]., PMID:39648003
Comprehensive RNA Sequencing Analysis Identifies Network Hub Genes and Biomarkers Differentiating Desmoid-type Fibromatosis From Reactive Fibrosis., PMID:39617099
Cell-type specific, inducible and acute degradation of targeted protein in mice by two degron systems., PMID:39613744
Epithelioid trophoblastic tumor in male patients with germ cell tumor: A clinicopathologic analysis of five cases., PMID:39461379
Conserved helical motifs in the IKZF1 disordered region mediate NuRD interaction and transcriptional repression., PMID:39437550
SALL4 and C-kit positive malignant extrarenal rhabdoid tumor of the pelvis in a child: A diagnostic and therapeutic challenge., PMID:39412932
Sall4 and Gata4 induce cardiac fibroblast transition towards a partially multipotent state with cardiogenic potential., PMID:39406776
Gastric adenocarcinoma with intestinal progenitor cell differentiation: a morphologically underdiagnosed and more invasive distinctive type of gastric adenocarcinoma., PMID:39267675
DICER1-sarcomas of GYN tract: Expanding on an emerging entity., PMID:39127354
Exploring SALL4 as a significant prognostic marker in breast cancer and its association with progression pathways involved in cancer genesis., PMID:39098137
Cell fate decision by a morphogen-transcription factor-chromatin modifier axis., PMID:39075094
Sall4 regulates downstream patterning genes during limb regeneration., PMID:39067503
Engineering mouse cell fate controller by rational design., PMID:39043686
[Clinicopathological analysis of gastric adenocarcinoma with elevated serum alpha-fetoprotein and enteroblastic differentiation]., PMID:39034804
Assessment of Molecular Markers in Pediatric Ovarian Tumors: Romanian Single-Center Experience., PMID:38928458
Revisiting the antiangiogenic mechanisms of fluorinated thalidomide derivatives., PMID:38917956
SALL4 upregulates brain-derived neurotrophic factor to mediate Hedgehog signaling to inhibit carboplatin sensitivity in colon adenocarcinoma., PMID:38884945
Human Genetics of Ventricular Septal Defect., PMID:38884729
Gastric SMARCA4-deficient undifferentiated tumor (SMARCA4-UT): a clinicopathological analysis of four rare cases., PMID:38877473
Fetal gut cell-like differentiation in esophageal adenocarcinoma defines a rare tumor subtype with therapeutically relevant claudin-6 positivity and SWI/SNF gene alteration., PMID:38866822
Differential Analysis of Cereblon Neosubstrates in Rabbit Embryos Using Targeted Proteomics., PMID:38866076
For research use only. Not for human or drug use.
