Single Nucleotide Polymorphisms in XMN1-HBG2, HBS1L-MYB, and BCL11A and Their Relation to High Fetal Hemoglobin Levels That Alleviate Anemia. PMID: 35741184
Mammalian Hbs1L deficiency causes congenital anomalies and developmental delay associated with Pelota depletion and 80S monosome accumulation. PMID: 30707697
HBS1L-MYB intergenic variants modulate fetal hemoglobin via long-range MYB enhancers. PMID: 24614105
Detection of BCL11A and HBS1L-MYB Genotypes in Sickle Cell Anemia. PMID: 33100714
The ASC-1 Complex Disassembles Collided Ribosomes. PMID: 32579943
Epigenetic Insights and Potential Modifiers as Therapeutic Targets in β-Thalassemia. PMID: 34070036
Multi-trait and cross-population genome-wide association studies across autoimmune and allergic diseases identify shared and distinct genetic component. PMID: 35753705
Unique Polymorphisms at BCL11A, HBS1L-MYB and HBB Loci Associated with HbF in Kuwaiti Patients with Sickle Cell Disease. PMID: 34204365
MECOM, HBS1L-MYB, THRB-RARB, JAK2, and TERT polymorphisms defining the genetic predisposition to myeloproliferative neoplasms: A study on 939 patients. PMID: 29047144
Disruption of the Hbs1l-Myb locus causes hereditary persistence of fetal hemoglobin in a mouse model. PMID: 23428869
Fetal hemoglobin-boosting haplotypes of BCL11A gene and HBS1L-MYB intergenic region in the prediction of clinical and hematological outcomes in a cohort of children with sickle cell anemia. PMID: 36167770
The HBS1L-MYB intergenic region on chromosome 6q23.3 influences erythrocyte, platelet, and monocyte counts in humans. PMID: 17712044
Existence of HbF Enhancer Haplotypes at HBS1L-MYB Intergenic Region in Transfusion-Dependent Saudi β-Thalassemia Patients. PMID: 28280727
The HBS1L-MYB intergenic region on chromosome 6q23 is a quantitative trait locus controlling fetal haemoglobin level in carriers of beta-thalassaemia. PMID: 18697826
The HBS1L-MYB intergenic interval associated with elevated HbF levels shows characteristics of a distal regulatory region in erythroid cells. PMID: 19528534
Induction of fetal hemoglobin: Lentiviral shRNA knockdown of HBS1L in β0-thalassemia/HbE erythroid cells. PMID: 36888630
The association of HBG2, BCL11A, and HBS1L-MYB polymorphisms to thalidomide response in Chinese β-thalassemia patients. PMID: 32387854
Functional polymorphisms of BCL11A and HBS1L-MYB genes affect both fetal hemoglobin level and clinical outcomes in a cohort of children with sickle cell anemia. PMID: 32447424
Intergenic variants of HBS1L-MYB are responsible for a major quantitative trait locus on chromosome 6q23 influencing fetal hemoglobin levels in adults. PMID: 17592125
A short splicing isoform of HBS1L links the cytoplasmic exosome and SKI complexes in humans. PMID: 28204585
Genetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predisposes to myeloproliferative neoplasms. PMID: 25849990
A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis. PMID: 33536631
Protective BCL11A and HBS1L-MYB polymorphisms in a cohort of 102 Congolese patients suffering from sickle cell anemia. PMID: 28332727
Influence of BCL11A, HBS1L-MYB, HBBP1 single nucleotide polymorphisms and the HBG2 XmnI polymorphism On Hb F levels. PMID: 23094636
Modulatory effect of single nucleotide polymorphism in Xmn1, BCL11A and HBS1L-MYB loci on foetal haemoglobin levels in β-thalassemia major and Intermedia patients. PMID: 34091621
A long noncoding RNA from the HBS1L-MYB intergenic region on chr6q23 regulates human fetal hemoglobin expression. PMID: 29227829
Polymorphism at BCL11A compared to HBS1L-MYB loci explains less of the variance in HbF in patients with sickle cell disease in Cameroon. PMID: 25488618
Safety and efficacy of thalidomide in patients with transfusion-dependent β-thalassemia: a randomized clinical trial. PMID: 34795208
Germline variations at JAK2, TERT, HBS1L-MYB and MECOM and the risk of myeloproliferative neoplasms in Taiwanese population. PMID: 29100304
Genotyping of BCL11A and HBS1L-MYB SNPs associated with fetal haemoglobin levels: a SNaPshot minisequencing approach. PMID: 24502199
