Catalog No.
PHA01501
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CLCA1 (Asn416-Arg670).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Calcium-activated chloride channel regulator 1, hCLCA1, Calcium-activated chloride channel protein 1, CACC1, CaCC-1, Calcium-activated chloride channel family member 1, hCaCC-1, CLCA1
Purification
Purified by antigen affinity column.
Accession
A8K7I4
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Lignosus rhinocerotis Cooke Ryvarden ameliorates airway inflammation, mucus hypersecretion and airway hyperresponsiveness in a murine model of asthma., PMID:33784348
Analysis of Lung Gene Expression Reveals a Role for Cl- Channels in Diisocyanate-induced Airway Eosinophilia in a Mouse Model of Asthma Pathology., PMID:32101465
Calcium-activated chloride channel regulator 1 (CLCA1) forms non-covalent oligomers in colonic mucus and has mucin 2-processing properties., PMID:31570526
Safety and immunogenicity of a DNA vaccine encoding human calcium-activated chloride channel 1 (hCLCA1) in asthmatic mice., PMID:23548383
Increased human Ca²⁺-activated Cl⁻ channel 1 expression and mucus overproduction in airway epithelia of smokers and chronic obstructive pulmonary disease patients., PMID:22731784
Interleukin-13 induces mucin 5AC production involving STAT6/SPDEF in human airway epithelial cells., PMID:21275604
Inward-rectifier chloride currents in Reissner's membrane epithelial cells., PMID:20226170
Relationship between calcium-activated chloride channel 1 and MUC5AC in goblet cell hyperplasia induced by interleukin-13 in human bronchial epithelial cells., PMID:16465045
Differential regulation of MUC5AC/Muc5ac and hCLCA-1/mGob-5 expression in airway epithelium., PMID:16151054
Chloride channel gene expression in the rabbit cornea., PMID:15635293
Relationship between a HCO3- -permeable conductance and a CLCA protein from rat pancreatic zymogen granules., PMID:12504118
Characterization of a calcium-activated chloride channel as a shared target of Th2 cytokine pathways and its potential involvement in asthma., PMID:11694454
Cloning a chloride conductance mediator from the apical membrane of porcine ileal enterocytes., PMID:11015605
For research use only. Not for human or drug use.
