Catalog No.
YHE41001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser82-Glu198
Predicted molecular weight
15.49 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P43307
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
TRAPA, TRAP-alpha, Translocon-associated protein subunit alpha, SSR-alpha, SSR1, Signal sequence receptor subunit alpha
Blood SSR1: A Possible Biomarker for Early Prediction of Parkinson's Disease. PMID: 35310885
SSR1 is involved in maintaining the function of mitochondria electron transport chain and iron homeostasis upon proline treatment in Arabidopsis. PMID: 33271443
RP11‑156L14.1 regulates SSR1 expression by competitively binding to miR‑548ao‑3p in hypopharyngeal squamous cell carcinoma. PMID: 33000261
Clinical Value for Diagnosis and Prognosis of Signal Sequence Receptor 1 (SSR1) and Its Potential Mechanism in Hepatocellular Carcinoma: A Comprehensive Study Based on High-Throughput Data Analysis. PMID: 34744454
A tetratricopeptide repeat domain-containing protein SSR1 located in mitochondria is involved in root development and auxin polar transport in Arabidopsis. PMID: 26072661
CA-SSR1 Polymorphism in Intron 1 of the EGFR Gene in Patients with Malignant Tumors Who Develop Acneiform Rash Associated with the Use of Cetuximab. PMID: 25721848
Healthy cells functionally present TAP-independent SSR1 peptides: implications for selection of clinically relevant antigens. PMID: 33554062
PBX2-Mediated circTLK1 Activates JAK/STAT Signaling to Promote Gliomagenesis via miR-452-5p/SSR1 Axis. PMID: 34721518
The Role of TRAPγ/SSR3 in Preproinsulin Translocation Into the Endoplasmic Reticulum. PMID: 34857543
The status of EGFR CA SSR1 is a potential prognostic factor for patients with oral squamous cell carcinoma. PMID: 21530363
Correlations between EGFR gene polymorphisms and pleural metastasis of lung adenocarcinoma. PMID: 27601918
Comprehensive bioinformatics analysis reveals the hub genes and pathways associated with multiple myeloma. PMID: 35192775
A Novel Small RNA Regulates Tolerance and Virulence in Shigella flexneri by Responding to Acidic Environmental Changes. PMID: 27014636
Anchorage of Candida albicans Ssr1 to the cell wall, and transcript profiling of the null mutant. PMID: 16024227
Biosynthesis and statistical optimization of polyhydroxyalkanoate (PHA) produced by Bacillus cereus VIT-SSR1 and fabrication of biopolymer films for sustained drug release. PMID: 31128180
Mutation in the Trapalpha/Ssr1 gene, encoding translocon-associated protein alpha, results in outflow tract morphogenetic defects. PMID: 17015483
Deficient endoplasmic reticulum translocon-associated protein complex limits the biosynthesis of proinsulin and insulin. PMID: 33811688
Epidermal growth factor receptor intron 1 polymorphism and microsatellite instability in sporadic colorectal cancer. PMID: 33552252
The Effects of the Transforming Growth Factor-β1 (TGF-β1) Signaling Pathway on Cell Proliferation and Cell Migration are Mediated by Ubiquitin Specific Protease 4 (USP4) in Hypertrophic Scar Tissue and Primary Fibroblast Cultures. PMID: 32308208
Highly mutable tandem DNA repeats generate a cell wall protein variant more frequent in disease-causing Candida albicans isolates than in commensal isolates. PMID: 28662107
Polymorphisms, mutations, and amplification of the EGFR gene in non-small cell lung cancers. PMID: 17455987
Differential expression of somatostatin receptors, P44/42 MAPK, and mTOR activation in medulloblastomas and primitive neuroectodermal tumors. PMID: 23455179
Molecular Cloning, Carbohydrate Specificity and the Crystal Structure of Two Sclerotium rolfsii Lectin Variants. PMID: 26076107
Combined assessment of EGFR-related molecules to predict outcome of 1st-line cetuximab-containing chemotherapy for metastatic colorectal cancer. PMID: 27104867
Germination variation in Arabidopsis thaliana accessions under moderate osmotic and salt stresses. PMID: 20861274
Assessment of autonomic dysfunction in patients with type 2 diabetes using reactive hyperemia. PMID: 23583956
Expanding the phenotype associated with interstitial 6p25.1p24.3 microdeletion: a new case and review of the literature. PMID: 33707360
Comparative analysis of Mycobacterium avium subsp. paratuberculosis isolates from cattle, sheep and goats by short sequence repeat and pulsed-field gel electrophoresis typing. PMID: 19032737
In Ovo and In Silico Evaluation of the Anti-Angiogenic Potential of Syringin. PMID: 33268982
Effect of heat pre-conditioning on recovery following exercise-induced muscle damage. PMID: 34746835
Identification, characterization, and biological activity of somatostatin receptors in human neuroblastoma cell lines. PMID: 8261433
Lung Carcinoids: Long-Term Surgical Results and the Lack of Prognostic Value of Somatostatin Receptors and Other Novel Immunohistochemical Markers. PMID: 30244255
Local cold effect on the excitability recovery curve of the sympathetic skin response. PMID: 15646007
