The lysosomal disease caused by mutant VPS33A. PMID: 31070736
Structural basis of Vps33A recruitment to the human HOPS complex by Vps16. PMID: 23901104
Juvenile mucopolysaccharidosis plus disease caused by a missense mutation in VPS33A. PMID: 36153662
A VPS33A-binding motif on syntaxin 17 controls autophagy completion in mammalian cells. PMID: 30655294
Recruitment of VPS33A to HOPS by VPS16 Is Required for Lysosome Fusion with Endosomes and Autophagosomes. PMID: 25783203
Vps33a mediates RANKL storage in secretory lysosomes in osteoblastic cells. PMID: 19419298
The Vps33a gene regulates behavior and cerebellar Purkinje cell number. PMID: 19254700
Mutation in VPS33A affects metabolism of glycosaminoglycans: a new type of mucopolysaccharidosis with severe systemic symptoms. PMID: 28013294
Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B. PMID: 29778605
Impairment of autophagosome-lysosome fusion in the buff mutant mice with the VPS33A(D251E) mutation. PMID: 26259518
Mucopolysaccharidosis-Plus Syndrome: Report on a Polish Patient with a Novel VPS33A Variant with Comparison with Other Described Patients. PMID: 36232726
Mucopolysaccharidosis-Plus Syndrome. PMID: 31936524
Involvement of vps33a in the fusion of uroplakin-degrading multivesicular bodies with lysosomes. PMID: 19566896
The SM protein Car/Vps33A regulates SNARE-mediated trafficking to lysosomes and lysosome-related organelles. PMID: 19158398
A probable new syndrome with the storage disease phenotype caused by the VPS33A gene mutation. PMID: 27547915
The mouse organellar biogenesis mutant buff results from a mutation in Vps33a, a homologue of yeast vps33 and Drosophila carnation. PMID: 12538872
Comparative evolutionary analysis of VPS33 homologues: genetic and functional insights. PMID: 15790593
The HOPS complex mediates autophagosome-lysosome fusion through interaction with syntaxin 17. PMID: 24554770
Elevated pulmonary tuberculosis biomarker miR-423-5p plays critical role in the occurrence of active TB by inhibiting autophagosome-lysosome fusion. PMID: 30898038
The road to lysosome-related organelles: Insights from Hermansky-Pudlak syndrome and other rare diseases. PMID: 30945407
Bi-allelic VPS16 variants limit HOPS/CORVET levels and cause a mucopolysaccharidosis-like disease. PMID: 33938619
Hematopoietic Disorders, Renal Impairment and Growth in Mucopolysaccharidosis-Plus Syndrome. PMID: 35628659
Accumulation of autophagosomes confers cytotoxicity. PMID: 28673965
Vps33B is required for delivery of endocytosed cargo to lysosomes. PMID: 26403612
Restriction factor screening identifies RABGAP1L-mediated disruption of endocytosis as a host antiviral defense. PMID: 35320721
Distinct roles of the two VPS33 proteins in the endolysosomal system in Caenorhabditis elegans. PMID: 27558849
Homozygous missense VPS16 variant is associated with a novel disease, resembling mucopolysaccharidosis-plus syndrome in two siblings. PMID: 34013567
MiniCORVET is a Vps8-containing early endosomal tether in Drosophila. PMID: 27253064
Mucopolysaccharidosis-Plus Syndrome, a Rapidly Progressive Disease: Favorable Impact of a Very Prolonged Steroid Treatment on the Clinical Course in a Child. PMID: 35327996
Frameshift mutations of vacuolar protein sorting genes in gastric and colorectal cancers with microsatellite instability. PMID: 21733561
Loss of Acot12 contributes to NAFLD independent of lipolysis of adipose tissue. PMID: 34285335
Triphenyltin exposure induced abnormal morphological colouration in adult male guppies (Poecilia reticulata). PMID: 35905627
The Drosophila pigmentation gene pink (p) encodes a homologue of human Hermansky-Pudlak syndrome 5 (HPS5). PMID: 17156100
Vps33b pathogenic mutations preferentially affect VIPAS39/SPE-39-positive endosomes. PMID: 23918659
Mammalian homologues of yeast vacuolar protein sorting (vps) genes implicated in Golgi-to-lysosome trafficking. PMID: 8996080
Bi-allelic variants in HOPS complex subunit VPS41 cause cerebellar ataxia and abnormal membrane trafficking. PMID: 33764426
The Sec1-Munc18 protein VPS33B forms a uniquely bidirectional complex with VPS16B. PMID: 37062417
A reversible autophagy inhibitor blocks autophagosome-lysosome fusion by preventing Stx17 loading onto autophagosomes. PMID: 31188703
Targeting protein-trafficking pathways alters melanoma treatment sensitivity. PMID: 22203954
Interaction of the HOPS complex with Syntaxin 17 mediates autophagosome clearance in Drosophila. PMID: 24554766
Multidrug resistance decreases with mutations of melanosomal regulatory genes. PMID: 19155314
Molecular cloning and characterization of human VPS18, VPS 11, VPS16, and VPS33. PMID: 11250079
SPE-39 family proteins interact with the HOPS complex and function in lysosomal delivery. PMID: 19109425
A high throughput, functional screen of human Body Mass Index GWAS loci using tissue-specific RNAi Drosophila melanogaster crosses. PMID: 29608557
[Cloning to rule out 10 candidate genes located in chromosome 12q24 for Charcot-Marie-Tooth disease type 2L]. PMID: 16604494
