Catalog No.
PHC98501
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CD56/NCAM1 (Glu30-Glu352).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
NCAM-1, NCAM1, CD56, N-CAM-1, NCAM, Neural cell adhesion molecule 1
Purification
Purified by antigen affinity column.
Accession
P13591
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
CD56 regulates human NK cell cytotoxicity through Pyk2. PMID: 32510326
CD56bright natural killer (NK) cells: an important NK cell subset. PMID: 19278419
Role of CD56 in Normal Kidney Development and Wilms Tumorigenesis. PMID: 27935326
Identification of a peptide targeting CD56. PMID: 32747027
CD56 lymphomas. PMID: 8554118
CD56+ angioimmunoblastic T-cell lymphoma with evans syndrome : a case report and review of the literature. PMID: 23801132
The Broad Spectrum of Human Natural Killer Cell Diversity. PMID: 29166586
Human NK cells responses are enhanced by CD56 engagement. PMID: 35775327
Prognostic significance of CD56 expression in patients with multiple myeloma: a meta-analysis. PMID: 35068378
CD56. PMID: 11215829
To be or not to be: the role of CD56 in multiple myeloma. PMID: 36702332
Pediatric CD56+ anaplastic large cell lymphoma: a review of the literature. PMID: 17149964
Single-cell RNA sequencing deconvolutes the in vivo heterogeneity of human bone marrow-derived mesenchymal stem cells. PMID: 34803492
Primary CD56 positive lymphomas of the gastrointestinal tract. PMID: 11169934
Pediatric CD8⁺CD56⁺ non-poikilodermatous mycosis fungoides: case report and review of the literature. PMID: 24698938
CD56 expression in benign and malignant thyroid lesions. PMID: 30173227
CD56 and RUNX1 isoforms in AML prognosis and their therapeutic potential. PMID: 26706848
Multiomic analysis reveals cell-type-specific molecular determinants of COVID-19 severity. PMID: 35690068
CD4+/CD56+ hematodermic neoplasm: presentation of 2 cases and review of the concept of an uncommon tumor originated in plasmacytoid dendritic cells expressing CD123 (IL-3 receptor alpha). PMID: 18091395
Can we define CD3+CD56+ cells as NKT cells with impunity? PMID: 33662591
CD56+ B-cell Neurolymphomatosis in a Cat. PMID: 31159947
Aberrant myelomonocytic CD56 expression in Down syndrome is frequent and not associated with leukemogenesis. PMID: 33890142
CD56-positive large B-cell lymphoma. PMID: 17122631
CD56+ T cells inhibit HIV-1 infection of macrophages. PMID: 22591692
Uterine CD56+ cell density and euploid miscarriage in women with a history of recurrent miscarriage: A clinical descriptive study. PMID: 32976648
Activated T cells and cytokine-induced CD3+CD56+ killer cells. PMID: 9063373
[Granulated CD56 lymphocytes of decidual tissue]. PMID: 8746101
Prognostic Significance of CD56 Antigen Expression in Patients with De Novo Non-M3 Acute Myeloid Leukemia. PMID: 33928145
[Expression of CD56 in Multiple Myeloma Cells and Its Relationship with Extramedullary Disease and Extramedullary Relapse]. PMID: 33812430
Expression of CD56 in patients with adenomyosis and its correlation with dysmenorrhea. PMID: 26344352
Single-cell profiling reveals periventricular CD56bright NK cell accumulation in multiple sclerosis. PMID: 35536009
High expression of CD56 may be associated with favorable overall survival in intermediate-risk acute myeloid leukemia. PMID: 33594945
Significance of cell adhesion molecules, CD56/NCAM in particular, in human tumor growth and spreading. PMID: 11820619
Prognostic significance of surface markers expressed in multiple myeloma: CD56 and other antigens. PMID: 15061198
Changes of CD3+CD56+ γδ T cell number and apoptosis during hospital admission are related to mortality in septic patients. PMID: 35176483
CD56 antibody: old-fashioned or still trendy in endocrine lung tumors. PMID: 25140506
CD56-negative NK cells with impaired effector function expand in CMV and EBV co-infected healthy donors with age. PMID: 30686790
Human Hepatic CD56bright NK Cells Display a Tissue-Resident Transcriptional Profile and Enhanced Ability to Kill Allogenic CD8+ T Cells. PMID: 35865550
Deciphering the Significance of CD56 Expression in Pediatric Acute Myeloid Leukemia: A Report from the Children's Oncology Group. PMID: 31294507
Is absence of CD56 a predictive factor for peripheral blood stem cell mobilization failure in patients with multiple myeloma? PMID: 33333593
Clinical Significance of CD200 and CD56 Expression in Patients with Acute Myeloid Leukemia. PMID: 32212802
NCAM1 (CD56) promotes leukemogenesis and confers drug resistance in AML. PMID: 30814062
Autoantibodies against NCAM1 from patients with schizophrenia cause schizophrenia-related behavior and changes in synapses in mice. PMID: 35492247
