Catalog No.
PHF03801
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human USP14 (Met1-Gln494).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Deubiquitinating enzyme 14, TGT, Ubiquitin thioesterase 14, Ubiquitin carboxyl-terminal hydrolase 14, Ubiquitin-specific-processing protease 14, USP14
Purification
Purified by antigen affinity column.
Accession
P54578
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
USP14 inhibition promotes recovery by protecting BBB integrity and attenuating neuroinflammation in MCAO mice., PMID:37269080
Inhibition of USP14 suppresses the formation of foam cell by promoting CD36 degradation., PMID:31970862
The deubiquitinating enzyme Usp14 controls ciliogenesis and Hedgehog signaling., PMID:30388222
Repurposing an antidandruff agent to treating cancer: zinc pyrithione inhibits tumor growth via targeting proteasome-associated deubiquitinases., PMID:28086217
Expression of possible targets for new proteasome inhibitors in diffuse large B-cell lymphoma., PMID:27301795
Usp14 deficiency increases tau phosphorylation without altering tau degradation or causing tau-dependent deficits., PMID:23144711
WITHDRAWN: USP14 stabilizes calcineurin and regulates NFAT/AP-1 dependent IL-4 transcription as a novel calcineurin-binding protein., PMID:19896943
For research use only. Not for human or drug use.
