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Anti-Human CLCA1 Polyclonal Antibody

Catalog #:   PHA01501 Specific References (13) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: A8K7I4
Overview

Catalog No.

PHA01501

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CLCA1 (Asn416-Arg670).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Calcium-activated chloride channel regulator 1, hCLCA1, Calcium-activated chloride channel protein 1, CACC1, CaCC-1, Calcium-activated chloride channel family member 1, hCaCC-1, CLCA1

Purification

Purified by antigen affinity column.

Accession

A8K7I4

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with CLCA1 antibody (PHA01501) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 29 kDa
    Observed MW: 29 kDa
References

Lignosus rhinocerotis Cooke Ryvarden ameliorates airway inflammation, mucus hypersecretion and airway hyperresponsiveness in a murine model of asthma., PMID:33784348

Analysis of Lung Gene Expression Reveals a Role for Cl- Channels in Diisocyanate-induced Airway Eosinophilia in a Mouse Model of Asthma Pathology., PMID:32101465

Calcium-activated chloride channel regulator 1 (CLCA1) forms non-covalent oligomers in colonic mucus and has mucin 2-processing properties., PMID:31570526

Safety and immunogenicity of a DNA vaccine encoding human calcium-activated chloride channel 1 (hCLCA1) in asthmatic mice., PMID:23548383

Increased human Ca²⁺-activated Cl⁻ channel 1 expression and mucus overproduction in airway epithelia of smokers and chronic obstructive pulmonary disease patients., PMID:22731784

Interleukin-13 induces mucin 5AC production involving STAT6/SPDEF in human airway epithelial cells., PMID:21275604

Inward-rectifier chloride currents in Reissner's membrane epithelial cells., PMID:20226170

Relationship between calcium-activated chloride channel 1 and MUC5AC in goblet cell hyperplasia induced by interleukin-13 in human bronchial epithelial cells., PMID:16465045

Differential regulation of MUC5AC/Muc5ac and hCLCA-1/mGob-5 expression in airway epithelium., PMID:16151054

Chloride channel gene expression in the rabbit cornea., PMID:15635293

Relationship between a HCO3- -permeable conductance and a CLCA protein from rat pancreatic zymogen granules., PMID:12504118

Characterization of a calcium-activated chloride channel as a shared target of Th2 cytokine pathways and its potential involvement in asthma., PMID:11694454

Cloning a chloride conductance mediator from the apical membrane of porcine ileal enterocytes., PMID:11015605

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-Human CLCA1 Polyclonal Antibody [PHA01501]
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