DNA polymorphisms at BCL11A, HBS1L-MYB and Xmn1-HBG2 site loci associated with fetal hemoglobin levels in sickle cell anemia patients from Northern Brazil. PMID: 25084696
Association of SNP in exon 1 of HBS1L with hemoglobin F level in beta0-thalassemia/hemoglobin E. PMID: 18839276
Genetic Variants at BCL11A and HBS1L-MYB loci Influence Hb F Levels in Chinese Zhuang β-Thalassemia Intermedia Patients. PMID: 28361591
A 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expression. PMID: 21385855
Influence of single nucleotide polymorphisms in the BCL11A and HBS1L-MYB gene on the HbF levels and clinical severity of sickle cell anaemia patients. PMID: 27098811
Modifying effect of XmnI, BCL11A, and HBS1L-MYB on clinical appearances: A study on β-thalassemia and hemoglobin E/β-thalassemia patients in Indonesia. PMID: 27009595
The Impact of XmnI-HBG2, BCL11A and HBS1L-MYB Single Nucleotide Polymorphisms on Hb F Variation of Hematologically Normal Iranian Individuals. PMID: 27117569
Association of variants at BCL11A and HBS1L-MYB with hemoglobin F and hospitalization rates among sickle cell patients in Cameroon. PMID: 24667352
Meta-analysis of 2040 sickle cell anemia patients: BCL11A and HBS1L-MYB are the major modifiers of HbF in African Americans. PMID: 22936743
DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease. PMID: 18667698
The XmnI (G)gamma polymorphism influences hemoglobin F synthesis contrary to BCL11A and HBS1L-MYB SNPs in a cohort of 57 beta-thalassemia intermedia patients. PMID: 20472475
Fetal haemoglobin induction in sickle cell disease. PMID: 29143315
Ribosome pausing, arrest and rescue in bacteria and eukaryotes. PMID: 28138069
Predictive SNPs for β0-thalassemia/HbE disease severity. PMID: 33990643
Genetic Modifiers of Fetal Haemoglobin in Sickle Cell Disease. PMID: 30478714
Functional mapping of microRNA promoters with dCas9 fused to transcriptional regulators. PMID: 37214422
Epigenomic analysis of KLF1 haploinsufficiency in primary human erythroblasts. PMID: 35013432
Fetal hemoglobin regulating genetic variants identified in homozygous (HbSS) and heterozygous (HbSA) subjects from South Mexico. PMID: 36130307
Recent advances in globin research using genome-wide association studies and gene editing. PMID: 26866328
Sickle cell disease and H3Africa: enhancing genomic research on cardiovascular diseases in African patients. PMID: 25962948
A systematic review of known mechanisms of hydroxyurea-induced fetal hemoglobin for treatment of sickle cell disease. PMID: 26327494
Discovering the genetics underlying foetal haemoglobin production in adults. PMID: 19344402
Variability of hemoglobin F expression in hemoglobin EE disease: hematological and molecular analysis. PMID: 24581976
The role of eosinophils and basophils in allergic diseases considering genetic findings. PMID: 23974679
Fetal hemoglobin modulates neurocognitive performance in sickle cell anemia✰,✰✰. PMID: 35303690
Extraction of mRNA from Stalled Ribosomes by the Ski Complex. PMID: 32006463
Control of fetal hemoglobin: new insights emerging from genomics and clinical implications. PMID: 19808799
Three fingers on the switch: Krüppel-like factor 1 regulation of γ-globin to β-globin gene switching. PMID: 23474875
Genetic regulation of fetal hemoglobin across global populations. PMID: 36993312
An Expert Review of Pharmacogenomics of Sickle Cell Disease Therapeutics: Not Yet Ready for Global Precision Medicine. PMID: 27636225
cMYB is involved in the regulation of fetal hemoglobin production in adults. PMID: 16861354
Genotypic Diversity among Angolan Children with Sickle Cell Anemia. PMID: 34069401
Significance of genetic modifiers of hemoglobinopathies leading towards precision medicine. PMID: 34686692
Defects in translation-dependent quality control pathways lead to convergent molecular and neurodevelopmental pathology. PMID: 33899734
Structure of a Cytoplasmic 11-Subunit RNA Exosome Complex. PMID: 27345150
