YES1: A Novel Therapeutic Target and Biomarker in Cancer. PMID: 35732509
YES1 Is a Druggable Oncogenic Target in SCLC. PMID: 35988891
EphA2-YES1-ANXA2 pathway promotes gastric cancer progression and metastasis. PMID: 33941853
Peptide SMIM30 promotes HCC development by inducing SRC/YES1 membrane anchoring and MAPK pathway activation. PMID: 32461121
miR-133a targets YES1 to reduce cisplatin resistance in ovarian cancer by regulating cell autophagy. PMID: 35012539
YES1 activation induces acquired resistance to neratinib in HER2-amplified breast and lung cancers. PMID: 31856375
YES1 Drives Lung Cancer Growth and Progression and Predicts Sensitivity to Dasatinib. PMID: 31166114
RBM15 promotes hepatocellular carcinoma progression by regulating N6-methyladenosine modification of YES1 mRNA in an IGF2BP1-dependent manner. PMID: 34707107
YES1 as a Therapeutic Target for HER2-Positive Breast Cancer after Trastuzumab and Trastuzumab-Emtansine (T-DM1) Resistance Development. PMID: 34884609
Preventing Engrailed-1 activation in fibroblasts yields wound regeneration without scarring. PMID: 33888614
Correction to: EphA2-YES1-ANXA2 pathway promotes gastric cancer progression and metastasis. PMID: 35046536
To Scar or Not to Scar. PMID: 34320296
Yes1 signaling mediates the resistance to Trastuzumab/Lap atinib in breast cancer. PMID: 28158234
YES1 and MYC Amplifications as Synergistic Resistance Mechanisms to Different Generation ALK Tyrosine Kinase Inhibitors in Advanced NSCLC: Brief Report of Clinical and Preclinical Proofs. PMID: 35199053
Retraction. PMID: 34383338
Overexpression of YES1 is associated with favorable prognosis and increased platinum-sensitivity in patients with epithelial ovarian cancer. PMID: 31970720
SRC Family Kinase Inhibition Targets YES1 and YAP1 as Primary Drivers of Lung Cancer and as Mediators of Acquired Resistance to ALK and Epidermal Growth Factor Receptor Inhibitors. PMID: 35952318
Downregulation of circ-YES1 suppresses NSCLC migration and proliferation through the miR-142-3p-HMGB1 axis. PMID: 37009887
YES1 amplification confers trastuzumab-emtansine (T-DM1) resistance in HER2-positive cancer. PMID: 32572172
Matrine Regulates Proliferation, Apoptosis, Cell Cycle, Migration, and Invasion of Non-Small Cell Lung Cancer Cells Through the circFUT8/miR-944/YES1 Axis [Retraction]. PMID: 36545224
Etv2 transcriptionally regulates Yes1 and promotes cell proliferation during embryogenesis. PMID: 31278282
YES1 activation elicited by heat stress is anti-apoptotic in mouse pachytene spermatocytes. PMID: 24132961
YES1 Is a Targetable Oncogene in Cancers Harboring YES1 Gene Amplification. PMID: 31391186
Targeting VEGF-A/VEGFR2 Y949 Signaling-Mediated Vascular Permeability Alleviates Hypoxic Pulmonary Hypertension. PMID: 36384284
YES1 amplification is a mechanism of acquired resistance to EGFR inhibitors identified by transposon mutagenesis and clinical genomics. PMID: 29875142
Long non-coding TUG1 accelerates prostate cancer progression through regulating miR-128-3p/YES1 axis. PMID: 32016963
Identification of potent Yes1 kinase inhibitors using a library screening approach. PMID: 23787099
METTL3 promotes colorectal carcinoma progression by regulating the m6A-CRB3-Hippo axis. PMID: 35012593
Influence of YES1 Kinase and Tyrosine Phosphorylation on the Activity of OCT1. PMID: 33790797
MicroRNA-133a inhibits the proliferation of non-small cell lung cancer by targeting YES1. PMID: 31807185
MiR-199a suppresses prostate cancer paclitaxel resistance by targeting YES1. PMID: 29204706
ASB13 inhibits breast cancer metastasis through promoting SNAI2 degradation and relieving its transcriptional repression of YAP. PMID: 32943576
MiR-133 Targets YES1 and Inhibits the Growth of Triple-Negative Breast Cancer Cells. PMID: 32462982
Circ_0057553/miR-515-5p Regulates Prostate Cancer Cell Proliferation, Apoptosis, Migration, Invasion and Aerobic Glycolysis by Targeting YES1. PMID: 33177837
Scribble sub-cellular localization modulates recruitment of YES1 to regulate YAP1 phosphorylation. PMID: 33730553
Circ_0081143 Contributes to Gastric Cancer Malignant Development and Doxorubicin Resistance by Elevating the Expression of YES1 by Targeting mziR-129-2-3p. PMID: 35686503
Bioactive Phytoconstituents as Potent Inhibitors of Tyrosine-Protein Kinase Yes (YES1): Implications in Anticancer Therapeutics. PMID: 35630545