NCAM1 and GDF15 are biomarkers of Charcot-Marie-Tooth disease in patients and mice. PMID: 35148379
NCAM1 Polysialylation: The Prion Protein's Elusive Reason for Being? PMID: 27879349
NCAM1 is the Target of miRNA-572: Validation in the Human Oligodendroglial Cell Line. PMID: 28332001
Retraction Note: Downregulation of microRNA-324-3p inhibits lung cancer by blocking the NCAM1-MAPK axis through ALX4. PMID: 34112920
DNMT3B regulates proliferation of A549 cells through the microRNA-152-3p/NCAM1 pathway. PMID: 34820010
Human neural cell type-specific extracellular vesicle proteome defines disease-related molecules associated with activated astrocytes in Alzheimer's disease brain. PMID: 35029059
Schwann cells induce cancer cell dispersion and invasion. PMID: 26999607
NCAM1 supports therapy resistance and LSC function in AML. PMID: 31122937
The engineered peptide construct NCAM1-Aβ inhibits fibrillization of the human prion protein (PrP). PMID: 35143147
Retraction: Long non-coding RNA KCNQ1OT1 regulates cell proliferation, apoptosis and chemo-sensitivity through modulating the miR-186-5p/NCAM1 axis in acute myeloid leukemia cells. PMID: 35427011
NCAM1-TTC12-ANKK1-DRD2 variants and smoking motives as intermediate phenotypes for nicotine dependence. PMID: 25273375
NCAM1/FGF module serves as a putative pleuropulmonary blastoma therapeutic target. PMID: 31477684
The association between NCAM1 levels and behavioral phenotypes in children with autism spectrum disorder. PMID: 30423390
A functional SNP rs895819 on pre-miR-27a is associated with bipolar disorder by targeting NCAM1. PMID: 35379867
NCAM1 and neurocognition in schizophrenia. PMID: 17161382
Role of the Gut-Brain Axis in the Shared Genetic Etiology Between Gastrointestinal Tract Diseases and Psychiatric Disorders: A Genome-Wide Pleiotropic Analysis. PMID: 36753304
Pro-Inflammatory S100A9 Protein Aggregation Promoted by NCAM1 Peptide Constructs. PMID: 31194501
EXT1 and NCAM1-associated membranous lupus nephritis in a cohort of patients undergoing repeat kidney biopsies. PMID: 35278072
Upregulation of Neural Cell Adhesion Molecule 1 (NCAM1) by hsa-miR-141-3p Suppresses Ameloblastoma Cell Migration. PMID: 32269209
NCAM1 association study of bipolar disorder and schizophrenia: polymorphisms and alternatively spliced isoforms lead to similarities and differences. PMID: 17413444
siRNA-mediated NCAM1 gene silencing suppresses oxidative stress in pre-eclampsia by inhibiting the p38MAPK signaling pathway. PMID: 31353686
The NCAM1 gene set is linked to depressive symptoms and their brain structural correlates in healthy individuals. PMID: 28334615
NCAM1-TTC12-ANKK1-DRD2 gene cluster and the clinical and genetic heterogeneity of adults with ADHD. PMID: 25989041
Identification of Circular RNA-Based Immunomodulatory Networks in Colorectal Cancer. PMID: 35155186
TGF-β1 affects cell-cell adhesion in the heart in an NCAM1-dependent mechanism. PMID: 28870505
Chemical proteomics tracks virus entry and uncovers NCAM1 as Zika virus receptor. PMID: 32753727
Downregulation of microRNA-324-3p inhibits lung cancer by blocking the NCAM1-MAPK axis through ALX4. PMID: 33087824
Rapid Turnover of Cortical NCAM1 Regulates Synaptic Reorganization after Peripheral Nerve Injury. PMID: 29346771
A ZIP6-ZIP10 heteromer controls NCAM1 phosphorylation and integration into focal adhesion complexes during epithelial-to-mesenchymal transition. PMID: 28098160
Upregulation of KLK8 contributes to CUMS-induced hippocampal neuronal apoptosis by cleaving NCAM1. PMID: 37076499
Detection of natural antisense non-coding RNAs transcribed from Ncam1 in mice tissues at several developmental stages. PMID: 26405542
Spatial Organization and Prognostic Significance of NK and NKT-like Cells via Multimarker Analysis of the Colorectal Cancer Microenvironment. PMID: 34937729
NCAM1, TACR1 and NOS genes and temperament: a study on suicide attempters and controls. PMID: 21577011
Reactivation of NCAM1 defines a subpopulation of human adult kidney epithelial cells with clonogenic and stem/progenitor properties. PMID: 24055371
Lack of association between NCAM1 and early onset schizophrenia in a family based study in Shandong peninsula of China. PMID: 27625800
ELF1 suppresses autophagy to reduce cisplatin resistance via the miR-152-3p/NCAM1/ERK axis in lung cancer cells. PMID: 36846943
Effects of pharmacological treatments on hippocampal NCAM1 and ERK2 expression in epileptic rats with cognitive dysfunction. PMID: 27588125
For research use only. Not for human or drug use.
