Anti-Human LAMA3 Polyclonal Antibody

Catalog No.

PHH37101

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human LAMA3 (Leu47-Gly296).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:200, WB: 1:1000-1:4000

Target

Laminin-7 subunit alpha, Laminin-5 subunit alpha, Kalinin subunit alpha, E170, Epiligrin subunit alpha, Nicein subunit alpha, Laminin subunit alpha-3, LAMA3, Epiligrin 170 kDa subunit, Laminin-6 subunit alpha, LAMNA

Concentration

1.31 mg/ml

Purification

Purified by antigen affinity column.

Accession

Q16787

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Molecular and Clinical Outcomes After Intravenous Gentamicin Treatment for Patients With Junctional Epidermolysis Bullosa Caused by Nonsense Variants., PMID:35234826

Dedicator of Cytokinesis 5 Regulates Keratinocyte Function and Promotes Diabetic Wound Healing., PMID:33627322

Surfce Functionalized via AdLAMA3 Multilayer Coating for Re-epithelization Around Titanium Implants., PMID:32596232

Expression of adhesion and extracellular matrix genes in human blastocysts upon attachment in a 2D co-culture system., PMID:29846687

Substrate-mediated gene transduction of LAMA3 for promoting biological sealing between titanium surface and gingival epithelium., PMID:29096376

Spatiotemporally Controlled Ablation of Klf5 Results in Dysregulated Epithelial Homeostasis in Adult Mouse Corneas., PMID:28910443

Lack of K140 immunoreactivity in junctional epidermolysis bullosa skin and keratinocytes associates with misfolded laminin epidermal growth factor-like motif 2 of the β3 short arm., PMID:28561256

RNA-seq analysis of impact of PNN on gene expression and alternative splicing in corneal epithelial cells., PMID:26900324

Using immunofluorescence (antigen) mapping in the diagnosis and classification of epidermolysis bullosa: a first report from Iran., PMID:26220012

Dermal eosinophilic infiltrate in junctional epidermolysis bullosa., PMID:25950805

Extracellular matrix of adipogenically differentiated mesenchymal stem cells reveals a network of collagen filaments, mostly interwoven by hexagonal structural units., PMID:23851162

Herlitz junctional epidermolysis bullosa: diagnostic features, mutational profile, incidence and population carrier frequency in the Netherlands., PMID:21801158

Efficiency of translation termination in humans is highly dependent upon nucleotides in the neighbourhood of a (premature) termination codon., PMID:21693480

Identification of a novel family of laminin N-terminal alternate splice isoforms: structural and functional characterization., PMID:19773554

Granulation tissue in the eyelid margin and conjunctiva in junctional epidermolysis bullosa with features of laryngo-onycho-cutaneous syndrome., PMID:17362460

Increase of laminin 5 synthesis in human keratinocytes by acute wound fluid, inflammatory cytokines and growth factors, and lysophospholipids., PMID:15541073

Novel and recurrent mutations in the laminin-5 genes causing lethal junctional epidermolysis bullosa: molecular basis and clinical course of Herlitz disease., PMID:15538630

Targeted inactivation of murine laminin gamma2-chain gene recapitulates human junctional epidermolysis bullosa., PMID:14632187

Moderation of phenotypic severity in dystrophic and junctional forms of epidermolysis bullosa through in-frame skipping of exons containing non-sense or frameshift mutations., PMID:10469327

Targeted disruption of the LAMA3 gene in mice reveals abnormalities in survival and late stage differentiation of epithelial cells., PMID:10366601

Corrective transduction of human epidermal stem cells in laminin-5-dependent junctional epidermolysis bullosa., PMID:9650620

Morphological classification of nuchal skin in human fetuses with trisomy 21, 18, and 13 at 12-18 weeks and in a trisomy 16 mouse., PMID:9497154

Predominance of the recurrent mutation R635X in the LAMB3 gene in European patients with Herlitz junctional epidermolysis bullosa has implications for mutation detection strategy., PMID:9242513

Immunohistochemical analysis of the skin in junctional epidermolysis bullosa using laminin 5 chain specific antibodies is of limited value in predicting the underlying gene mutation., PMID:9217810

The laminin alpha chains: expression, developmental transitions, and chromosomal locations of alpha1-5, identification of heterotrimeric laminins 8-11, and cloning of a novel alpha3 isoform., PMID:9151674

Compound heterozygosity for a dominant glycine substitution and a recessive internal duplication mutation in the type XVII collagen gene results in junctional epidermolysis bullosa and abnormal dentition., PMID:8669466

Cloning of the laminin alpha 3 chain gene (LAMA3) and identification of a homozygous deletion in a patient with Herlitz junctional epidermolysis bullosa., PMID:8586427

A homozygous nonsense mutation in the alpha 3 chain gene of laminin 5 (LAMA3) in lethal (Herlitz) junctional epidermolysis bullosa., PMID:7633458

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