Targeting Yes1 Associated Transcriptional Regulator Inhibits Hepatocellular Carcinoma Progression and Improves Sensitivity to Sorafenib: An in vitro and in vivo Study. PMID: 33149619
Predictive Biomarkers of Response to Src Inhibitors in Lung Cancer. Getting to YES1. PMID: 31206303
The chaperone-assisted selective autophagy complex dynamics and dysfunctions. PMID: 36594740
Linkage disequilibrium and haplotype analysis of Src and Yes1 genes in thyroid cancer. PMID: 32253932
Correction: Yes1 signaling mediates the resistance to Trastuzumab/Lap atinib in breast cancer. PMID: 28301577
MiR-17-5p up-regulates YES1 to modulate the cell cycle progression and apoptosis in ovarian cancer cell lines. PMID: 25561420
Up-regulation of microRNA-210 inhibits proliferation of hepatocellular carcinoma cells by targeting YES1. PMID: 26676187
Personalized Cancer Therapy: YES1 Is the New Kid on the Block. PMID: 31772072
Matrine Regulates Proliferation, Apoptosis, Cell Cycle, Migration, and Invasion of Non-Small Cell Lung Cancer Cells Through the circFUT8/miR-944/YES1 Axis. PMID: 33907466
Role of YES1 amplification in EGFR mutation-positive non-small cell lung cancer: Primary resistance to afatinib in a patient. PMID: 32744377
Deubiquitinase ubiquitin-specific peptidase 10 maintains cysteine rich angiogenic inducer 61 expression via Yes1 associated transcriptional regulator to augment immune escape and metastasis of pancreatic adenocarcinoma. PMID: 35271750
Linc01133 contributes to gastric cancer growth by enhancing YES1-dependent YAP1 nuclear translocation via sponging miR-145-5p. PMID: 35017464
Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression. PMID: 35012996
[miR-133b inhibits myocardial ischemia-reperfusion-induced cardiomyocyte apoptosis and accumulation of reactive oxygen species in rats by targeting YES1]. PMID: 33118509
Loss of acinar cell VMP1 triggers spontaneous pancreatitis in mice. PMID: 34709991
Impaired degradation of YAP1 and IL6ST by chaperone-mediated autophagy promotes proliferation and migration of normal and hepatocellular carcinoma cells. PMID: 35435804
β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis. PMID: 23245941
P4HA2 induces hepatic ductular reaction and biliary fibrosis in chronic cholestatic liver diseases. PMID: 36799463
SIX4 promotes hepatocellular carcinoma metastasis through upregulating YAP1 and c-MET. PMID: 33046796
Transcriptome and proteome profile analysis of the regulation of chicken ovarian development., PMID:40466268
Nanomaterial-based biosensors for cancer diagnosis: trends and innovations (2022-2025)., PMID:40465004
MicroRNA-142-3p Overcomes Drug Resistance in Hepatocellular Carcinoma by Targeting YES1 and TWF1., PMID:40362400
Candidate Biomarkers YES1, Troponin I, Lactate, and Ammonia for Evaluation of Cardiac Function Post Hypothermic Oxygenated Perfusion., PMID:40131761
The Hippo pathway effector YAP inhibits NF-κB signaling and ccRCC growth by opposing ZHX2., PMID:40120683
YAP1 regulates endometrial receptivity by promoting the plasma membrane transformation and proliferation of bovine endometrial epithelial cells., PMID:40024019
Autophagy induced by mechanical stress sensitizes cells to ferroptosis by NCOA4-FTH1 axis., PMID:39988734
Overexpression of SHANK2 contributes malignant outcomes as a Hippo pathway regulator in gastric cancer., PMID:39949934
The Moonlighting Function of Glutaminase 2 Promotes Immune Evasion of Pancreatic Ductal Adenocarcinoma by Tubulin Tyrosine Ligase-like 1-Mediated Yes1 Associated Transcriptional Regulator Glutamylation., PMID:39924055
Exploiting YES1-Driven EGFR Expression Improves the Efficacy of EGFR Inhibitors., PMID:39847459
Increased spatial coupling of integrin and collagen IV in the immunoresistant clear-cell renal-cell carcinoma tumor microenvironment., PMID:39639369
The YAP1-MAML2 fusion drives tumorigenesis and sustains tumor growth., PMID:39624057
CircINADL promotes nasopharyngeal carcinoma metastasis by inhibiting HuR ubiquitin degradation and disrupting the hippo signaling pathway., PMID:39586520
Myofibroblast-derived extracellular vesicles facilitate cancer stemness of hepatocellular carcinoma via transferring ITGA5 to tumor cells., PMID:39574133
The tyrosine kinase Yes1 is a druggable host factor of HEV., PMID:39560373
The SRC-family serves as a therapeutic target in triple negative breast cancer with acquired resistance to chemotherapy., PMID:39390250