The impact of epidermal growth factor receptor gene status on gefitinib-treated Japanese patients with non-small-cell lung cancer. PMID: 17192902
Metagenomic Profiling of Soil Microbes to Mine Salt Stress Tolerance Genes. PMID: 29472909
Microsatellite markers for mungbean developed from sequence database. PMID: 21564770
Characterization of sulfur-oxidizing bacteria isolated from mustard (Brassica juncea L.) rhizosphere having the capability of improving sulfur and nitrogen uptake. PMID: 36260818
Gender-specific transcriptional profiling of marine medaka (Oryzias melastigma) liver upon BDE-47 exposure. PMID: 23962555
TGF-B1 pathway as biological marker of bladder carcinoma schistosomal and non-schistosomal. PMID: 21429769
Sudomotor skin responses following nerve and brain stimulation. PMID: 7507432
Dynamic changes of 3'UTR length during oocyte-to-zygote transition of in vitro pig embryos. PMID: 36755113
Mining for SSRs and FDMs from expressed sequence tags of Camellia sinensis. PMID: 22493533
Mutations in the translocon-associated protein complex subunit SSR3 cause a novel congenital disorder of glycosylation. PMID: 30945312
Comparison of molecular profile in triple-negative inflammatory and non-inflammatory breast cancer not of mesenchymal stem-like subtype. PMID: 31532791
Proteomic analysis of a Candida albicans pir32 null strain reveals proteins involved in adhesion, filamentation and virulence. PMID: 29554112
Two patients with intellectual disability, overlapping facial features, and overlapping deletions in 6p25.1p24.3. PMID: 23183317
Pb2+ exposure induced microsatellite instability in Pisum sativum in a locus related with glutamine metabolism. PMID: 23174146
Association of common polymorphisms with gestational diabetes mellitus in Japanese women: A case-control study. PMID: 28202837
EGFR polymorphism as a predictor of clinical outcome in advanced lung cancer patients treated with EGFR-TKI. PMID: 23074112
SSR2(a) receptor expression and adrenergic/cholinergic characteristics in differentiated SH-SY5Y cells. PMID: 12675130
Investigation of the effects of estrogen on skeletal gene expression during zebrafish larval head development. PMID: 27069811
Replication Study in a Japanese Population of Six Susceptibility Loci for Type 2 Diabetes Originally Identified by a Transethnic Meta-Analysis of Genome-Wide Association Studies. PMID: 27115357
Cardenolide Increase in Foxglove after 2,1,3-Benzothiadiazole Treatment Reveals a Potential Link between Cardenolide and Phytosterol Biosynthesis. PMID: 36222367
Acute SSRI administration affects the processing of social cues in healthy volunteers. PMID: 12496951
Three different types of surgeon-specific stress reactions identified by laparoscopic simulation in a virtual scenario. PMID: 17943357
Genetic ablation of ataxin-2 increases several global translation factors in their transcript abundance but decreases translation rate. PMID: 25721894
Hypoxic conditions and iron restriction affect the cell-wall proteome of Candida albicans grown under vagina-simulative conditions. PMID: 18227255
Deciphering the network of cholesterol biosynthesis in Paris polyphylla laid a base for efficient diosgenin production in plant chassis. PMID: 36849090
Cytoprotective role of the fatty acid binding protein 4 against oxidative and endoplasmic reticulum stress in 3T3-L1 adipocytes. PMID: 25161868
Effectiveness of combination of Mini-and Microsatellite loci to sub-type Mycobacterium avium subsp. paratuberculosis Italian type C isolates. PMID: 21929793
Prospective molecular marker analyses of EGFR and KRAS from a randomized, placebo-controlled study of erlotinib maintenance therapy in advanced non-small-cell lung cancer. PMID: 21969500
Factors influencing preferential utilization of RNA polymerase containing sigma-38 in stationary-phase gene expression in Escherichia coli. PMID: 15357303
Degenerative evolution and functional diversification of type-III secretion systems in the insect endosymbiont Sodalis glossinidius. PMID: 15574807
Gene expression networks and functionally enriched pathways involved in the response of domestic chicken to acute heat stress. PMID: 37205120
Induction of mitogynogenetic diploids and identification of WW super-female using sex-specific SSR markers in half-smooth tongue sole (Cynoglossus semilaevis). PMID: 21735350
Massive genome erosion and functional adaptations provide insights into the symbiotic lifestyle of Sodalis glossinidius in the tsetse host. PMID: 16365377
Excitability recovery curve of the sympathetic skin response in healthy volunteers and patients with palmar hyperhidrosis. PMID: 11018490
The type 2 diabetes risk allele of TMEM154-rs6813195 associates with decreased beta cell function in a study of 6,486 Danes. PMID: 25799151
Cross reactivity of three T cell attracting murine chemokines stimulating the CXC chemokine receptor CXCR3 and their induction in cultured cells and during allograft rejection. PMID: 11500837
Nucleotide sequence of the internal transcribed spacers of ribosomal DNA in Picea abies Karst. PMID: 10902913