Normal lytic granule secretion by cytotoxic T lymphocytes deficient in BLOC-1, -2 and -3 and myosins Va, VIIa and XV. PMID: 15702992
Mucopolysaccharidosis-Plus Syndrome: Is This a Type of Mucopolysaccharidosis or a Separate Kind of Metabolic Disease?, PMID:39273517
Domain 3a mutation of VPS33A suppresses larval arrest phenotype in the loss of VPS45 in Caenorhabditis elegans., PMID:38585203
The hookup model of the HOPS complex in autophagosome-lysosome fusion., PMID:38083843
Integrative proteome and metabolome analyses reveal molecular basis underlying growth and nutrient composition in the Pacific oyster, Crassostrea gigas., PMID:37838097
The Sec1-Munc18 protein VPS33B forms a uniquely bidirectional complex with VPS16B., PMID:37062417
Mucopolysaccharidosis-Plus Syndrome: Report on a Polish Patient with a Novel VPS33A Variant with Comparison with Other Described Patients., PMID:36232726
Juvenile mucopolysaccharidosis plus disease caused by a missense mutation in VPS33A., PMID:36153662
Hematopoietic Disorders, Renal Impairment and Growth in Mucopolysaccharidosis-Plus Syndrome., PMID:35628659
Restriction factor screening identifies RABGAP1L-mediated disruption of endocytosis as a host antiviral defense., PMID:35320721
Loss of Acot12 contributes to NAFLD independent of lipolysis of adipose tissue., PMID:34285335
Homozygous missense VPS16 variant is associated with a novel disease, resembling mucopolysaccharidosis-plus syndrome in two siblings., PMID:34013567
Bi-allelic VPS16 variants limit HOPS/CORVET levels and cause a mucopolysaccharidosis-like disease., PMID:33938619
Bi-allelic variants in HOPS complex subunit VPS41 cause cerebellar ataxia and abnormal membrane trafficking., PMID:33764426
A reversible autophagy inhibitor blocks autophagosome-lysosome fusion by preventing Stx17 loading onto autophagosomes., PMID:31188703
The lysosomal disease caused by mutant VPS33A., PMID:31070736
Elevated pulmonary tuberculosis biomarker miR-423-5p plays critical role in the occurrence of active TB by inhibiting autophagosome-lysosome fusion., PMID:30898038
A VPS33A-binding motif on syntaxin 17 controls autophagy completion in mammalian cells., PMID:30655294
Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B., PMID:29778605
Accumulation of autophagosomes confers cytotoxicity., PMID:28673965
Mutation in VPS33A affects metabolism of glycosaminoglycans: a new type of mucopolysaccharidosis with severe systemic symptoms., PMID:28013294
Distinct roles of the two VPS33 proteins in the endolysosomal system in Caenorhabditis elegans., PMID:27558849
A probable new syndrome with the storage disease phenotype caused by the VPS33A gene mutation., PMID:27547915
MiniCORVET is a Vps8-containing early endosomal tether in Drosophila., PMID:27253064
Vps33B is required for delivery of endocytosed cargo to lysosomes., PMID:26403612
Impairment of autophagosome-lysosome fusion in the buff mutant mice with the VPS33A(D251E) mutation., PMID:26259518
Recruitment of VPS33A to HOPS by VPS16 Is Required for Lysosome Fusion with Endosomes and Autophagosomes., PMID:25783203
The HOPS complex mediates autophagosome-lysosome fusion through interaction with syntaxin 17., PMID:24554770
Interaction of the HOPS complex with Syntaxin 17 mediates autophagosome clearance in Drosophila., PMID:24554766
Vps33b pathogenic mutations preferentially affect VIPAS39/SPE-39-positive endosomes., PMID:23918659
Structural basis of Vps33A recruitment to the human HOPS complex by Vps16., PMID:23901104
Targeting protein-trafficking pathways alters melanoma treatment sensitivity., PMID:22203954
Frameshift mutations of vacuolar protein sorting genes in gastric and colorectal cancers with microsatellite instability., PMID:21733561
Involvement of vps33a in the fusion of uroplakin-degrading multivesicular bodies with lysosomes., PMID:19566896
Vps33a mediates RANKL storage in secretory lysosomes in osteoblastic cells., PMID:19419298
The Vps33a gene regulates behavior and cerebellar Purkinje cell number., PMID:19254700
The SM protein Car/Vps33A regulates SNARE-mediated trafficking to lysosomes and lysosome-related organelles., PMID:19158398
Multidrug resistance decreases with mutations of melanosomal regulatory genes., PMID:19155314
SPE-39 family proteins interact with the HOPS complex and function in lysosomal delivery., PMID:19109425
The Drosophila pigmentation gene pink (p) encodes a homologue of human Hermansky-Pudlak syndrome 5 (HPS5)., PMID:17156100
Comparative evolutionary analysis of VPS33 homologues: genetic and functional insights., PMID:15790593
Normal lytic granule secretion by cytotoxic T lymphocytes deficient in BLOC-1, -2 and -3 and myosins Va, VIIa and XV., PMID:15702992
The mouse organellar biogenesis mutant buff results from a mutation in Vps33a, a homologue of yeast vps33 and Drosophila carnation., PMID:12538872
Molecular cloning and characterization of human VPS18, VPS 11, VPS16, and VPS33., PMID:11250079
Mammalian homologues of yeast vacuolar protein sorting (vps) genes implicated in Golgi-to-lysosome trafficking., PMID:8996080
For research use only. Not for human or drug use.