The Induction of Drug Uptake Transporter Organic Anion Transporting Polypeptide 1A2 by Radiation Is Mediated by the Nonreceptor Tyrosine Kinase v-YES-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1., PMID:39214663
FASLG as a Key Member of Necroptosis Participats in Acute Myocardial Infarction by Regulating Immune Infiltration., PMID:39205966
ITCH inhibits alkaliptosis in human pancreatic cancer cells through YAP1-dependent SLC16A1 activation., PMID:39179170
YAP Alleviates Pulmonary Fibrosis Through Promoting Alveolar Regeneration via Modulating the Stemness of Alveolar Type 2 Cells., PMID:39119800
Syngeneic mouse model of YES-driven metastatic and proliferative hepatocellular carcinoma., PMID:39051113
Targeting YES1 Disrupts Mitotic Fidelity and Potentiates the Response to Taxanes in Triple-Negative Breast Cancer., PMID:39037997
Neuromedin S regulates goat ovarian granulosa cell proliferation and steroidogenesis via endoplasmic reticulum Ca2+-YAP1-ATF4-c-Jun pathway., PMID:38982727
ACSL3 regulates breast cancer progression via lipid metabolism reprogramming and the YES1/YAP axis., PMID:38953696
NUAK2 Inhibitors, KHKI-01128 and KHKI-01215, Exhibit Potent Anticancer Activity Against SW480 Colorectal Cancer Cells., PMID:38925848
A Novel tsRNA, m7G-3' tiRNA LysTTT, Promotes Bladder Cancer Malignancy Via Regulating ANXA2 Phosphorylation., PMID:38894581
FAT1 inhibits the proliferation of DLBCL cells via increasing the m6A modification of YAP1 mRNA., PMID:38782965
Overexpression of transcription factor TBX5 inhibits the activation of YAP1-TEAD1 pathway to promote ferroptosis in lung cancer cells., PMID:38735135
Blockade of a novel MAP4K4-LATS2-SASH1-YAP1 cascade inhibits tumorigenesis and metastasis in luminal breast cancer., PMID:38657867
Amelioration of NAFLD by sleeve gastrectomy-triggered hepatocyte regeneration in mice - experimental research., PMID:38573134
YAP1/TAZ Mediates Rumen Epithelial Cell Proliferation but Not Short-Chain Fatty Acid Metabolism In Vitro., PMID:38540020
Identification of clinical characteristics biomarkers for rheumatoid arthritis through targeted DNA methylation sequencing., PMID:38508093
YES1 as a potential target to overcome drug resistance in EGFR-deregulated non-small cell lung cancer., PMID:38443724
NAT10-mediated ac4C-modified ANKZF1 promotes tumor progression and lymphangiogenesis in clear-cell renal cell carcinoma by attenuating YWHAE-driven cytoplasmic retention of YAP1., PMID:38407929
Emerging Roles of YES1 in Cancer: The Putative Target in Drug Resistance., PMID:38338729
AURKA inhibition induces Ewing's sarcoma apoptosis and ferroptosis through NPM1/YAP1 axis., PMID:38287009
Prostatitis No.1 traditional chinese medicine significantly exhibited anti-inflammation role on prostatitis through miR-205-5p/YES1., PMID:38279415
LATS1 Promotes B-ALL Tumorigenesis by Regulating YAP1 Phosphorylation and Subcellular Localization., PMID:38277019
Therapeutic strategy using novel RET/YES1 dual-target inhibitor in lung cancer., PMID:38198957
KZL204, a Trifluoromethylated Quinazoline Derivative, Exhibits High Potent Anti-Tumor Effects on Glioblastoma Multiforme U251MG Cells., PMID:38182147
Combined BET and MEK Inhibition synergistically suppresses melanoma by targeting YAP1., PMID:38169595
LncRNA12097.1 contributes to endometrial cell growth by enhancing YES1 activating β-catenin via sponging miR-145-5p., PMID:38035963
Increased spatial coupling of integrin and collagen IV in the immunoresistant clear cell renal cell carcinoma tumor microenvironment., PMID:38014063
Electroacupuncture alleviates neurological function via activating the Yap-OPA1 axis and mitochondrial fusion in rats with cerebral ischemia-reperfusion injury., PMID:37984905
Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis., PMID:37936984
Itga8-Cre-mediated deletion of YAP and TAZ impairs bladder contractility with minimal inflammation and chondrogenic differentiation., PMID:37927241
Molecular mechanisms of AMPK/YAP/NLRP3 signaling pathway affecting the occurrence and development of ankylosing spondylitis., PMID:37925428
Actin polymerization inhibition by targeting ARPC2 affects intestinal stem cell homeostasis., PMID:37849945
Distinct microRNA Signature and Suppression of ZFP36L1 Define ASCL1-Positive Lung Adenocarcinoma., PMID:37801008
Molecular subtypes, predictive markers and prognosis in small-cell lung carcinoma., PMID:37775262
For research use only. Not for human or drug use.