Influences of genetic variation on fetal hemoglobin. PMID: 22023465
[Predictors of Hematologic Responses in Patients with Non-Transfusion-Dependent β-Thalassemia Receiving Thalidomide Therapy]. PMID: 36208259
ATF4 Regulates MYB to Increase γ-Globin in Response to Loss of β-Globin. PMID: 32755585
Association of HMIP1 C-893A polymorphism and disease severity in patients with sickle cell anemia. PMID: 32665180
mRNA levels can be reduced by antisense oligonucleotides via no-go decay pathway. PMID: 31165876
[Progress on genes related to fetal hemoglobin quantitative trait]. PMID: 20423883
Molecular Analysis of Non-Transfusion Dependent Thalassemia Associated with Hemoglobin E-β-Thalassemia Disease without α-Thalassemia. PMID: 31308914
A survey of genetic fetal-haemoglobin modifiers in Nigerian patients with sickle cell anaemia. PMID: 29879141
HbF-promoting polymorphisms may specifically reduce the residual risk of cerebral vasculopathy in SCA children with alpha-thalassemia. PMID: 33216016
A genetic score for the prediction of beta-thalassemia severity. PMID: 25480500
Dynamic Regulation of a Ribosome Rescue Pathway in Erythroid Cells and Platelets. PMID: 27681415
Association Between Genetic Polymorphisms and Hb F Levels in Heterozygous β-Thalassemia 3.5 kb Deletions. PMID: 32878504
Identification of novel O-GlcNAc transferase substrates using yeast cells expressing OGT. PMID: 33229814
Amelioration of Sardinian beta0 thalassemia by genetic modifiers. PMID: 19696200
Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci. PMID: 28218758
HbA2 levels in normal adults are influenced by two distinct genetic mechanisms. PMID: 23043469
Cellular response to small molecules that selectively stall protein synthesis by the ribosome. PMID: 30875366
Identification of WTAP-related genes by weighted gene co-expression network analysis in ovarian cancer. PMID: 32998774
Genetic regulation of fetal haemoglobin in inherited bone marrow failure syndromes. PMID: 23713742
Variation at 3p24.1 and 6q23.3 influences the risk of Hodgkin's lymphoma. PMID: 24149102
The genetics of hemoglobin A2 regulation in sickle cell anemia. PMID: 25042611
Molecular Understanding of Non-Transfusion-Dependent Thalassemia Associated with Hemoglobin E-β-Thalassemia in Northeast Thailand. PMID: 27710960
Dynamic long-range chromatin interactions control Myb proto-oncogene transcription during erythroid development. PMID: 22157820
Genetic Modifiers of Fetal Haemoglobin (HbF) and Phenotypic Severity in β-Thalassemia Patients. PMID: 30289070
Comprehensive analysis of mitochondrial and nuclear DNA variations in patients affected by hemoglobinopathies: A pilot study. PMID: 33091040
Genetics of fetal hemoglobin in Tanzanian and British patients with sickle cell anemia. PMID: 21068433
2SNP heritability and effects of genetic variants for neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio. PMID: 29066854
Hyperhaemolysis in a pregnant woman with a homozygous β0 -thalassemia mutation and two genetic modifiers. PMID: 33960744
Multimetric feature selection for analyzing multicategory outcomes of colorectal cancer: random forest and multinomial logistic regression models. PMID: 34537824
The Hbs1-Dom34 protein complex functions in non-stop mRNA decay in mammalian cells. PMID: 23667253
Associations between single nucleotide polymorphisms and erythrocyte parameters in humans: A systematic literature review. PMID: 31097152
The RNA surveillance complex Pelo-Hbs1 is required for transposon silencing in the Drosophila germline. PMID: 26124316
Quantitative Trait Loci Influencing Hb F Levels in Southern Thai Hb E (HBB: c.79G>A) Heterozygotes. PMID: 29457528
Analysis of the rs35959442 polymorphism in Hb E/β-thalassemia in Guangxi Province of the Republic of China. PMID: 22191716
Fine-mapping at three loci known to affect fetal hemoglobin levels explains additional genetic variation. PMID: 21057501
Genetics of fetal hemoglobin in tribal Indian patients with sickle cell anemia. PMID: 25651163
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